Flemming Steen Jørgensen

Sitert av

	Alle	Siden 2020
Sitater	4166	988
h-indeks	35	17
i10-indeks	82	33

240

120

180

198619871988198919901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202516 7 10 18 33 32 36 33 37 38 29 41 42 39 46 52 55 70 86 93 120 135 132 155 164 176 181 168 141 179 190 178 190 179 148 164 194 210 226 45

Offentlig tilgang

Vis alle

19 artikler

3 artikler

tilgjengelige

ikke tilgjengelige

Basert på finansieringsmandater

Medforfattere

Lars OlsenDepartment of Drug Design and Pharmacology, University of CopenhagenVerifisert e-postadresse på novozymes.com
Carsten Uhd NielsenDepartment of Physics, Chemistry and Pharmacy, Faculty of Sciences, University of Southern DenmarkVerifisert e-postadresse på sdu.dk
Vasanthanathan PoongavanamDocent, Science for Life Laboratory, Uppsala UniversityVerifisert e-postadresse på scilifelab.uu.se
Søren BrunakProfessor of Disease Systems Biology, University of CopenhagenVerifisert e-postadresse på cpr.ku.dk
Birger BrodinProfessor, CNS drug delivery, University of CopenhagenVerifisert e-postadresse på sund.ku.dk
Marco van de WeertAssociate Professor in Biologics formulation, University of CopenhagenVerifisert e-postadresse på sund.ku.dk
Lars HemmingsenDepartment of Chemistry, University of CopenhagenVerifisert e-postadresse på chem.ku.dk
Michael GajhedeProfessor i proteinkrystallografi, Københavns UniversitetVerifisert e-postadresse på sund.ku.dk
R. Stan BrownProfessor of Chemistry, Queen's UniversityVerifisert e-postadresse på chem.queensu.ca
Jukka Rantanen, professor PhDUniversity of CopenhagenVerifisert e-postadresse på sund.ku.dk
Tudor OpreaCEO, Expert Systems IncVerifisert e-postadresse på expertsystems.inc
Qiyuan LiSchool of Medicine, Xiamen UniversityVerifisert e-postadresse på xmu.edu.cn
Anders Skov KristensenUniversity of CopenhagenVerifisert e-postadresse på sund.ku.dk
Kasper B. HansenProfessor, University of MontanaVerifisert e-postadresse på mso.umt.edu
Henrik LeffersSenior Scientist, University of Copenhagen, Denmark. henrik@leffers.proVerifisert e-postadresse på leffers.pro
Patrik RydbergAssociate Director, Computational Chemmistry, Optibrium Ltd.Verifisert e-postadresse på optibrium.com
Hans Bräuner-OsborneProfessor of Molecular Pharmacology, University of CopenhagenVerifisert e-postadresse på sund.ku.dk
Vignir IsbergSenior Manager, NovonesisVerifisert e-postadresse på vignir.org
David N. CooperProfessor of Human Molecular Genetics, Cardiff University, UKVerifisert e-postadresse på cardiff.ac.uk
Peter BrossResearch Unit for Molecular Medicine, Aarhus University HospitalVerifisert e-postadresse på clin.au.dk

