Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity JP Hewitson, JR Grainger, RM Maizels Molecular and biochemical parasitology 167 (1), 1-11, 2009 | 894 | 2009 |
Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway JR Grainger, KA Smith, JP Hewitson, HJ McSorley, Y Harcus, KJ Filbey, ... Journal of Experimental Medicine 207 (11), 2331-2341, 2010 | 578 | 2010 |
IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1 SJ Jenkins, D Ruckerl, GD Thomas, JP Hewitson, S Duncan, ... Journal of Experimental Medicine 210 (11), 2477-2491, 2013 | 477 | 2013 |
Immunomodulation by helminth parasites: defining mechanisms and mediators HJ McSorley, JP Hewitson, RM Maizels International journal for parasitology 43 (3-4), 301-310, 2013 | 387 | 2013 |
The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory–secretory products JP Hewitson, YM Harcus, RS Curwen, AA Dowle, AK Atmadja, PD Ashton, ... Molecular and biochemical parasitology 160 (1), 8-21, 2008 | 285 | 2008 |
Commensal-pathogen interactions in the intestinal tract: lactobacilli promote infection with, and are promoted by, helminth parasites LA Reynolds, KA Smith, KJ Filbey, Y Harcus, JP Hewitson, SA Redpath, ... Gut microbes 5 (4), 522-532, 2014 | 280 | 2014 |
Susceptibility and immunity to helminth parasites RM Maizels, JP Hewitson, KA Smith Current opinion in immunology 24 (4), 459-466, 2012 | 274 | 2012 |
A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells CJC Johnston, DJ Smyth, RB Kodali, MPJ White, Y Harcus, KJ Filbey, ... Nature communications 8 (1), 1741, 2017 | 214 | 2017 |
HpARI protein secreted by a helminth parasite suppresses interleukin-33 M Osbourn, DC Soares, F Vacca, ES Cohen, IC Scott, WF Gregory, ... Immunity 47 (4), 739-751. e5, 2017 | 189 | 2017 |
Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of venom allergen-like (VAL) proteins JP Hewitson, Y Harcus, J Murray, M van Agtmaal, KJ Filbey, JR Grainger, ... Journal of proteomics 74 (9), 1573-1594, 2011 | 185 | 2011 |
Modulation of the host's immune response by schistosome larvae SJ Jenkins, JP Hewitson, GR Jenkins, AP Mountford Parasite immunology 27 (10‐11), 385-393, 2005 | 177 | 2005 |
Immunity induced by the radiation‐attenuated schistosome vaccine JP Hewitson, PA Hamblin, AP Mountford Parasite immunology 27 (7‐8), 271-280, 2005 | 174 | 2005 |
Vaccination against helminth parasite infections JP Hewitson, RM Maizels Expert review of vaccines 13 (4), 473-487, 2014 | 165 | 2014 |
Immune modulation and modulators in Heligmosomoides polygyrus infection RM Maizels, JP Hewitson, J Murray, YM Harcus, B Dayer, KJ Filbey, ... Experimental parasitology 132 (1), 76-89, 2012 | 161 | 2012 |
Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection KJ Filbey, JR Grainger, KA Smith, L Boon, N Van Rooijen, Y Harcus, ... Immunology and cell biology 92 (5), 436-448, 2014 | 160 | 2014 |
Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and-independent pathways SJ Jenkins, JP Hewitson, S Ferret-Bernard, AP Mountford International immunology 17 (11), 1409-1418, 2005 | 101 | 2005 |
Low-level regulatory T-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths KA Smith, KJ Filbey, LA Reynolds, JP Hewitson, Y Harcus, L Boon, ... Mucosal immunology 9 (2), 428-443, 2016 | 89 | 2016 |
Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens … JP Hewitson, KJ Filbey, J Esser-von Bieren, M Camberis, C Schwartz, ... PLoS pathogens 11 (3), e1004676, 2015 | 88 | 2015 |
Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity JP Hewitson, AC Ivens, Y Harcus, KJ Filbey, HJ McSorley, J Murray, ... PLoS pathogens 9 (8), e1003492, 2013 | 71 | 2013 |
The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an ‘M2’phenotype in response to Th2 … KJ Mylonas, SJ Jenkins, RFP Castellan, D Ruckerl, K McGregor, ... Immunobiology 220 (7), 924-933, 2015 | 67 | 2015 |