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Ville Mustonen
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The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ...
Nature 578 (7793), 94-101, 2020
30862020
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
2561*2020
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ...
Nature 534 (7605), 47-54, 2016
23672016
Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts
E Papaemmanuil, M Cazzola, J Boultwood, L Malcovati, P Vyas, D Bowen, ...
New England Journal of Medicine 365 (15), 1384-1395, 2011
14922011
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ...
Nature 469 (7331), 539-542, 2011
14542011
The evolutionary history of 2,658 cancers
M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ...
Nature 578 (7793), 122-128, 2020
10132020
Pathway and network analysis of cancer genomes
Nature methods 12 (7), 615-621, 2015
3862015
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ...
Cell 184 (8), 2239-2254. e39, 2021
3832021
Predicting evolution
M Lässig, V Mustonen, AM Walczak
Nature ecology & evolution 1 (3), 0077, 2017
3232017
A high-definition view of functional genetic variation from natural yeast genomes
A Bergström, JT Simpson, F Salinas, B Barré, L Parts, A Zia, ...
Molecular biology and evolution 31 (4), 872-888, 2014
3182014
From fitness landscapes to seascapes: non-equilibrium dynamics of selection and adaptation
V Mustonen, M Lässig
Trends in Genetics 25 (3), 111-119, 2009
2852009
Fitness flux and ubiquity of adaptive evolution
V Mustonen, M Lässig
Proceedings of the National Academy of Sciences 107 (9), 4248, 2010
2102010
Prediction of antibiotic resistance in Escherichia coli from large-scale pan-genome data
D Moradigaravand, M Palm, A Farewell, V Mustonen, J Warringer, L Parts
PLoS computational biology 14 (12), e1006258, 2018
2082018
High-definition reconstruction of clonal composition in cancer
A Fischer, I Vázquez-García, CJR Illingworth, V Mustonen
Cell reports 7 (5), 1740-1752, 2014
1952014
Computational approaches to identify functional genetic variants in cancer genomes
Nature methods 10 (8), 723-729, 2013
1892013
Evolutionary population genetics of promoters: Predicting binding sites and functional phylogenies
V Mustonen, M Lässig
Proceedings of the National Academy of Sciences of the United States of …, 2005
1512005
Energy-dependent fitness: A quantitative model for the evolution of yeast transcription factor binding sites
V Mustonen, J Kinney, CG Callan, M Lässig
Proceedings of the National Academy of Sciences 105 (34), 12376, 2008
1422008
High-resolution mapping of complex traits with a four-parent advanced intercross yeast population
FA Cubillos, L Parts, F Salinas, A Bergström, E Scovacricchi, A Zia, ...
Genetics 195 (3), 1141-1155, 2013
1392013
EMu: probabilistic inference of mutational processes and their localization in the cancer genome
A Fischer, CJR Illingworth, PJ Campbell, V Mustonen
Genome biology 14, 1-10, 2013
1352013
Emergent Neutrality in Adaptive Asexual Evolution
S Schiffels, G Szöllösi, V Mustonen, M Lässig
Genetics, 2011
1302011
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Artikler 1–20