The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids M Kessler, K Hoffmann, V Brinkmann, O Thieck, S Jackisch, B Toelle, ... Nature communications 6 (1), 8989, 2015 | 461 | 2015 |
Stable expansion of high‐grade serous ovarian cancer organoids requires a low‐Wnt environment K Hoffmann, H Berger, H Kulbe, S Thillainadarasan, HJ Mollenkopf, ... The EMBO journal 39 (6), e104013, 2020 | 148 | 2020 |
The Helicobacter pylori virulence effector CagA abrogates human β-defensin 3 expression via inactivation of EGFR signaling B Bauer, E Pang, C Holland, M Kessler, S Bartfeld, TF Meyer Cell host & microbe 11 (6), 576-586, 2012 | 104 | 2012 |
Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation M Kessler, K Hoffmann, K Fritsche, V Brinkmann, HJ Mollenkopf, O Thieck, ... Nature communications 10 (1), 1194, 2019 | 99 | 2019 |
Chlamydia infection depends on a functional MDM2-p53 axis E González, M Rother, MC Kerr, MA Al-Zeer, M Abu-Lubad, M Kessler, ... Nature communications 5 (1), 5201, 2014 | 90 | 2014 |
Chlamydia trachomatis disturbs epithelial tissue homeostasis in fallopian tubes via paracrine Wnt signaling M Kessler, J Zielecki, O Thieck, HJ Mollenkopf, C Fotopoulou, TF Meyer The American journal of pathology 180 (1), 186-198, 2012 | 84 | 2012 |
The molecular fingerprint of high grade serous ovarian cancer reflects its fallopian tube origin M Kessler, C Fotopoulou, T Meyer International journal of molecular sciences 14 (4), 6571-6596, 2013 | 67 | 2013 |
Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II MA Al-Zeer, A Xavier, MA Lubad, J Sigulla, M Kessler, R Hurwitz, ... EBioMedicine 23, 100-110, 2017 | 57 | 2017 |
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages K Hönzke, B Obermayer, C Mache, D Fatykhova, M Kessler, S Dökel, ... European Respiratory Journal 60 (6), 2022 | 49 | 2022 |
Exploring the clonal evolution of CD133/aldehyde-dehydrogenase-1 (ALDH1)-positive cancer stem-like cells from primary to recurrent high-grade serous ovarian cancer (HGSOC). A … I Ruscito, DC Castillo-Tong, I Vergote, I Ignat, M Stanske, ... European Journal of Cancer 79, 214-225, 2017 | 38 | 2017 |
The prognostic impact of cancer stem-like cell biomarker aldehyde dehydrogenase-1 (ALDH1) in ovarian cancer: A meta-analysis I Ruscito, S Darb-Esfahani, H Kulbe, F Bellati, IG Zizzari, HR Koshkaki, ... Gynecologic Oncology 150 (1), 151-157, 2018 | 33 | 2018 |
Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier A Faist, S Schloer, A Mecate-Zambrano, J Janowski, A Schreiber, ... Antiviral research 209, 105475, 2023 | 31 | 2023 |
Characterisation of tumour microvessel density during progression of high-grade serous ovarian cancer: clinico-pathological impact (an OCTIPS Consortium study). I Ruscito, D Cacsire Castillo-Tong, I Vergote, I Ignat, M Stanske, ... British journal of cancer 119 (3), 330-338, 2018 | 22 | 2018 |
Human alveolar progenitors generate dual lineage bronchioalveolar organoids K Hoffmann, B Obermayer, K Hönzke, D Fatykhova, Z Demir, A Löwa, ... Communications biology 5 (1), 875, 2022 | 17 | 2022 |
Role of FoxP3-positive regulatory T-cells in regressive and progressive cervical dysplasia A Vattai, N Kremer, S Meister, S Beyer, L Keilmann, A Hester, M Temelkov, ... Journal of cancer research and clinical oncology 148 (2), 377-386, 2022 | 13 | 2022 |
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but strong virus-induced immune activation in alveolar macrophages K Hönzke, B Obermayer, C Mache, D Fatykhova, M Kessler, S Dökel, ... | 10 | 2020 |
High RIG-I and EFTUD2 expression predicts poor survival in endometrial cancer S Beyer, L Müller, S Mitter, L Keilmann, S Meister, C Buschmann, F Kraus, ... Journal of Cancer Research and Clinical Oncology 149 (8), 4293-4303, 2023 | 9 | 2023 |
A combination of immunohistochemical markers, MUC1, MUC5AC, PAX8 and growth pattern for characterization of mucinous neoplasm of the ovary A Chelariu-Raicu, E Holley, D Mayr, F Klauschen, F Wehweck, ... International Journal of Gynecological Cancer 32 (5), 662-668, 2022 | 9 | 2022 |
Presence of regulatory T-cells in endometrial cancer predicts poorer overall survival and promotes progression of tumor cells T Kolben, M Mannewitz, C Perleberg, K Schnell, D Anz, L Hahn, S Meister, ... Cellular Oncology 45 (6), 1171-1185, 2022 | 8 | 2022 |
Blood group antigens SLeX, SLeA, and LeY as prognostic markers in endometrial cancer T Kolben, L Müller, S Meister, L Keilmann, C Buschmann, F Trillsch, ... Journal of Cancer Research and Clinical Oncology 148 (12), 3323-3335, 2022 | 8 | 2022 |