Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection … HHJ Gerets, K Tilmant, B Gerin, H Chanteux, BO Depelchin, S Dhalluin, ... Cell biology and toxicology 28, 69-87, 2012 | 800 | 2012 |
Intracellular pharmacodynamics of antibiotics S Carryn, H Chanteux, C Seral, MP Mingeot-Leclercq, F Van Bambeke, ... Infectious Disease Clinics 17 (3), 615-634, 2003 | 248 | 2003 |
Comparative stability studies of antipseudomonal β-lactams for potential administration through portable elastomeric pumps (home therapy for cystic fibrosis patients) and motor … E Viaene, H Chanteux, H Servais, MP Mingeot-Leclercq, PM Tulkens Antimicrobial agents and chemotherapy 46 (8), 2327-2332, 2002 | 228 | 2002 |
LPS induces IL-10 production by human alveolar macrophages via MAPKinases-and Sp1-dependent mechanisms H Chanteux, AC Guisset, C Pilette, Y Sibille Respiratory research 8, 1-10, 2007 | 192 | 2007 |
Brivaracetam, a selective high‐affinity synaptic vesicle protein 2A (SV 2A) ligand with preclinical evidence of high brain permeability and fast onset of action JM Nicolas, J Hannestad, D Holden, S Kervyn, N Nabulsi, D Tytgat, ... Epilepsia 57 (2), 201-209, 2016 | 168 | 2016 |
Saccharomyces boulardii upgrades cellular adaptation after proximal enterectomy in rats JP Buts, N De Keyser, S Marandi, D Hermans, EM Sokal, YHE Chae, ... Gut 45 (1), 89-96, 1999 | 111 | 1999 |
Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions JM Nicolas, F Bouzom, C Hugues, AL Ungell Biopharmaceutics & drug disposition 38 (3), 209-230, 2017 | 99 | 2017 |
Cellular pharmacokinetics and pharmacodynamics of the glycopeptide antibiotic oritavancin (LY333328) in a model of J774 mouse macrophages F Van Bambeke, S Carryn, C Seral, H Chanteux, D Tyteca, ... Antimicrobial agents and chemotherapy 48 (8), 2853-2860, 2004 | 95 | 2004 |
Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages C Seral, JM Michot, H Chanteux, MP Mingeot-Leclercq, PM Tulkens, ... Antimicrobial agents and chemotherapy 47 (3), 1047-1051, 2003 | 87 | 2003 |
Stability and compatibility study of cefepime in comparison with ceftazidime for potential administration by continuous infusion under conditions pertinent to ambulatory … N Baririan, H Chanteux, E Viaene, H Servais, PM Tulkens Journal of Antimicrobial Chemotherapy 51 (3), 651-658, 2003 | 76 | 2003 |
Brivaracetam and carbamazepine interaction in healthy subjects and in vitro A Stockis, H Chanteux, M Rosa, P Rolan Epilepsy Research 113, 19-27, 2015 | 57 | 2015 |
A review of the drug− drug interactions of the antiepileptic drug brivaracetam BD Moseley, H Chanteux, JM Nicolas, C Laloyaux, B Gidal, A Stockis Epilepsy research 163, 106327, 2020 | 50 | 2020 |
Effect of rifampin on the disposition of brivaracetam in human subjects: further insights into brivaracetam hydrolysis A Stockis, S Watanabe, AJ Scheen, D Tytgat, B Gerin, M Rosa, ... Drug Metabolism and Disposition 44 (6), 792-799, 2016 | 47 | 2016 |
Effect of gemfibrozil on the metabolism of brivaracetam in vitro and in human subjects JM Nicolas, H Chanteux, M Rosa, S Watanabe, A Stockis Drug Metabolism and Disposition 40 (8), 1466-1472, 2012 | 41 | 2012 |
Potential role for human P‐glycoprotein in the transport of lacosamide C Zhang, H Chanteux, Z Zuo, P Kwan, L Baum Epilepsia 54 (7), 1154-1160, 2013 | 29 | 2013 |
Accumulation and oriented transport of ampicillin in Caco-2 cells from its pivaloyloxymethylester prodrug, pivampicillin H Chanteux, F Van Bambeke, MP Mingeot-Leclercq, PM Tulkens Antimicrobial agents and chemotherapy 49 (4), 1279-1288, 2005 | 28 | 2005 |
Current practices, gap analysis, and proposed workflows for PBPK modeling of cytochrome P450 induction: an industry perspective N Hariparsad, D Ramsden, K Taskar, J Badée, K Venkatakrishnan, ... Clinical Pharmacology & Therapeutics 112 (4), 770-781, 2022 | 25 | 2022 |
Designing out PXR activity on drug discovery projects: a review of structure-based methods, empirical and computational approaches A Hall, H Chanteux, K Ménochet, M Ledecq, MSED Schulze Journal of Medicinal Chemistry 64 (10), 6413-6522, 2021 | 23 | 2021 |
Assessment of cytochrome P450 (1A2, 2B6, 2C9 and 3A4) induction in cryopreserved human hepatocytes cultured in 48-well plates using the cocktail strategy B Gerin, S Dell’Aiera, L Richert, S Smith, H Chanteux Xenobiotica 43 (4), 320-335, 2013 | 23 | 2013 |
Cell Handling, Membrane-Binding Properties and Membrane-Penetration Modeling Approaches of Pivampicillin and Phthalimidomethylampicillin, Two Basic Esters of Ampicillin, in … H Chanteux, I Paternotte, MP Mingeot-Leclercq, R Brasseur, E Sonveaux, ... Pharmaceutical research 20, 624-631, 2003 | 21 | 2003 |