| Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood A Raue, C Kreutz, T Maiwald, J Bachmann, M Schilling, U Klingmüller, ... Bioinformatics 25 (15), 1923-1929, 2009 | 1536 | 2009 |
| Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals U Klingmüller, U Lorenz, LC Cantley, BG Neel, HF Lodish Cell 80 (5), 729-738, 1995 | 1200 | 1995 |
| Comparative proteomic phenotyping of cell lines and primary cells to assess preservation of cell type-specific functions C Pan, C Kumar, S Bohl, U Klingmueller, M Mann Molecular & Cellular Proteomics 8 (3), 443-450, 2009 | 737 | 2009 |
| Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by databased modeling I Swameye, TG Müller, J Timmer, O Sandra, U Klingmüller Proceedings of the National Academy of Sciences 100 (3), 1028-1033, 2003 | 444 | 2003 |
| Lessons learned from quantitative dynamical modeling in systems biology A Raue, M Schilling, J Bachmann, A Matteson, M Schelke, D Kaschek, ... PloS one 8 (9), e74335, 2013 | 409 | 2013 |
| Interaction of the erythropoietin and stem-cell-factor receptors H Wu, U Klingmüller, P Besmer, HF Lodish Nature 377 (6546), 242-246, 1995 | 350 | 1995 |
| The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice M Castoldi, MV Spasic, S Altamura, J Elmén, M Lindow, J Kiss, J Stolte, ... The Journal of clinical investigation 121 (4), 1386-1396, 2011 | 283 | 2011 |
| Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems A Raue, B Steiert, M Schelker, C Kreutz, T Maiwald, H Hass, J Vanlier, ... Bioinformatics 31 (21), 3558-3560, 2015 | 263 | 2015 |
| Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5. U Klingmüller, S Bergelson, JG Hsiao, HF Lodish Proceedings of the National Academy of Sciences 93 (16), 8324-8328, 1996 | 242 | 1996 |
| Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models RJ Weaver, EA Blomme, AE Chadwick, IM Copple, HHJ Gerets, ... Nature Reviews Drug Discovery 19 (2), 131-148, 2020 | 220 | 2020 |
| Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors U Klingmüller, H Wu, JG Hsiao, A Toker, BC Duckworth, LC Cantley, ... Proceedings of the National Academy of Sciences 94 (7), 3016-3021, 1997 | 218 | 1997 |
| Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation H Wu, U Klingmüller, A Acurio, JG Hsiao, HF Lodish Proceedings of the National Academy of Sciences 94 (5), 1806-1810, 1997 | 211 | 1997 |
| Addressing parameter identifiability by model-based experimentation A Raue, C Kreutz, T Maiwald, U Klingmuller, J Timmer IET systems biology 5 (2), 120-130, 2011 | 210 | 2011 |
| Covering a broad dynamic range: information processing at the erythropoietin receptor V Becker, M Schilling, J Bachmann, U Baumann, A Raue, T Maiwald, ... Science 328 (5984), 1404-1408, 2010 | 205 | 2010 |
| Hepadnavirus infection requires interaction between the viral pre-S domain and a specific hepatocellular receptor U Klingmüller, H Schaller Journal of virology 67 (12), 7414-7422, 1993 | 192 | 1993 |
| Simulation methods for optimal experimental design in systems biology D Faller, U Klingmüller, J Timmer Simulation 79 (12), 717-725, 2003 | 188 | 2003 |
| Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2 F Grebien, MA Kerenyi, B Kovacic, T Kolbe, V Becker, H Dolznig, K Pfeffer, ... Blood, The Journal of the American Society of Hematology 111 (9), 4511-4522, 2008 | 176 | 2008 |
| Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1 M Kortylewski, PC Heinrich, A Mackiewicz, U Schniertshauer, ... Oncogene 18 (25), 3742-3753, 1999 | 174 | 1999 |
| The glucocorticoid receptor controls hepatic dyslipidemia through Hes1 U Lemke, A Krones-Herzig, MB Diaz, P Narvekar, A Ziegler, ... Cell metabolism 8 (3), 212-223, 2008 | 167 | 2008 |
| Cellular signal processing: an introduction to the molecular mechanisms of signal transduction F Marks, U Klingmüller, K Müller-Decker Garland Science, 2017 | 164 | 2017 |
