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David K. Chang
David K. Chang
Professor of Surgical Oncology, University of Glasgow
Verifisert e-postadresse på glasgow.ac.uk - Startside
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Genomic analyses identify molecular subtypes of pancreatic cancer
P Bailey, DK Chang, K Nones, AL Johns, AM Patch, MC Gingras, ...
Nature 531 (7592), 47-52, 2016
35242016
Whole genomes redefine the mutational landscape of pancreatic cancer
N Waddell, M Pajic, AM Patch, DK Chang, KS Kassahn, P Bailey, ...
Nature 518 (7540), 495-501, 2015
28092015
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
2567*2020
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
22952012
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
VP Balachandran, M Łuksza, JN Zhao, V Makarov, JA Moral, R Remark, ...
Nature 551 (7681), 512-516, 2017
11002017
Whole-genome landscape of pancreatic neuroendocrine tumours
A Scarpa, DK Chang, K Nones, V Corbo, AM Patch, P Bailey, RT Lawlor, ...
Nature 543 (7643), 65-71, 2017
9352017
Molecular subtypes of pancreatic cancer
EA Collisson, P Bailey, DK Chang, AV Biankin
Nature reviews Gastroenterology & hepatology 16 (4), 207-220, 2019
8642019
CXCR2 inhibition profoundly suppresses metastases and augments immunotherapy in pancreatic ductal adenocarcinoma
CW Steele, SA Karim, JDG Leach, P Bailey, R Upstill-Goddard, L Rishi, ...
Cancer cell 29 (6), 832-845, 2016
8412016
Interrogating open issues in cancer precision medicine with patient-derived xenografts
AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ...
Nature Reviews Cancer 17 (4), 254-268, 2017
7282017
Integrated genomic characterization of pancreatic ductal adenocarcinoma
BJ Raphael, RH Hruban, AJ Aguirre, RA Moffitt, JJ Yeh, C Stewart, ...
Cancer cell 32 (2), 185-203. e13, 2017
6862017
Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide.
AL Goldstein, TL Low, M McAdoo, J McClure, GB Thurman, J Rossio, ...
Proceedings of the National Academy of Sciences 74 (2), 725-729, 1977
5561977
ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer
RE Miller, A Leary, CL Scott, V Serra, CJ Lord, D Bowtell, DK Chang, ...
Annals of Oncology 31 (12), 1606-1622, 2020
4002020
Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer
CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ...
Cell metabolism 29 (6), 1390-1399. e6, 2019
3922019
Margin clearance and outcome in resected pancreatic cancer
DK Chang, AL Johns, ND Merrett, AJ Gill, EK Colvin, CJ Scarlett, ...
Journal of Clinical Oncology 27 (17), 2855-2862, 2009
3902009
The prognostic and predictive value of serum CA19. 9 in pancreatic cancer
JL Humphris, DK Chang, AL Johns, CJ Scarlett, M Pajic, MD Jones, ...
Annals of oncology 23 (7), 1713-1722, 2012
3652012
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma
PA Pérez-Mancera, AG Rust, L Van Der Weyden, G Kristiansen, A Li, ...
Nature 486 (7402), 266-270, 2012
3572012
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy
BW Miller, JP Morton, M Pinese, G Saturno, NB Jamieson, E McGhee, ...
EMBO molecular medicine 7 (8), 1063-1076, 2015
2922015
Genome‐wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT‐ROBO, ITGA2 and MET signaling
K Nones, N Waddell, S Song, AM Patch, D Miller, A Johns, J Wu, ...
International journal of cancer 135 (5), 1110-1118, 2014
2632014
Precision medicine for advanced pancreas cancer: the individualized molecular pancreatic cancer therapy (IMPaCT) trial
LA Chantrill, AM Nagrial, C Watson, AL Johns, M Martyn-Smith, ...
Clinical cancer research 21 (9), 2029-2037, 2015
2462015
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ...
Nature communications 10 (1), 3637, 2019
2422019
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Artikler 1–20