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Anushka Goonawardena
Anushka Goonawardena
Roche pharmaceuticals
Verifisert e-postadresse på gene.com
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A cortical neural prosthesis for restoring and enhancing memory
TW Berger, RE Hampson, D Song, A Goonawardena, VZ Marmarelis, ...
Journal of neural engineering 8 (4), 046017, 2011
3562011
From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease
AJH Brown, SJ Bradley, FH Marshall, GA Brown, KA Bennett, J Brown, ...
Cell 184 (24), 5886-5901. e22, 2021
722021
Short-term memory is modulated by the spontaneous release of endocannabinoids: evidence from hippocampal population codes
SA Deadwyler, AV Goonawardena, RE Hampson
Behavioural pharmacology 18 (5-6), 571-580, 2007
712007
The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats
L Robinson, AV Goonawardena, RG Pertwee, RE Hampson, G Riedel
British journal of pharmacology 151 (5), 688-700, 2007
702007
Cannabinoid and cholinergic systems interact during performance of a short-term memory task in the rat
AV Goonawardena, L Robinson, RE Hampson, G Riedel
Learning & Memory 17 (10), 502-511, 2010
652010
WIN55, 212-2 induced deficits in spatial learning are mediated by cholinergic hypofunction
L Robinson, AV Goonawardena, R Pertwee, RE Hampson, B Platt, ...
Behavioural Brain Research 208 (2), 584-592, 2010
592010
Cannabinoids alter spontaneous firing, bursting, and cell synchrony of hippocampal principal cells
AV Goonawardena, G Riedel, RE Hampson
Hippocampus 21 (5), 520-531, 2011
412011
Closing the loop for memory prosthesis: detecting the role of hippocampal neural ensembles using nonlinear models
RE Hampson, D Song, RHM Chan, AJ Sweatt, MR Riley, ...
IEEE Transactions on Neural Systems and Rehabilitation Engineering 20 (4 …, 2012
372012
Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus
AV Goonawardena, J Sesay, CA Sexton, G Riedel, RE Hampson
Neuropharmacology 61 (5-6), 1016-1025, 2011
362011
Modulation of food consumption and sleep–wake cycle in mice by the neutral CB1 antagonist ABD459
AV Goonawardena, A Plano, L Robinson, R Ross, I Greig, RG Pertwee, ...
Behavioural pharmacology 26 (3), 289-303, 2015
252015
Recruitment of hippocampal neurons to encode behavioral events in the rat: Alterations in cognitive demand and cannabinoid exposure
AV Goonawardena, L Robinson, G Riedel, RE Hampson
Hippocampus 20 (9), 1083-1094, 2010
252010
A pilot study into the effects of the cb1 cannabinoid receptor agonist WIN55, 212‐2 or the antagonist/inverse agonist AM251 on sleep in rats
AV Goonawardena, A Plano, L Robinson, B Platt, RE Hampson, G Riedel
Sleep disorders 2011 (1), 178469, 2011
242011
Memory encoding in hippocampal ensembles is negatively influenced by cannabinoid CB1 receptors
RE Hampson, AJ Sweatt, AV Goonawardena, D Song, RHM Chan, ...
Behavioural pharmacology 22 (4), 335-346, 2011
232011
Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques
AV Goonawardena, SR Morairty, R Dell, GA Orellana, MC Hoener, ...
Neuropsychopharmacology 44 (8), 1485-1493, 2019
212019
Tracking the changes of hippocampal population nonlinear dynamics in rats learning a memory-dependent task
RHM Chan, D Song, AV Goonawardena, S Bough, J Sesay, RE Hampson, ...
2011 Annual International Conference of the IEEE Engineering in Medicine and …, 2011
142011
Alterations in high-frequency neuronal oscillations in a cynomolgus macaque test of sustained attention following NMDA receptor antagonism
AV Goonawardena, J Heiss, C Glavis-Bloom, G Trube, E Borroni, ...
Neuropsychopharmacology 41 (5), 1319-1328, 2016
112016
Systemic Blockade of the CB1 Receptor Augments Hippocampal Gene Expression Involved in Synaptic Plasticity but Perturbs Hippocampus-Dependent Learning …
KKA Horton, AV Goonawardena, J Sesay, AC Howlett, RE Hampson
Cannabis and cannabinoid research 4 (1), 33-41, 2019
102019
Changes of hippocampal CA3-CA1 population nonlinear dynamics across different training sessions in rats performing a memory-dependent task
RHM Chan, D Song, AV Goonawardena, S Bough, J Sesay, RE Hampson, ...
2010 Annual International Conference of the IEEE Engineering in Medicine and …, 2010
102010
Electrophysiological characterization of sleep/wake, activity and the response to caffeine in adult cynomolgus macaques
AV Goonawardena, SR Morairty, GA Orellana, AR Willoughby, ...
Neurobiology of Sleep and Circadian Rhythms 6, 9-23, 2019
82019
Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques (vol 44, pg 1485, 2019)
AV Goonawardena, SR Morairty, R Dell, GA Orellana, MC Hoener, ...
NEUROPSYCHOPHARMACOLOGY 48 (9), 1418-1418, 2023
2023
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