IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex J Davila-Calderon, NN Patwardhan, LY Chiu, A Sugarman, Z Cai, ... Nature communications 11 (1), 4775, 2020 | 92 | 2020 |
Structural insights into calcium-bound S100P and the V domain of the RAGE complex SR Penumutchu, RH Chou, C Yu PloS one 9 (8), e103947, 2014 | 61 | 2014 |
Genome-wide analysis of heterogeneous nuclear ribonucleoprotein (hnRNP) binding to HIV-1 RNA reveals a key role for hnRNP H1 in alternative viral mRNA splicing SB Kutluay, A Emery, SR Penumutchu, D Townsend, K Tenneti, ... Journal of virology 93 (21), 10.1128/jvi. 01048-19, 2019 | 36 | 2019 |
Nanoparticle based simple electrochemical biosensor platform for profiling of protein-nucleic acid interactions CCL Yifan Dai a b 1 , Liang-Yuan Chiu c 1 , Yongkun Sui d , Quanbin Dai e ... Talanta 195, Pages 46-54, 2019 | 23 | 2019 |
Differential Conformational Dynamics Encoded by the Linker between Quasi RNA Recognition Motifs of Heterogeneous Nuclear Ribonucleoprotein H SR Penumutchu, LY Chiu, JL Meagher, AL Hansen, JA Stuckey, ... Journal of the American Chemical Society 140 (37), 11661-11673, 2018 | 16 | 2018 |
Interaction between S100P and the anti-allergy drug cromolyn SR Penumutchu, RH Chou, C Yu Biochemical and biophysical research communications 454 (3), 404-409, 2014 | 15 | 2014 |
A structurally conserved RNA element within SARS-CoV-2 ORF1a RNA and S mRNA regulates translation in response to viral S protein-induced signaling in human lung cells A Basu, S Penumutchu, K Nguyen, U Mbonye, BS Tolbert, J Karn, ... Journal of Virology 96 (2), e01678-21, 2022 | 10 | 2022 |
Phosphomimetic substitutions in TDP-43’s transiently α-helical region suppress phase separation R Haider, S Penumutchu, S Boyko, WK Surewicz Biophysical Journal 123 (3), 361-373, 2024 | 9 | 2024 |
Thermodynamic Coupling of the tandem RRM domains of hnRNP A1 underlie its Pleiotropic RNA Binding Functions JD Levengood, D Potoyan, S Penumutchu, A Kumar, Y Wang, AL Hansen, ... Sci. Adv.10, eadk 6580(2024), 2024 | 6 | 2024 |
Enterovirus evolution reveals the mechanism of an RNA-targeted antiviral and determinants of viral replication J Davila-Calderon, ML Li, SR Penumutchu, C Haddad, L Malcolm, J King, ... Science Advances 10 (7), eadg3060, 2024 | 5 | 2024 |
Alternatively spliced CSF3R isoforms in SRSF2 P95H mutated myeloid neoplasms BA Wang, HM Mehta, SR Penumutchu, BS Tolbert, C Cheng, M Kimmel, ... Leukemia 36 (10), 2499-2508, 2022 | 5 | 2022 |
Design, synthesis, molecular docking and cytotoxic activity of novel urea derivatives of 2-amino-3-carbomethoxythiophene KRAUP Venugopalarao Vikram, Srinivasa R Penumutchu, Raviraj Vankayala ... Journal of Chemical Sciences 132 (126), 2020 | 4 | 2020 |
1H, 15N and 13C assignments of the calcium bound S100P SR Penumutchu, SK Mohan, C Yu Biomolecular NMR assignments 7, 5-8, 2013 | 4 | 2013 |
The repurposing of cellular proteins during enterovirus A71 infection SM Abedeera, J Davila-Calderon, C Haddad, B Henry, J King, ... Viruses 16 (1), 75, 2023 | 2 | 2023 |
Backbone resonance assignments of the PRYSPRY domain of TRIM25 C Kong, SR Penumutchu, K Hung, H Huang, T Lin, C Yu Biomolecular NMR assignments 9, 313-315, 2015 | 2 | 2015 |
Protocol to identify drug-binding sites in proteins using solution NMR spectroscopy S Penumutchu, J Liu, UK Singh, TG Kutateladze, Y Zhang STAR protocols 3 (4), 101842, 2022 | 1 | 2022 |
Small Molecule Targeting IRES Domain Inhibits Enterovirus 71 Replication via an Allosteric Mechanism that Stabilizes a Ternary Complex J Davila-Calderon, N Patwardhan, LY Chiu, A Sugarman, Z Cai, ... bioRxiv, 2020.03. 10.981167, 2020 | 1 | 2020 |
A regulatory interplay: hnRNP A1 and AUF1 compete for the same IRES domain to regulate viral translation in EV71 S Penumutchu, J Calderon, B Tolbert The FASEB Journal 33, 625.5-625.5, 2019 | 1* | 2019 |
Design, synthesis and biological studies of tetrazole fused imidazopyridines. MVBR Banoth Reddy, Amit Kumar Taneja, Mandava Bhuvan Tej, Komati Navya Sri ... Carbon Letters 2024, 34 (1) , 41-49 34 (1), 41-49, 2024 | | 2024 |
Investigating the Interaction of Enterovirus A71 3C Protease and the 5’-Untranslated Region to Highlight Druggable Surfaces BST Christina Haddad1 , Srinivasa Penumutchu1 ICMRBS 2022, 2022 | | 2022 |