| De novo design of luciferases using deep learning AHW Yeh, C Norn, Y Kipnis, D Tischer, SJ Pellock, D Evans, P Ma, ... Nature 614 (7949), 774-780, 2023 | 284 | 2023 |
| Phase separation of a PKA regulatory subunit controls cAMP compartmentation and oncogenic signaling JZ Zhang, TW Lu, LM Stolerman, B Tenner, JR Yang, JF Zhang, M Falcke, ... Cell 182 (6), 1531-1544. e15, 2020 | 255 | 2020 |
| An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice JF Zhang*, B Liu*, I Hong*, A Mo, RH Roth, B Tenner, W Lin, JZ Zhang, ... Nature chemical biology 17 (1), 39-46, 2021 | 83 | 2021 |
| Liquid–liquid phase separation: a principal organizer of the cell’s biochemical activity architecture JZ Zhang, S Mehta, J Zhang Trends in pharmacological sciences 42 (10), 845-856, 2021 | 40 | 2021 |
| Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants JZ Zhang*, HW Yeh*, AC Walls, BIM Wicky, KR Sprouse, LA VanBlargan, ... Nature Biotechnology, 1-5, 2022 | 30 | 2022 |
| FluoSTEPs: Fluorescent biosensors for monitoring compartmentalized signaling within endogenous microdomains B Tenner*, JZ Zhang*, Y Kwon, V Pessino, S Feng, B Huang, S Mehta, ... Science Advances 7 (21), eabe4091, 2021 | 27 | 2021 |
| Designed endocytosis-inducing proteins degrade targets and amplify signals B Huang, M Abedi, G Ahn, B Coventry, I Sappington, C Tang, R Wang, ... Nature, 1-9, 2024 | 15* | 2024 |
| Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution JZ Zhang, WH Nguyen, N Greenwood, JC Rose, SE Ong, DJ Maly, ... Nature Biotechnology 42 (12), 1888-1898, 2024 | 11* | 2024 |
| Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling JZ Zhang, AH Nguyen, S Miyamoto, J Heller Brown, AD McCulloch, ... PLoS Biology 18 (9), e3000866, 2020 | 10 | 2020 |
| Computational design of non-porous pH-responsive antibody nanoparticles EC Yang, R Divine, MC Miranda, AJ Borst, W Sheffler, JZ Zhang, ... Nature structural & molecular biology 31 (9), 1404-1412, 2024 | 8 | 2024 |
| Characterizing protein kinase A (PKA) subunits as macromolecular regulators of PKA RI α liquid–liquid phase separation SH Ahn*, S Qin*, JZ Zhang, JA McCammon, J Zhang, HX Zhou The Journal of Chemical Physics 154 (22), 221101, 2021 | 7 | 2021 |
| Single-cell sensor analyses reveal signaling programs enabling Ras-G12C drug resistance JZ Zhang, SE Ong, D Baker, DJ Maly Nature Chemical Biology, 1-12, 2024 | 2* | 2024 |
| De novo designed Hsp70 activator dissolves intracellular condensates JZ Zhang, N Greenwood, J Hernandez, JT Cuperus, B Huang, BD Ryder, ... Cell Chemical Biology, 2023 | 2 | 2023 |
| Protocol for using fluorescent sensors targeted to endogenous proteins (FluoSTEPs) to measure microdomain-specific signaling events JZ Zhang, B Tenner, S Mehta, J Zhang STAR protocols 2 (3), 100693, 2021 | 2 | 2021 |
| De novo design of Ras isoform selective binders JZ Zhang, X Li, AR Batingana, C Liu, H Jiang, K Shannon, BJ Huang, ... bioRxiv, 2024.08. 29.610300, 2024 | 1 | 2024 |
| Automated, miniaturized, and scalable screening of healthcare workers, first responders, and students for SARS-CoV-2 in San Diego County SC Morgan, S Aigner, C Anderson, P Belda-Ferre, P De Hoff, CA Marotz, ... medRxiv, 2021.06. 25.21257885, 2021 | 1 | 2021 |
Jin ZhangUniversity of California, San DiegoVerifisert e-postadresse på ucsd.edu