| Modeling and simulation of biological systems with stochasticity TC Meng, S Somani, P Dhar In Silico Biology 4 (3), 293-309, 2004 | 206 | 2004 |
| Configurational Entropy in Protein–Peptide Binding:: Computational Study of Tsg101 Ubiquitin E2 Variant Domain with an HIV-Derived PTAP Nonapeptide BJ Killian, JY Kravitz, S Somani, P Dasgupta, YP Pang, MK Gilson Journal of molecular biology 389 (2), 315-335, 2009 | 101 | 2009 |
| Cellware—a multi-algorithmic software for computational systems biology P Dhar, TC Meng, S Somani, L Ye, A Sairam, M Chitre, Z Hao, ... Bioinformatics 20 (8), 1319-1321, 2004 | 80 | 2004 |
| Homology‐based hydrogen bond information improves crystallographic structures in the PDB B van Beusekom, WG Touw, M Tatineni, S Somani, G Rajagopal, J Luo, ... Protein Science 27 (3), 798-808, 2018 | 60 | 2018 |
| Grid cellware: the first grid-enabled tool for modelling and simulating cellular processes PK Dhar, TC Meng, S Somani, L Ye, K Sakharkar, A Krishnan, ... Bioinformatics 21 (7), 1284-1287, 2005 | 55 | 2005 |
| Functional, biophysical, and structural characterization of human IgG1 and IgG4 Fc variants with ablated immune functionality SH Tam, SG McCarthy, AA Armstrong, S Somani, SJ Wu, X Liu, A Gervais, ... Antibodies 6 (3), 12, 2017 | 51 | 2017 |
| Efficient generation of bispecific murine antibodies for pre-clinical investigations in syngeneic rodent models AF Labrijn, JI Meesters, M Bunce, AA Armstrong, S Somani, TC Nesspor, ... Scientific reports 7 (1), 2476, 2017 | 47 | 2017 |
| Exploiting the potential energy landscape to sample free energy AJ Ballard, S Martiniani, JD Stevenson, S Somani, DJ Wales Wiley Interdisciplinary Reviews: Computational Molecular Science 5 (3), 273-289, 2015 | 36 | 2015 |
| Computational characterization of antibody–excipient interactions for rational excipient selection using the site identification by ligand competitive saturation-biologics approach S Jo, A Xu, JE Curtis, S Somani, AD MacKerell Jr Molecular pharmaceutics 17 (11), 4323-4333, 2020 | 27 | 2020 |
| A conformational factorisation approach for estimating the binding free energies of macromolecules K Mochizuki, CS Whittleston, S Somani, H Kusumaatmaja, DJ Wales Physical Chemistry Chemical Physics 16 (7), 2842-2853, 2014 | 27 | 2014 |
| Hydration of a hydrophobic cavity and its functional role: a simulation study of human interleukin‐1β S Somani, CP Chng, CS Verma Proteins: Structure, Function, and Bioinformatics 67 (4), 868-885, 2007 | 26 | 2007 |
| Energy landscapes and global thermodynamics for alanine peptides S Somani, DJ Wales The Journal of Chemical Physics 139 (12), 2013 | 22 | 2013 |
| Sampling conformations in high dimensions using low-dimensional distribution functions S Somani, BJ Killian, MK Gilson The Journal of chemical physics 130 (13), 2009 | 20 | 2009 |
| Product-specific impact of viscosity modulating formulation excipients during ultra-high concentration biotherapeutics drug product development D Rodrigues, LM Tanenbaum, R Thirumangalathu, S Somani, K Zhang, ... Journal of Pharmaceutical Sciences 110 (3), 1077-1082, 2021 | 17 | 2021 |
| Toward biotherapeutics formulation composition engineering using site-identification by ligand competitive saturation (SILCS) S Somani, S Jo, R Thirumangalathu, D Rodrigues, LM Tanenbaum, ... Journal of pharmaceutical sciences 110 (3), 1103-1110, 2021 | 17 | 2021 |
| Surface salt bridges contribute to the extreme thermal stability of an FN3‐like domain from a thermophilic bacterium L Boucher, S Somani, C Negron, W Ma, S Jacobs, W Chan, T Malia, ... Proteins: Structure, Function, and Bioinformatics 90 (1), 270-281, 2022 | 9 | 2022 |
| Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing RE Matico, X Yu, R Miller, S Somani, MD Ricketts, N Kumar, RA Steele, ... Nature Structural & Molecular Biology 31 (1), 82-91, 2024 | 8 | 2024 |
| Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases C Sun, BT Frederick, S Somani, GT Bourne, R Patch, A Bhandari US Patent 11,845,808, 2023 | 8 | 2023 |
| Accelerated convergence of molecular free energy via superposition approximation-based reference states S Somani, MK Gilson The Journal of chemical physics 134 (13), 2011 | 6 | 2011 |
| Cyclic peptide linker design and optimization by molecular dynamics simulations L Yu, SA Barros, C Sun, S Somani Journal of Chemical Information and Modeling 63 (21), 6863-6876, 2023 | 5 | 2023 |
Michael K GilsonUniversity of California San DiegoVerifisert e-postadresse på health.ucsd.edu