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Sarah Gaffen
Sarah Gaffen
University of Pittsburgh
Verifisert e-postadresse på pitt.edu - Startside
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Structure and signalling in the IL-17 receptor family
SL Gaffen
Nature Reviews Immunology 9 (8), 556-567, 2009
18412009
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
SA Khader, GK Bell, JE Pearl, JJ Fountain, J Rangel-Moreno, GE Cilley, ...
Nature immunology 8 (4), 369-377, 2007
17652007
The IL-23–IL-17 immune axis: from mechanisms to therapeutic testing
SL Gaffen, R Jain, AV Garg, DJ Cua
Nature reviews immunology 14 (9), 585-600, 2014
16392014
Interleukin‐17 and its target genes: mechanisms of interleukin‐17 function in disease
RM Onishi, SL Gaffen
Immunology 129 (3), 311-321, 2010
12232010
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis
HR Conti, F Shen, N Nayyar, E Stocum, JN Sun, MJ Lindemann, AW Ho, ...
Journal of Experimental Medicine 206 (2), 299-311, 2009
12052009
The IL-17 family of cytokines in health and disease
MJ McGeachy, DJ Cua, SL Gaffen
Immunity 50 (4), 892-906, 2019
12012019
IL-17 signaling: the yin and the yang
N Amatya, AV Garg, SL Gaffen
Trends in immunology 38 (5), 310-322, 2017
7532017
Overview of interleukin-2 function, production and clinical applications
SL Gaffen, KD Liu
Cytokine 28 (3), 109-123, 2004
6652004
1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A
S Joshi, LC Pantalena, XK Liu, SL Gaffen, H Liu, C Rohowsky-Kochan, ...
Molecular and cellular biology 31 (17), 3653-3669, 2011
6062011
Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa
SA Khader, SL Gaffen, JK Kolls
Mucosal immunology 2 (5), 403-411, 2009
5822009
An overview of IL-17 function and signaling
SL Gaffen
Cytokine 43 (3), 402-407, 2008
5142008
An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor–dependent signals
JJ Yu, MJ Ruddy, GC Wong, C Sfintescu, PJ Baker, JB Smith, RT Evans, ...
Blood 109 (9), 3794-3802, 2007
4752007
Functional cooperation between interleukin-17 and tumor necrosis factor-α is mediated by CCAAT/enhancer-binding protein family members
MJ Ruddy, GC Wong, XK Liu, H Yamamoto, S Kasayama, KL Kirkwood, ...
Journal of Biological Chemistry 279 (4), 2559-2567, 2004
4722004
A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17
SL Gaffen, G Hajishengallis
Journal of dental research 87 (9), 817-828, 2008
4662008
IL-17 receptor–based signaling and implications for disease
X Li, R Bechara, J Zhao, MJ McGeachy, SL Gaffen
Nature immunology 20 (12), 1594-1602, 2019
4232019
Th17 cells in immunity to Candida albicans
N Hernández-Santos, SL Gaffen
Cell host & microbe 11 (5), 425-435, 2012
4032012
Recent advances in the IL-17 cytokine family
SL Gaffen
Current opinion in immunology 23 (5), 613-619, 2011
3922011
Structure–function relationships in the IL-17 receptor: implications for signal transduction and therapy
F Shen, SL Gaffen
Cytokine 41 (2), 92-104, 2008
3872008
Identification of common transcriptional regulatory elements in interleukin-17 target genes
F Shen, Z Hu, J Goswami, SL Gaffen
Journal of Biological Chemistry 281 (34), 24138-24148, 2006
3732006
Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17-and TNF-α-induced genes in bone cells
F Shen, MJ Ruddy, P Plamondon, SL Gaffen
Journal of leukocyte biology 77 (3), 388-399, 2005
3642005
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Artikler 1–20