| miRTarBase update 2022: an informative resource for experimentally validated miRNA–target interactions HY Huang, YCD Lin, S Cui, Y Huang, Y Tang, J Xu, J Bao, Y Li, J Wen, ... Nucleic acids research 50 (D1), D222-D230, 2022 | 678 | 2022 |
| Constructing Markov State Models to elucidate the functional conformational changes of complex biomolecules W Wang, S Cao, L Zhu, X Huang Wiley Interdisciplinary Reviews: Computational Molecular Science 6, e1343, 2017 | 151 | 2017 |
| Unraveling the aggregation effect on amorphous phase AIE luminogens: a computational study X Zheng, Q Peng, L Zhu, Y Xie, X Huang, Z Shuai Nanoscale 8 (33), 15173-15180, 2016 | 134 | 2016 |
| dbAMP 2.0: updated resource for antimicrobial peptides with an enhanced scanning method for genomic and proteomic data JH Jhong, L Yao, Y Pang, Z Li, CR Chung, R Wang, S Li, W Li, M Luo, ... Nucleic acids research 50 (D1), D460-D470, 2022 | 118 | 2022 |
| Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes P Xiao, W Yan, L Gou, YN Zhong, L Kong, C Wu, X Wen, Y Yuan, S Cao, ... Cell 184 (4), 943-956. e18, 2021 | 118 | 2021 |
| A deep learning framework to predict binding preference of RNA constituents on protein surface JH Lam, Y Li, L Zhu, R Umarov, H Jiang, A Héliou, FK Sheong, T Liu, ... Nature communications 10 (1), 4941, 2019 | 104 | 2019 |
| Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo G Luo, Z Li, X Lin, X Li, Y Chen, K Xi, M Xiao, H Wei, L Zhu, H Xiang Acta Pharmaceutica Sinica B 11 (5), 1300-1314, 2021 | 65 | 2021 |
| Markov state models reveal a two-step mechanism of miRNA loading into the human argonaute protein: selective binding followed by structural re-arrangement H Jiang, FK Sheong, L Zhu, X Gao, J Bernauer, X Huang PLoS computational biology 11 (7), e1004404, 2015 | 63 | 2015 |
| Structural insights into sphingosine-1-phosphate receptor activation L Yu, L He, B Gan, R Ti, Q Xiao, X Yang, H Hu, L Zhu, S Wang, R Ren Proceedings of the National Academy of Sciences 119 (16), e2117716119, 2022 | 43 | 2022 |
| Adaptive partitioning by local density‐peaks: An efficient density‐based clustering algorithm for analyzing molecular dynamics trajectories S Liu, L Zhu, FK Sheong, W Wang, X Huang Journal of Computational Chemistry 38 (3), 152-160, 2017 | 41 | 2017 |
| Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism Y Han, Q Zhuang, B Sun, W Lv, S Wang, Q Xiao, B Pang, Y Zhou, F Wang, ... Nature communications 12 (1), 449, 2021 | 40 | 2021 |
| Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns G Chen, X Wang, Q Liao, Y Ge, H Jiao, Q Chen, Y Liu, W Lyu, L Zhu, ... Nature communications 13 (1), 5232, 2022 | 35 | 2022 |
| Kinetics-controlled amphiphile self-assembly processes X Zheng, L Zhu, X Zeng, L Meng, L Zhang, D Wang, X Huang The Journal of Physical Chemistry Letters 8 (8), 1798-1803, 2017 | 33 | 2017 |
| Molecular mechanisms of RNA polymerase II transcription elongation elucidated by kinetic network models IC Unarta, L Zhu, CKM Tse, PPH Cheung, J Yu, X Huang Current Opinion in Structural Biology 49, 54-62, 2018 | 30 | 2018 |
| Single-molecule investigations of conformation adaptation of porphyrins on surfaces Q Zhang, X Zheng, G Kuang, W Wang, L Zhu, R Pang, X Shi, X Shang, ... The journal of physical chemistry letters 8 (6), 1241-1247, 2017 | 29 | 2017 |
| Elucidating dominant pathways of the nano-particle self-assembly process X Zeng, B Li, Q Qiao, L Zhu, ZY Lu, X Huang Physical Chemistry Chemical Physics 18 (34), 23494-23499, 2016 | 26 | 2016 |
| TAPS: A traveling-salesman based automated path searching method for functional conformational changes of biological macromolecules L Zhu, FK Sheong, S Cao, S Liu, IC Unarta, X Huang The Journal of Chemical Physics 150 (12), 2019 | 22 | 2019 |
| A Flexible Domain-Domain Hinge Promotes an Induced-fit Dominant Mechanism for the Loading of Guide-DNA into Argonaute Protein in Thermus thermophilus L Zhu, H Jiang, FK Sheong, X Cui, X Gao, Y Wang, X Huang The Journal of Physical Chemistry B 120 (10), 2709-2720, 2016 | 22 | 2016 |
| Elucidation of the conformational dynamics of multi-body systems by construction of Markov state models L Zhu, FK Sheong, X Zeng, X Huang Physical Chemistry Chemical Physics 18 (44), 30228-30235, 2016 | 22 | 2016 |
| Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk M Bratkowski, IC Unarta, L Zhu, M Shubbar, X Huang, X Liu Journal of Biological Chemistry 293 (5), 1651-1665, 2018 | 18 | 2018 |
Xuhui HuangHirschfelder Chair in Theoretical Chemistry, University of Wisconsin-Madison (previously at HKUST)Verifisert e-postadresse på chem.wisc.edu
