Dmitry Veprintsev

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Alan FershtEmeritus Group Leader, MRC Laboratory of Molecular Biology, University of CambridgeVerifisert e-postadresse på cam.ac.uk
Franziska Marie HeydenreichPhilipps-Universität MarburgVerifisert e-postadresse på pharmazie.uni-marburg.de
Prof. Assaf FriedlerInstitute of Chemistry, The Hebrew University of JerusalemVerifisert e-postadresse på mail.huji.ac.il
Michel BouvierProfessor of Biochem. and Mol. Med., IRIC, Univ. de MontréalVerifisert e-postadresse på umontreal.ca
Gebhard F. X SchertlerHead of Biology and Chemistry Devision, PSI / ETHVerifisert e-postadresse på psi.ch
Tilman FlockPalantir Technologies | Former Fellow at University of CambridgeVerifisert e-postadresse på palantir.com
Dr David Andrew SykesUniversity of NottinghamVerifisert e-postadresse på nottingham.ac.uk
Andreas C. JoergerStructural Genomics Consortium (SGC), Institute of Pharmaceutical Chemistry, Goethe UniversityVerifisert e-postadresse på pharmchem.uni-frankfurt.de
Roger L WilliamsGroup leader, Medical Research Council, Laboratory of Molecular BiologyVerifisert e-postadresse på mrc-lmb.cam.ac.uk
Stefan G.D. RüdigerBijvoet Center, Utrecht UniversityVerifisert e-postadresse på uu.nl
Tamara MiljusPostdoctoral Research Fellow, University of Birmingham, Department of Metabolism and Systems ScienceVerifisert e-postadresse på Bham.ac.uk
M. Madan BabuMember and Endowed Chair, St Jude Children's Research Hospital, USAVerifisert e-postadresse på stjude.org
Xavier DeupiSenior Scientist, Paul Scherrer InstituteVerifisert e-postadresse på psi.ch
Eugene PermyakovInstitute for Biological Instrumentation of the Russian Academy of Sciences, chief scientistVerifisert e-postadresse på ibp-ran.ru
Scott D EmrCornell UniversityVerifisert e-postadresse på cornell.edu
Dalibor MilićUniversity of Vienna, Max Perutz Labs ViennaVerifisert e-postadresse på univie.ac.at
Uwe GretherF. Hoffmann-La Roche LtdVerifisert e-postadresse på roche.com
Christopher G TateProgramme Leader, MRC Laboratory of Molecular Biology, CambridgeVerifisert e-postadresse på mrc-lmb.cam.ac.uk
Joerg StandfussPaul Scherrer InstituteVerifisert e-postadresse på psi.ch
Carol V RobinsonProfessor of Chemistry University of OxfordVerifisert e-postadresse på chem.ox.ac.uk

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Dmitry Veprintsev

Professor of Molecular and Cellular Pharmacology, University of Nottingham

Verifisert e-postadresse på nottingham.ac.uk - Startside

G protein coupled receptors GPCRs membrane proteins conformational dynamics pharmacology


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Targeted rescue of a destabilized mutant of p53 by an in silico screened drug FM Boeckler, AC Joerger, G Jaggi, TJ Rutherford, DB Veprintsev, ... Proceedings of the National Academy of Sciences 105 (30), 10360-10365, 2008	457	2008
Universal allosteric mechanism for Gα activation by GPCRs T Flock, CNJ Ravarani, D Sun, AJ Venkatakrishnan, M Kayikci, CG Tate, ... Nature 524 (7564), 173-179, 2015	403	2015
Structures of SAS-6 suggest its organization in centrioles M van Breugel, M Hirono, A Andreeva, H Yanagisawa, S Yamaguchi, ... Science 331 (6021), 1196-1199, 2011	376	2011
Hsp90-Tau complex reveals molecular basis for specificity in chaperone action GE Karagöz, AMS Duarte, E Akoury, H Ippel, J Biernat, TM Luengo, ... Cell 156 (5), 963-974, 2014	356	2014
Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region AJ Venkatakrishnan, X Deupi, G Lebon, FM Heydenreich, T Flock, ... Nature 536 (7617), 484-487, 2016	347	2016
A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants A Friedler, LO Hansson, DB Veprintsev, SMV Freund, TM Rippin, ... Proceedings of the National Academy of Sciences 99 (2), 937-942, 2002	346	2002
Cooperative binding of tetrameric p53 to DNA RL Weinberg, DB Veprintsev, AR Fersht Journal of molecular biology 341 (5), 1145-1159, 2004	322	2004
ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes H Teo, DJ Gill, J Sun, O Perisic, DB Veprintsev, Y Vallis, SD Emr, ... Cell 125 (1), 99-111, 2006	320	2006
Comparative binding of p53 to its promoter and DNA recognition elements RL Weinberg, DB Veprintsev, M Bycroft, AR Fersht Journal of molecular biology 348 (3), 589-596, 2005	253	2005
Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium Z Hayouka, J Rosenbluh, A Levin, S Loya, M Lebendiker, D Veprintsev, ... Proceedings of the National Academy of Sciences 104 (20), 8316-8321, 2007	237	2007
Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor MR Fernandez-Fernandez, DB Veprintsev, AR Fersht Proceedings of the National Academy of Sciences 102 (13), 4735-4740, 2005	234	2005
The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger S Eustermann, H Videler, JC Yang, PT Cole, D Gruszka, D Veprintsev, ... Journal of molecular biology 407 (1), 149-170, 2011	223	2011
GPCR activation mechanisms across classes and macro/microscales AS Hauser, AJ Kooistra, C Munk, FM Heydenreich, DB Veprintsev, ... Nature structural & molecular biology 28 (11), 879-888, 2021	206	2021
Backbone NMR reveals allosteric signal transduction networks in the β₁-adrenergic receptor S Isogai, X Deupi, C Opitz, FM Heydenreich, CJ Tsai, F Brueckner, ... Nature 530 (7589), 237-241, 2016	205	2016
Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations AC Joerger, HC Ang, DB Veprintsev, CM Blair, AR Fersht Journal of Biological Chemistry 280 (16), 16030-16037, 2005	205	2005
Structural insight into the ESCRT‐I/‐II link and its role in MVB trafficking DJ Gill, H Teo, J Sun, O Perisic, DB Veprintsev, SD Emr, RL Williams The EMBO journal 26 (2), 600-612, 2007	185	2007
Structural evolution of p53, p63, and p73: implication for heterotetramer formation AC Joerger, S Rajagopalan, E Natan, DB Veprintsev, CV Robinson, ... Proceedings of the National Academy of Sciences 106 (42), 17705-17710, 2009	174	2009
Kinetic instability of p53 core domain mutants: implications for rescue by small molecules A Friedler, DB Veprintsev, LO Hansson, AR Fersht Journal of Biological Chemistry 278 (26), 24108-24112, 2003	173	2003
The central region of HDM2 provides a second binding site for p53 GW Yu, S Rudiger, D Veprintsev, S Freund, MR Fernandez-Fernandez, ... Proceedings of the National Academy of Sciences 103 (5), 1227-1232, 2006	169	2006
Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24 S Ghazi-Tabatabai, S Saksena, JM Short, AV Pobbati, DB Veprintsev, ... Structure 16 (9), 1345-1356, 2008	167	2008

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