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Guido Marcucci
Guido Marcucci
Verifisert e-postadresse på coh.org
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Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
RM Stone, SJ Mandrekar, BL Sanford, K Laumann, S Geyer, ...
New England Journal of Medicine 377 (5), 454-464, 2017
23952017
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
M Fabbri, R Garzon, A Cimmino, Z Liu, N Zanesi, E Callegari, S Liu, ...
Proceedings of the National Academy of Sciences 104 (40), 15805-15810, 2007
20462007
Targeting microRNAs in cancer: rationale, strategies and challenges
R Garzon, G Marcucci, CM Croce
Nature reviews Drug discovery 9 (10), 775-789, 2010
18612010
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia
KG Roberts, Y Li, D Payne-Turner, RC Harvey, YL Yang, D Pei, ...
New England journal of medicine 371 (11), 1005-1015, 2014
15732014
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia …
G Marcucci, K Maharry, YZ Wu, MD Radmacher, K Mrózek, D Margeson, ...
Journal of clinical oncology 28 (14), 2348-2355, 2010
9912010
R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling
R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ...
Cell 172 (1), 90-105. e23, 2018
9872018
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly …
R Garzon, S Liu, M Fabbri, Z Liu, CEA Heaphy, E Callegari, S Schwind, ...
Blood, The Journal of the American Society of Hematology 113 (25), 6411-6418, 2009
9352009
METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification
H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ...
Cell stem cell 22 (2), 191-205. e9, 2018
8932018
Adverse Prognostic Significance of KIT Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study
P Paschka, G Marcucci, AS Ruppert, K Mrózek, H Chen, RA Kittles, ...
Journal of Clinical Oncology 24 (24), 3904-3911, 2006
8672006
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
R Garzon, S Volinia, CG Liu, C Fernandez-Cymering, T Palumbo, ...
Blood, The Journal of the American Society of Hematology 111 (6), 3183-3189, 2008
8422008
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular …
K Mrózek, G Marcucci, P Paschka, SP Whitman, CD Bloomfield
Blood 109 (2), 431-448, 2007
8122007
Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications
G Marcucci, T Haferlach, H Döhner
Journal of Clinical Oncology 29 (5), 475-486, 2011
7812011
Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia
R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ...
Cancer discovery 4 (3), 362-375, 2014
7652014
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts
AM Eiring, JG Harb, P Neviani, C Garton, JJ Oaks, R Spizzo, S Liu, ...
Cell 140 (5), 652-665, 2010
7132010
Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine
W Blum, R Garzon, RB Klisovic, S Schwind, A Walker, S Geyer, S Liu, ...
Proceedings of the National Academy of Sciences 107 (16), 7473-7478, 2010
6062010
MicroRNA fingerprints during human megakaryocytopoiesis
R Garzon, F Pichiorri, T Palumbo, R Iuliano, A Cimmino, R Aqeilan, ...
Proceedings of the National Academy of Sciences 103 (13), 5078-5083, 2006
6032006
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein
P Neviani, R Santhanam, R Trotta, M Notari, BW Blaser, S Liu, H Mao, ...
Cancer cell 8 (5), 355-368, 2005
6032005
Targeting FTO suppresses cancer stem cell maintenance and immune evasion
R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ...
Cancer cell 38 (1), 79-96. e11, 2020
5932020
MicroRNA 29b functions in acute myeloid leukemia
R Garzon, CEA Heaphy, V Havelange, M Fabbri, S Volinia, T Tsao, ...
Blood, The Journal of the American Society of Hematology 114 (26), 5331-5341, 2009
5672009
Prognostic significance of the European LeukemiaNet standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia
K Mrózek, G Marcucci, D Nicolet, KS Maharry, H Becker, SP Whitman, ...
Journal of clinical oncology 30 (36), 4515-4523, 2012
5512012
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