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Andy Hsien-Wei Yeh
Andy Hsien-Wei Yeh
University of California Santa Cruz, Biomolecular Engineering
Verifisert e-postadresse på ucsc.edu - Startside
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De novo design of luciferases using deep learning
AHW Yeh, C Norn, Y Kipnis, D Tischer, SJ Pellock, D Evans, P Ma, ...
Nature 614 (7949), 774-780, 2023
2842023
De novo design of modular and tunable protein biosensors
A Quijano-Rubio, HW Yeh, J Park, H Lee, RA Langan, SE Boyken, ...
Nature 591 (7850), 482-487, 2021
2232021
Red-shifted luciferase–luciferin pairs for enhanced bioluminescence imaging
HW Yeh, O Karmach, A Ji, D Carter, MM Martins-Green, H Ai
Nature methods 14 (10), 971-974, 2017
2032017
Development and Applications of Bioluminescent and Chemiluminescent Reporters and Biosensors
HW Yeh, HW Ai
Annual Review of Analytical Chemistry 12, 129-150, 2019
1792019
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice
AC Hunt, JB Case, YJ Park, L Cao, K Wu, AC Walls, Z Liu, JE Bowen, ...
Science Translational Medicine, eabn1252, 2022
117*2022
De novo design of high-affinity binders of bioactive helical peptides
S Vázquez Torres, PJY Leung, P Venkatesh, ID Lutz, F Hink, HH Huynh, ...
Nature 626 (7998), 435-442, 2024
104*2024
ATP-independent bioluminescent reporter variants to improve in vivo imaging
HW Yeh, Y Xiong, T Wu, M Chen, A Ji, X Li, H Ai
ACS chemical biology 14 (5), 959-965, 2019
632019
Identification of Factors Complicating Bioluminescence Imaging
HW Yeh, T Wu, M Chen, H Ai
Biochemistry 58 (12), 1689-1697, 2019
402019
Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase
XW Zou, YC Liu, NS Hsu, CJ Huang, SY Lyu, HC Chan, CY Chang, ...
Biological Crystallography 70 (6), 1549-1560, 2014
382014
Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants
JZ Zhang, HW Yeh, AC Walls, BIM Wicky, KR Sprouse, LA VanBlargan, ...
Nature biotechnology 40 (9), 1336-1340, 2022
302022
S-Linked sialyloligosaccharides bearing liposomes and micelles as influenza virus inhibitors
HW Yeh, TS Lin, HW Wang, HW Cheng, DZ Liu, PH Liang
Organic & biomolecular chemistry 13 (47), 11518-11528, 2015
262015
Synthesis of a chlorogenin glycoside library using an orthogonal protecting group strategy
YH Wang, HW Yeh, HW Wang, CC Yu, JH Guh, DZ Liu, PH Liang
Carbohydrate Research 375, 118-135, 2013
182013
Synthesis of S-linked NeuAc-α (2-6)-di-LacNAc bearing liposomes for H1N1 influenza virus inhibition assays
HW Cheng, HW Wang, TY Wong, HW Yeh, YC Chen, DZ Liu, PH Liang
Bioorganic & Medicinal Chemistry 26 (9), 2262-2270, 2018
172018
Small-molecule binding and sensing with a designed protein family
GR Lee, SJ Pellock, C Norn, D Tischer, J Dauparas, I Anischenko, ...
bioRxiv, 2023.11. 01.565201, 2023
142023
Synthesis and biological evaluation of novel C-aryl d-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitors
TS Lin, YW Liw, JS Song, TC Hsieh, HW Yeh, LC Hsu, CJ Lin, SH Wu, ...
Bioorganic & medicinal chemistry 21 (21), 6282-6291, 2013
142013
Development, characterization, and structural analysis of a genetically encoded red fluorescent peroxynitrite biosensor
Y Pang, M Huang, Y Fan, HW Yeh, Y Xiong, HL Ng, H Ai
ACS chemical biology 18 (6), 1388-1397, 2023
72023
Biochemical and structural explorations of α-hydroxyacid oxidases reveal a four-electron oxidative decarboxylation reaction
HW Yeh, KH Lin, SY Lyu, YS Li, CM Huang, YL Wang, HW Shih, NS Hsu, ...
Biological Crystallography 75 (8), 733-742, 2019
52019
Structural and chemical trapping of flavin‐oxide intermediates reveals substrate‐directed reaction multiplicity
KH Lin, SY Lyu, HW Yeh, YS Li, NS Hsu, CM Huang, YL Wang, HW Shih, ...
Protein Science 29 (7), 1655-1666, 2020
32020
The flavin mononucleotide cofactor in α-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate-oxidation level
SY Lyu, KH Lin, HW Yeh, YS Li, CM Huang, YL Wang, HW Shih, NS Hsu, ...
Acta Crystallographica Section D: Structural Biology 75 (10), 918-929, 2019
32019
Red-shifted luciferase-luciferin pairs for enhanced bioluminescence
H Ai, HW Yeh
US Patent 10,202,584, 2019
12019
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