The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin C Batandier, B Guigas, D Detaille, M El-Mir, E Fontaine, M Rigoulet, ... Journal of bioenergetics and biomembranes 38, 33-42, 2006 | 370 | 2006 |
Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway AI Morales, D Detaille, M Prieto, A Puente, E Briones, M Arévalo, ... Kidney international 77 (10), 861-869, 2010 | 363 | 2010 |
Metformin prevents high-glucose–induced endothelial cell death through a mitochondrial permeability transition-dependent process D Detaille, B Guigas, C Chauvin, C Batandier, E Fontaine, ... Diabetes 54 (7), 2179-2187, 2005 | 339 | 2005 |
Role of mitochondria in the mechanism (s) of action of metformin G Vial, D Detaille, B Guigas Frontiers in endocrinology 10, 294, 2019 | 299 | 2019 |
Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons MY El-Mir, D Detaille, G R-Villanueva, M Delgado-Esteban, B Guigas, ... Journal of Molecular Neuroscience 34, 77-87, 2008 | 297 | 2008 |
Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study B Guigas, D Detaille, C Chauvin, C Batandier, F De Oliveira, E Fontaine, ... Biochemical journal 382 (3), 877-884, 2004 | 194 | 2004 |
Mitochondrial metabolism and type-2 diabetes: a specific target of metformin XM Leverve, B Guigas, D Detaille, C Batandier, EA Koceir, C Chauvin, ... Diabetes & metabolism 29 (4), 6S88-6S94, 2003 | 193 | 2003 |
Mitochondrial energetics is impaired in vivo in aged skeletal muscle G Gouspillou, I Bourdel‐Marchasson, R Rouland, G Calmettes, M Biran, ... Aging cell 13 (1), 39-48, 2014 | 152 | 2014 |
AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside B Guigas, N Taleux, M Foretz, D Detaille, F Andreelli, B Viollet, L Hue Biochemical Journal 404 (3), 499-507, 2007 | 128 | 2007 |
Obligatory role of membrane events in the regulatory effect of metformin on the respiratory chain function D Detaille, B Guigas, X Leverve, N Wiernsperger, P Devos Biochemical pharmacology 63 (7), 1259-1272, 2002 | 124 | 2002 |
Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes D Detaille, C Sanchez, N Sanz, JM Lopez-Novoa, X Leverve, MY El-Mir Life sciences 82 (21-22), 1070-1076, 2008 | 97 | 2008 |
Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration D Detaille, G Vial, AL Borel, C Cottet-Rouselle, S Hallakou-Bozec, ... Cell death discovery 2 (1), 1-8, 2016 | 88 | 2016 |
Effect of transient and permanent permeability transition pore opening on NAD (P) H localization in intact cells JF Dumas, L Argaud, C Cottet-Rousselle, G Vial, C Gonzalez, D Detaille, ... Journal of Biological Chemistry 284 (22), 15117-15125, 2009 | 61 | 2009 |
Beneficial effects of silibinin against the progression of metabolic syndrome, increased oxidative stress, and liver steatosis in Psammomys obesus, a relevant … S Bouderba, C Sanchez‐Martin, GR Villanueva, D Detaille, EA Koceïr Journal of diabetes 6 (2), 184-192, 2014 | 57 | 2014 |
An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals D Detaille, P Pasdois, A Sémont, P Dos Santos, P Diolez PLoS One 14 (5), e0216385, 2019 | 50 | 2019 |
Impact of afterload increase on left ventricular myocardial deformation indices P Reant, A Metras, D Detaille, A Reynaud, P Diolez, B Jaspard-Vinassa, ... Journal of the American Society of Echocardiography 29 (12), 1217-1228, 2016 | 43 | 2016 |
Hepatic Mitochondrial Alterations and Increased Oxidative Stress in Nutritional Diabetes‐Prone Psammomys obesus Model S Bouderba, MN Sanz, C Sánchez-Martín, MY El-Mir, GR Villanueva, ... Journal of Diabetes Research 2012 (1), 430176, 2012 | 40 | 2012 |
Acute mitochondrial actions of glitazones on the liver: a crucial parameter for their antidiabetic properties MN Sanz, C Sánchez-Martín, D Detaille, G Vial, M Rigoulet, MY El-Mir, ... Cellular physiology and biochemistry 28 (5), 899-910, 2011 | 28 | 2011 |
The desert gerbil Psammomys obesus as a model for metformin-sensitive nutritional type 2 diabetes to protect hepatocellular metabolic damage: Impact of … I Gouaref, D Detaille, N Wiernsperger, NA Khan, X Leverve, EA Koceir PLoS One 12 (2), e0172053, 2017 | 26 | 2017 |
Compartmentalized structure of the moderator band provides a unique substrate for macroreentrant ventricular tachycardia RD Walton, A Pashaei, ME Martinez, M Constantin, J Duchateau, L Bear, ... Circulation: Arrhythmia and Electrophysiology 11 (8), e005913, 2018 | 25 | 2018 |