Simon Dujardin, PhD

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Bradley HymanMassachusetts General Hospital, Harvard Medical SchoolVerifisert e-postadresse på partners.org
Luc BueeUniversité de LilleVerifisert e-postadresse på univ-lille.fr
Tarun KamathMD-PhD Student at Harvard Medical SchoolVerifisert e-postadresse på hms.harvard.edu
Rachel BennettAssistant Professor of Neurology, Massachusetts General Hospital, Harvard Medical SchoolVerifisert e-postadresse på mgh.harvard.edu
Matthew P. FroschMassachusetts General Hospital & Harvard Medical SchoolVerifisert e-postadresse på mgh.harvard.edu
Naomi KlicksteinGraduate Student, Columbia UniversityVerifisert e-postadresse på columbia.edu
George CarlsonUniversity of California, San Francisco; McLaughlin Research InstituteVerifisert e-postadresse på ucsf.edu
Susanne WegmannGroup Leader at DZNE BerlinVerifisert e-postadresse på berlin.de
Nicole DéglonLausanne University Hospital (CHUV)Verifisert e-postadresse på chuv.ch
Joris WinderickxKU LeuvenVerifisert e-postadresse på bio.kuleuven.be
Pieter BeerepootFog PharmaVerifisert e-postadresse på fogpharma.com
Judith A. Jebanathirajah SteenAssociate Professor of Neurology, Harvard Medical SchoolVerifisert e-postadresse på childrens.harvard.edu
Mukesh KumarPrincipal Scientist, Cell Signaling TechnologyVerifisert e-postadresse på cellsignal.com
J. Paul TaylorSt. Jude Children's Research HospitalVerifisert e-postadresse på stjude.org
Amayra Hernández-VegaInstitute for Bioengineering of Catalonia (IBEC)Verifisert e-postadresse på ibecbarcelona.eu
Bahareh EftekharzadehNereidTxVerifisert e-postadresse på Nereidtx.com
AA HymanMax Planck institute of molecular cell biology and geneticsVerifisert e-postadresse på mpi-cbg.de
Daniel J MullerETH Zurich, Department of Biosystems Science and EngineeringVerifisert e-postadresse på bsse.ethz.ch
Sarah DeVosDrug Maker in Residence, Curie.BioVerifisert e-postadresse på dmir.curie.bio
Bianca T CorjucPhD Candidate at Columbia UniversityVerifisert e-postadresse på cumc.columbia.edu

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Simon Dujardin, PhD

Instructor in Neurology, Massachusetts General Hospital, Harvard Medical School

Verifisert e-postadresse på mgh.harvard.edu - Startside

Tauopathies Alzheimer's disease neurosciences


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Tau protein liquid–liquid phase separation can initiate tau aggregation S Wegmann, B Eftekharzadeh, K Tepper, KM Zoltowska, RE Bennett, ... The EMBO journal 37 (7), e98049, 2018	966	2018
Tau PTM profiles identify patient heterogeneity and stages of Alzheimer’s disease H Wesseling, W Mair, M Kumar, CN Schlaffner, S Tang, P Beerepoot, ... Cell 183 (6), 1699-1713. e13, 2020	543	2020
Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ... Neuron 99 (5), 925-940. e7, 2018	422	2018
Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo MA Busche, S Wegmann, S Dujardin, C Commins, J Schiantarelli, ... Nature neuroscience 22 (1), 57-64, 2019	412	2019
What is the evidence that tau pathology spreads through prion-like propagation? A Mudher, M Colin, S Dujardin, M Medina, I Dewachter, SM Alavi Naini, ... Acta neuropathologica communications 5, 1-20, 2017	387	2017
Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease S Dujardin, C Commins, A Lathuiliere, P Beerepoot, AR Fernandes, ... Nature medicine 26 (8), 1256-1263, 2020	377	2020
Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies M Tardivel, S Bégard, L Bousset, S Dujardin, A Coens, R Melki, L Buée, ... Acta neuropathologica communications 4, 1-14, 2016	322	2016
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies S Dujardin, K Lécolle, R Caillierez, S Bégard, N Zommer, C Lachaud, ... Acta neuropathologica communications 2, 1-14, 2014	280	2014
Ectosomes: a new mechanism for non-exosomal secretion of tau protein S Dujardin, S Bégard, R Caillierez, C Lachaud, L Delattre, S Carrier, ... PloS one 9 (6), e100760, 2014	264	2014
Enhanced tau aggregation in the presence of amyloid β RE Bennett, SL DeVos, S Dujardin, B Corjuc, R Gor, J Gonzalez, AD Roe, ... The American journal of pathology 187 (7), 1601-1612, 2017	261	2017
CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia H Makishima, AM Jankowska, MA McDevitt, C O'Keefe, S Dujardin, ... Blood, The Journal of the American Society of Hematology 117 (21), e198-e206, 2011	193	2011
From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy M Colin, S Dujardin, S Schraen-Maschke, G Meno-Tetang, C Duyckaerts, ... Acta neuropathologica 139 (1), 3-25, 2020	173	2020
Selection of an efficient AAV vector for robust CNS transgene expression KS Hanlon, JC Meltzer, T Buzhdygan, MJ Cheng, M Sena-Esteves, ... Molecular Therapy Methods & Clinical Development 15, 320-332, 2019	149	2019
Different tau species lead to heterogeneous tau pathology propagation and misfolding S Dujardin, S Bégard, R Caillierez, C Lachaud, S Carrier, S Lieger, ... Acta neuropathologica communications 6, 1-12, 2018	112	2018
Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo SL DeVos, BT Corjuc, C Commins, S Dujardin, RN Bannon, D Corjuc, ... Brain 141 (7), 2194-2212, 2018	111	2018
Invited review: Animal models of tauopathies and their implications for research/translation into the clinic S Dujardin, M Colin, L Buée Neuropathology and applied neurobiology 41 (1), 59-80, 2015	100	2015
Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism JM Cooper, A Lathuiliere, M Migliorini, AL Arai, MM Wani, S Dujardin, ... Journal of Biological Chemistry 296, 2021	98	2021
Tau prion-like propagation: state of the art and current challenges S Dujardin, BT Hyman Tau Biology, 305-325, 2020	80	2020
In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy M Calvo-Rodriguez, SS Hou, AC Snyder, S Dujardin, H Shirani, ... Acta neuropathologica communications 7, 1-10, 2019	55	2019
A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease D Sepulveda-Falla, L Chavez-Gutierrez, E Portelius, JI Vélez, S Dujardin, ... Acta neuropathologica 141, 217-233, 2021	53	2021

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