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Ambuja Navalkar
Ambuja Navalkar
DST-INSPIRE Faculty, National Centre for Cell Science, Pune, India
Verifisert e-postadresse på nccs.res.in
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α-Synuclein aggregation nucleates through liquid–liquid phase separation
S Ray, N Singh, R Kumar, K Patel, S Pandey, D Datta, J Mahato, ...
Nature Chemistry 12 (8), 705-716, 2020
6662020
p53 amyloid formation leading to its loss of function: implications in cancer pathogenesis
S Ghosh, S Salot, S Sengupta, A Navalkar, D Ghosh, R Jacob, S Das, ...
Cell Death & Differentiation 24 (10), 1784-1798, 2017
1352017
Lipopolysaccharide from gut microbiota modulates α-synuclein aggregation and alters its biological function
D Bhattacharyya, GM Mohite, J Krishnamoorthy, N Gayen, S Mehra, ...
ACS chemical neuroscience 10 (5), 2229-2236, 2019
1042019
Intermolecular interactions underlie protein/peptide phase separation irrespective of sequence and structure at crowded milieu
M Poudyal, K Patel, L Gadhe, AS Sawner, P Kadu, D Datta, S Mukherjee, ...
Nature communications 14 (1), 6199, 2023
80*2023
Comparison of α-synuclein fibril inhibition by four different amyloid inhibitors
NN Jha, R Kumar, R Panigrahi, A Navalkar, D Ghosh, S Sahay, M Mondal, ...
ACS chemical neuroscience 8 (12), 2722-2733, 2017
672017
Fabrication of silver nanowire/polydimethylsiloxane dry electrodes by a vacuum filtration method for electrophysiological signal monitoring
RR Kisannagar, P Jha, A Navalkar, SK Maji, D Gupta
ACS omega 5 (18), 10260-10265, 2020
642020
Prion-like p53 amyloids in cancer
A Navalkar, S Ghosh, S Pandey, A Paul, D Datta, SK Maji
Biochemistry 59 (2), 146-155, 2019
622019
Comparison of kinetics, toxicity, oligomer formation, and membrane binding capacity of α-synuclein familial mutations at the A53 site, including the newly discovered A53V mutation
GM Mohite, R Kumar, R Panigrahi, A Navalkar, N Singh, D Datta, S Mehra, ...
Biochemistry 57 (35), 5183-5187, 2018
542018
Phenylselenyl containing turn-on dibodipy probe for selective detection of superoxide in mammalian breast cancer cell line
PP Deshmukh, A Navalkar, SK Maji, ST Manjare
Sensors and Actuators B: Chemical 281, 8-13, 2019
362019
MYC phase separation selectively modulates the transcriptome
J Yang, CI Chung, J Koach, H Liu, A Navalkar, H He, Z Ma, Q Zhao, ...
Nature Structural & Molecular Biology 31 (10), 1567-1579, 2024
30*2024
Direct evidence of cellular transformation by prion-like p53 amyloid infection
A Navalkar, S Pandey, N Singh, K Patel, D Datta, B Mohanty, S Jadhav, ...
Journal of Cell Science 134 (11), jcs258316, 2021
28*2021
Organoselenium-based BOPHY as a sensor for detection of hypochlorous acid in mammalian cells
GS Malankar, A Sakunthala, A Navalkar, SK Maji, S Raju, ST Manjare
Analytica Chimica Acta 1150, 338205, 2021
262021
The familial α-synuclein A53E mutation enhances cell death in response to environmental toxins due to a larger population of oligomers
GM Mohite, A Navalkar, R Kumar, S Mehra, S Das, LG Gadhe, D Ghosh, ...
Biochemistry 57 (33), 5014-5028, 2018
242018
α-Synuclein aggregation intermediates form fibril polymorphs with distinct prion-like properties
S Mehra, S Ahlawat, H Kumar, D Datta, A Navalkar, N Singh, K Patel, ...
Journal of Molecular Biology 434 (19), 167761, 2022
222022
Biophysical characterization of p53 core domain aggregates
I Lima, A Navalkar, SK Maji, JL Silva, GAP de Oliveira, EA Cino
Biochemical Journal 477 (1), 111-120, 2020
212020
Cyclic organoselenide BODIPY-based probe: targeting superoxide in MCF-7 cancer cells
KS Madibone, PP Deshmukh, A Navalkar, SK Maji, PM Badani, ...
ACS omega 5 (23), 14186-14193, 2020
202020
Co-aggregation and secondary nucleation in the life cycle of human prolactin/galanin functional amyloids
D Chatterjee, RS Jacob, S Ray, A Navalkar, N Singh, S Sengupta, ...
Elife 11, e73835, 2022
172022
Oncogenic gain of function due to p53 amyloids occurs through aberrant alteration of cell cycle and proliferation
A Navalkar, A Paul, A Sakunthala, S Pandey, AK Dey, S Saha, S Sahoo, ...
Journal of cell science 135 (15), jcs259500, 2022
162022
Amyloid fibril-based thixotropic hydrogels for modeling of tumor spheroids in vitro
N Singh, K Patel, A Navalkar, P Kadu, D Datta, D Chatterjee, S Mukherjee, ...
Biomaterials 295, 122032, 2023
15*2023
Direct demonstration of seed size-dependent α-synuclein amyloid amplification
A Sakunthala, D Datta, A Navalkar, L Gadhe, P Kadu, K Patel, S Mehra, ...
The journal of physical chemistry letters 13 (28), 6427-6438, 2022
15*2022
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