| The cellular and synaptic architecture of the mechanosensory dorsal horn VE Abraira, ED Kuehn, AM Chirila, MW Springel, AA Toliver, ... Cell 168 (1), 295-310. e19, 2017 | 397 | 2017 |
| Peripheral mechanosensory neuron dysfunction underlies tactile and behavioral deficits in mouse models of ASDs LL Orefice, AL Zimmerman, AM Chirila, SJ Sleboda, JP Head, DD Ginty Cell 166 (2), 299-313, 2016 | 394 | 2016 |
| BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission EG Waterhouse, JJ An, LL Orefice, M Baydyuk, GY Liao, K Zheng, B Lu, ... Journal of Neuroscience 32 (41), 14318-14330, 2012 | 344 | 2012 |
| Targeting peripheral somatosensory neurons to improve tactile-related phenotypes in ASD models LL Orefice, JR Mosko, DT Morency, MF Wells, A Tasnim, SM Mozeika, ... Cell 178 (4), 867-886. e24, 2019 | 219 | 2019 |
| DeepEthogram, a machine learning pipeline for supervised behavior classification from raw pixels JP Bohnslav, NK Wimalasena, KJ Clausing, YY Dai, DA Yarmolinsky, ... elife 10, e63377, 2021 | 176 | 2021 |
| Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception NL Neubarth, AJ Emanuel, Y Liu, MW Springel, A Handler, Q Zhang, ... Science 368 (6497), eabb2751, 2020 | 128 | 2020 |
| Hypoxia rescues frataxin loss by restoring iron sulfur cluster biogenesis T Ast, JD Meisel, S Patra, H Wang, RMH Grange, SH Kim, SE Calvo, ... Cell 177 (6), 1507-1521. e16, 2019 | 121 | 2019 |
| Distinct roles for somatically and dendritically synthesized brain-derived neurotrophic factor in morphogenesis of dendritic spines LL Orefice, EG Waterhouse, JG Partridge, RR Lalchandani, S Vicini, B Xu Journal of Neuroscience 33 (28), 11618-11632, 2013 | 111 | 2013 |
| Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice CM Chen, LL Orefice, SL Chiu, TA LeGates, S Hattar, RL Huganir, H Zhao, ... Proceedings of the National Academy of Sciences 114 (4), E619-E628, 2017 | 88 | 2017 |
| Control of spine maturation and pruning through proBDNF synthesized and released in dendrites LL Orefice, CC Shih, H Xu, EG Waterhouse, B Xu Molecular and Cellular Neuroscience 71, 66-79, 2016 | 62 | 2016 |
| Peripheral somatosensory neuron dysfunction: emerging roles in autism spectrum disorders LL Orefice Neuroscience 445, 120-129, 2020 | 46 | 2020 |
| Neural, endocrine and electroencephalographic hyperreactivity to human contact: a diathesis-stress model of seizure susceptibility in El mice PA Forcelli, LL Orefice, SC Heinrichs Brain research 1144, 248-256, 2007 | 26 | 2007 |
| Outside-in: rethinking the etiology of autism spectrum disorders LL Orefice Science 366 (6461), 45-46, 2019 | 17 | 2019 |
| The developmental timing of spinal touch processing alterations predicts behavioral changes in genetic mouse models of autism spectrum disorders A Tasnim, I Alkislar, R Hakim, J Turecek, A Abdelaziz, LL Orefice, ... Nature Neuroscience 27 (3), 484-496, 2024 | 12 | 2024 |
| Paternal care paradoxically increases offspring seizure susceptibility in the El mouse model of epilepsy LL Orefice, SC Heinrichs Epilepsy & Behavior 12 (2), 234-241, 2008 | 12 | 2008 |
| Methods and compositions for reducing tactile dysfunction and anxiety associated with autism spectrum disorder, Rett syndrome, and Fragile X syndrome LL Orefice, DD Ginty US Patent 11,547,706, 2023 | 9 | 2023 |
| Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment DD Ginty, LL Orefice, J Lee US Patent App. 17/056,069, 2021 | 5 | 2021 |
| Emerging Therapeutic Strategies for Fragile X Syndrome: Q&A G Alusi, E Berry-Kravis, D Nelson, LL Orefice, SA Booker ACS Chemical Neuroscience 13 (24), 3544-3546, 2022 | 4 | 2022 |
| Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment DD Ginty, LL Orefice, J Lee US Patent 11,434,244, 2022 | 4 | 2022 |
| Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment DD Ginty, LL Orefice, J Lee US Patent 12,077,512, 2024 | 3 | 2024 |