Følg

Flemming Steen Jørgensen

Professor, Department of Drug Design and Pharmacology, University of Copenhagen

Verifisert e-postadresse på sund.ku.dk

Molecular modelling computational chemistry structure-activity relationship


Tittel Sorter etter sitater Sorter etter år Sorter etter tittel	Sitert av Sitert av	År
Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities M Groenning, L Olsen, M van de Weert, JM Flink, S Frokjaer, ... Journal of structural biology 158 (3), 358-369, 2007	320	2007
GABAA receptor agonists, partial agonists, and antagonists. Design and therapeutic prospects P Krogsgaard-Larsen, B Frølund, FS Joergensen, A Schousboe Journal of medicinal chemistry 37 (16), 2489-2505, 1994	161	1994
Prediction methods and databases within chemoinformatics: emphasis on drugs and drug candidates SÓ Jónsdóttir, FS Jørgensen, S Brunak Bioinformatics 21 (10), 2145-2160, 2005	143	2005
Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones C Kunick, K Lauenroth, K Wieking, X Xie, C Schultz, R Gussio, ... Journal of Medicinal Chemistry 47 (1), 22-36, 2004	140	2004
A new concept for multidimensional selection of ligand conformations (MultiSelect) and multidimensional scoring (MultiScore) of protein− ligand binding affinities GE Terp, BN Johansen, IT Christensen, FS Jørgensen Journal of medicinal chemistry 44 (14), 2333-2343, 2001	140	2001
Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques P Vasanthanathan, O Taboureau, C Oostenbrink, NPE Vermeulen, ... Drug Metabolism and Disposition 37 (3), 658-664, 2009	122	2009
hERG classification model based on a combination of support vector machine method and GRIND descriptors Q Li, FS Jørgensen, T Oprea, S Brunak, O Taboureau Molecular pharmaceutics 5 (1), 117-127, 2008	116	2008
Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter J Andersen, L Olsen, KB Hansen, O Taboureau, FS Jørgensen, ... Journal of Biological Chemistry 285 (3), 2051-2063, 2010	115	2010
Prediction of cytochrome P450 mediated metabolism L Olsen, C Oostenbrink, FS Jørgensen Advanced drug delivery reviews 86, 61-71, 2015	114	2015
Structural differences of matrix metalloproteinases with potential implications for inhibitor selectivity examined by the GRID/CPCA approach GE Terp, G Cruciani, IT Christensen, FS Jørgensen Journal of medicinal chemistry 45 (13), 2675-2684, 2002	106	2002
Prediction of pH-dependent aqueous solubility of druglike molecules NT Hansen, I Kouskoumvekaki, FS Jørgensen, S Brunak, SO Jonsdottir Journal of chemical information and modeling 46 (6), 2601-2609, 2006	101	2006
Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia AM Buhl, J Jurlander, FS Jørgensen, AM Ottesen, JB Cowland, ... Blood 107 (7), 2904-2911, 2006	100	2006
Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands P Vasanthanathan, J Hritz, O Taboureau, L Olsen, F Steen Jørgensen, ... Journal of chemical information and modeling 49 (1), 43-52, 2009	91	2009
SMARTCyp 3.0: enhanced cytochrome P450 site-of-metabolism prediction server L Olsen, M Montefiori, KP Tran, FS Jørgensen Bioinformatics 35 (17), 3174-3175, 2019	86	2019
Recent advances in GABA agonists, antagonists and uptake inhibitors: structure–activity relationships and therapeutic potential P KROGSGAARD-LARSEN, H HJEDS, E FALCH, FS JØRGENSEN, ... Advances in drug research 17, 381-456, 1988	86	1988
New leads of metallo-β-lactamase inhibitors from structure-based pharmacophore design L Olsen, S Jost, HW Adolph, I Pettersson, L Hemmingsen, FS Jørgensen Bioorganic & medicinal chemistry 14 (8), 2627-2635, 2006	72	2006
Solvent diversity in polymorph screening M Allesø, F Van Den Berg, C Cornett, FS Jørgensen, B Halling-Sørensen, ... Journal of pharmaceutical sciences 97 (6), 2145-2159, 2008	69	2008
Cyclynes. Part 5. Pericyclynes:" exploded cycloalkanes" with unusual orbital interactions and conformational properties. MM2 and STO-3G calculations, x-ray crystal structures … KN Houk, LT Scott, NG Rondan, DC Spellmeyer, G Reinhardt, JL Hyun, ... Journal of the American Chemical Society 107 (23), 6556-6562, 1985	67	1985
Homology modelling of the GABA transporter and analysis of tiagabine binding S Skovstrup, O Taboureau, H Bräuner‐Osborne, FS Jørgensen ChemMedChem 5 (7), 986-1000, 2010	63	2010
Towards an understanding of drug resistance in malaria: three-dimensional structure of Plasmodium falciparum dihydrofolate reductase by homology building T Lemcke, IT Christensen, FS Jørgensen Bioorganic & medicinal chemistry 7 (6), 1003-1011, 1999	62	1999

Systemet kan ikke utføre handlingen. Prøv på nytt senere.

Artikler 1–20

Sitater per år

Duplikatsitater

Sammenslåtte sitater

Legg til medforfattereMedforfattere

Følg

Sitert av

Medforfattere