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Michael Birrer
Michael Birrer
Professor Medicine HMS
Verifisert e-postadresse på partners.org
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Integrated genomic analyses of ovarian carcinoma
Cancer Genome Atlas Research Network
Nature 474 (7353), 609, 2011
57312011
Integrated genomic characterization of endometrial carcinoma
DA Levine, ...
Nature 497 (7447), 67-73, 2013
53242013
The immune landscape of cancer
V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ...
Immunity 48 (4), 812-830. e14, 2018
50252018
An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ...
Cell 173 (2), 400-416. e11, 2018
30772018
Incorporation of bevacizumab in the primary treatment of ovarian cancer
RA Burger, MF Brady, MA Bookman, GF Fleming, BJ Monk, H Huang, ...
New England Journal of Medicine 365 (26), 2473-2483, 2011
29662011
Oncogenic signaling pathways in the cancer genome atlas
F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ...
Cell 173 (2), 321-337. e10, 2018
28362018
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
24302018
Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer
KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ...
Cell 173 (2), 291-304. e6, 2018
22782018
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
M Verheij, R Bose, X Hua Lin, B Yao, WD Jarvis, S Grant, MJ Birrer, ...
Nature 380 (6569), 75-79, 1996
22401996
Machine learning identifies stemness features associated with oncogenic dedifferentiation
TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ...
Cell 173 (2), 338-354. e15, 2018
18552018
Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial
RL Coleman, AM Oza, D Lorusso, C Aghajanian, A Oaknin, A Dean, ...
The Lancet 390 (10106), 1949-1961, 2017
17722017
p53: a frequent target for genetic abnormalities in lung cancer
T Takahashi, MM Nau, I Chiba, MJ Birrer, RK Rosenberg, M Vinocour, ...
Science 246 (4929), 491-494, 1989
16101989
BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation–Positive Women With Ovarian Cancer: A Report From the Australian Ovarian …
K Alsop, S Fereday, C Meldrum, A DeFazio, C Emmanuel, J George, ...
Journal of clinical oncology 30 (21), 2654-2663, 2012
14812012
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
DD Bowtell, S Böhm, AA Ahmed, PJ Aspuria, RC Bast Jr, V Beral, ...
Nature reviews Cancer 15 (11), 668-679, 2015
12852015
Integrated genomic and molecular characterization of cervical cancer
Cancer Genome Atlas Research Network
Nature 543 (7645), 378, 2017
1200*2017
Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas
TA Knijnenburg, L Wang, MT Zimmermann, N Chambwe, GF Gao, ...
Cell reports 23 (1), 239-254. e6, 2018
10162018
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
T Smeal, B Binetruy, DA Mercola, M Birrer, M Karin
Nature 354 (6353), 494-496, 1991
10121991
Genomic and functional approaches to understanding cancer aneuploidy
AM Taylor, J Shih, G Ha, GF Gao, X Zhang, AC Berger, SE Schumacher, ...
Cancer cell 33 (4), 676-689. e3, 2018
9852018
Spatial organization and molecular correlation of tumor-infiltrating lymphocytes using deep learning on pathology images
J Saltz, R Gupta, L Hou, T Kurc, P Singh, V Nguyen, D Samaras, ...
Cell reports 23 (1), 181-193. e7, 2018
9512018
Comprehensive and integrated genomic characterization of adult soft tissue sarcomas
AJ Lazar, MD McLellan, MH Bailey, CA Miller, EL Appelbaum, MG Cordes, ...
Cell 171 (4), 950-965, 2017
9302017
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Artikler 1–20