The EuroPhysiome, STEP and a roadmap for the virtual physiological human JW Fenner, B Brook, G Clapworthy, PV Coveney, V Feipel, H Gregersen, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2008 | 146 | 2008 |
Numerical solutions for unsteady gravity-driven flows in collapsible tubes: evolution and roll-wave instability of a steady state BS Brook, S Falle, TJ Pedley Journal of Fluid Mechanics 396, 223-256, 1999 | 146 | 1999 |
Blood pressure and flow rate in the giraffe jugular vein TJ Pedley, BS Brook, RS Seymour, TJ Pedley, BS Brook, RS Seymour Philosophical Transactions of the Royal Society of London. Series B …, 1996 | 124 | 1996 |
Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling PB Noble, CD Pascoe, B Lan, S Ito, LEM Kistemaker, AL Tatler, T Pera, ... Pulmonary Pharmacology & Therapeutics, 2014 | 106 | 2014 |
DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment R Saunders, H Kaul, R Berair, S Gonem, A Singapuri, AJ Sutcliffe, ... Science translational medicine 11 (479), eaao6451, 2019 | 73 | 2019 |
A model for time-dependent flow in (giraffe jugular) veins: uniform tube properties BS Brook, TJ Pedley Journal of biomechanics 35 (1), 95-107, 2002 | 59 | 2002 |
Activation of Store-Operated Calcium Entry in Airway Smooth Muscle Cells: Insight from a Mathematical Model H Croisier, X Tan, JF Perez-Zoghbi, MJ Sanderson, J Sneyd, BS Brook PLOS ONE 8 (7), e69598, 2013 | 52 | 2013 |
A biomechanical model of agonist-initiated contraction in the asthmatic airway BS Brook, SE Peel, IP Hall, AZ Politi, J Sneyd, Y Bai, MJ Sanderson, ... Respiratory physiology & neurobiology 170 (1), 44-58, 2010 | 52 | 2010 |
In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss IL Chernyavsky, RJ Russell, RM Saunders, GE Morris, R Berair, ... European Respiratory Journal 51 (5), 1701680, 2018 | 51 | 2018 |
Mathematical modelling of cytokine-mediated inflammation in rheumatoid arthritis M Baker, S Denman-Johnson, BS Brook, I Gaywood, MR Owen Mathematical Medicine and Biology, 2012 | 44 | 2012 |
Small airway hyperresponsiveness in COPD: relationship between structure and function in lung slices H Maarsingh, CM Bidan, BS Brook, AB Zuidhof, CRS Elzinga, M Smit, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 316 (3 …, 2019 | 43 | 2019 |
Radiological imaging as the basis for a simulation software of ventilation in the tracheo-bronchial tree S Ley, D Mayer, B Brook, E van Beek, C Heussel, D Rinck, R Hose, ... European radiology 12 (9), 2218-2228, 2002 | 37 | 2002 |
A novel computational model predicts key regulators of chemokine gradient formation in lymph nodes and site-specific roles for CCL19 and ACKR4 M Jafarnejad, DC Zawieja, BS Brook, RJB Nibbs, JE Moore The Journal of Immunology 199 (7), 2291-2304, 2017 | 36 | 2017 |
Nonlinear compliance modulates dynamic bronchoconstriction in a multiscale airway model B Brook, JE Hiorns, OE Jensen Biophysical Society 107 (12), 2014 | 36 | 2014 |
Nonlinear Compliance Modulates Dynamic Bronchoconstriction in a Multiscale Airway Model JE Hiorns, OE Jensen, BS Brook Biophysical Journal 107 (12), 3021-3033, 2014 | 36 | 2014 |
A theoretical model of inflammation-and mechanotransduction-driven asthmatic airway remodelling MR Hill, CJ Philp, CK Billington, AL Tatler, SR Johnson, RD O’Dea, ... Biomechanics and modeling in mechanobiology 17 (5), 1451-1470, 2018 | 29 | 2018 |
Airway and parenchymal strains during bronchoconstriction in the precision cut lung slice JE Hiorns, CM Bidan, OE Jensen, R Gosens, JJ Fredberg, ... Frontiers in Physiology 7, 309, 2016 | 29 | 2016 |
Repeated airway constrictions in mice do not alter respiratory function S Mailhot-Larouche, L Deschênes, M Gazzola, K Lortie, C Henry, ... Journal of Applied Physiology 124 (6), 1483-1490, 2018 | 27 | 2018 |
Ryanodine receptor sensitization results in abnormal calcium signaling in airway smooth muscle cells B Brook, H Croisier, X Tan, J Chen, J Sneyd, MJ Sanderson American Thoracic Society 53 (5), 2015 | 26 | 2015 |
Ryanodine Receptor Sensitization Results in Abnormal Calcium Signaling in Airway Smooth Muscle Cells H Croisier, X Tan, J Chen, J Sneyd, MJ Sanderson, BS Brook American journal of respiratory cell and molecular biology 53 (5), 703-711, 2015 | 26 | 2015 |