Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro KH Benam, R Villenave, C Lucchesi, A Varone, C Hubeau, HH Lee, ... Nature methods 13 (2), 151-157, 2016 | 837 | 2016 |
Engineered in vitro disease models KH Benam, S Dauth, B Hassell, A Herland, A Jain, KJ Jang, K Karalis, ... Annual Review of Pathology: Mechanisms of Disease 10 (1), 195-262, 2015 | 654 | 2015 |
Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function OYF Henry, R Villenave, MJ Cronce, WD Leineweber, MA Benz, ... Lab on a Chip 17 (13), 2264-2271, 2017 | 431 | 2017 |
In vitro modeling of respiratory syncytial virus infection of pediatric bronchial epithelium, the primary target of infection in vivo R Villenave, S Thavagnanam, S Sarlang, J Parker, I Douglas, G Skibinski, ... Proceedings of the National Academy of Sciences 109 (13), 5040-5045, 2012 | 229 | 2012 |
Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro R Villenave, SQ Wales, T Hamkins-Indik, E Papafragkou, JC Weaver, ... PloS one 12 (2), e0169412, 2017 | 195 | 2017 |
Relative respiratory syncytial virus cytopathogenesis in upper and lower respiratory tract epithelium H Guo-Parke, P Canning, I Douglas, R Villenave, LG Heaney, PV Coyle, ... American journal of respiratory and critical care medicine 188 (7), 842-851, 2013 | 114 | 2013 |
A microengineered airway lung chip models key features of viral-induced exacerbation of asthma JC Nawroth, C Lucchesi, D Cheng, A Shukla, J Ngyuen, T Shroff, ... American journal of respiratory cell and molecular biology 63 (5), 591-600, 2020 | 108 | 2020 |
EGFR interacts with the fusion protein of respiratory syncytial virus strain 2-20 and mediates infection and mucin expression MG Currier, S Lee, CC Stobart, AL Hotard, R Villenave, J Meng, CD Pretto, ... PLoS pathogens 12 (5), e1005622, 2016 | 108 | 2016 |
Stem cell-based Lung-on-Chips: The best of both worlds? JC Nawroth, R Barrile, D Conegliano, S van Riet, PS Hiemstra, ... Advanced drug delivery reviews 140, 12-32, 2019 | 94 | 2019 |
Respiratory syncytial virus interaction with human airway epithelium R Villenave, MD Shields, UF Power Trends in microbiology 21 (5), 238-244, 2013 | 91 | 2013 |
Differential cytopathogenesis of respiratory syncytial virus prototypic and clinical isolates in primary pediatric bronchial epithelial cells R Villenave, D O'Donoghue, S Thavagnanam, O Touzelet, G Skibinski, ... Virology Journal 8, 1-9, 2011 | 85 | 2011 |
Low shear microfluidic devices and methods of use and manufacturing thereof DE Ingber, KH Benam, R Villenave, GA Hamilton, B Hassell, CD Hinojosa, ... US Patent 11,119,093, 2021 | 79 | 2021 |
A 3-D well-differentiated model of pediatric bronchial epithelium demonstrates unstimulated morphological differences between asthmatic and nonasthmatic cells J Parker, S Sarlang, S Thavagnanam, G Williamson, D O'donoghue, ... Pediatric research 67 (1), 17-22, 2010 | 77 | 2010 |
Induction and antagonism of antiviral responses in respiratory syncytial virus-infected pediatric airway epithelium R Villenave, L Broadbent, I Douglas, JD Lyons, PV Coyle, MN Teng, ... Journal of virology 89 (24), 12309-12318, 2015 | 70 | 2015 |
Organomimetic devices and methods of use and manufacturing thereof J Fernandez-alcon, N Wen, R Novak, DE Ingber, GA Hamilton, ... US Patent 12,173,263, 2024 | 66 | 2024 |
Cytopathogenesis of Sendai virus in well-differentiated primary pediatric bronchial epithelial cells R Villenave, O Touzelet, S Thavagnanam, S Sarlang, J Parker, ... Journal of virology 84 (22), 11718-11728, 2010 | 47 | 2010 |
Towards in vitro models for reducing or replacing the use of animals in drug testing DM Stresser, AK Kopec, P Hewitt, RN Hardwick, TR Van Vleet, ... Nature Biomedical Engineering 8 (8), 930-935, 2024 | 46 | 2024 |
Chlorogenic compounds from coffee beans exert activity against respiratory viruses V Sinisi, A Stevaert, F Berti, C Forzato, F Benedetti, L Navarini, A Camps, ... Planta Medica 83 (07), 615-623, 2017 | 44 | 2017 |
In vitro modeling of RSV infection and cytopathogenesis in well-differentiated human primary airway epithelial cells (WD-PAECs) L Broadbent, R Villenave, H Guo-Parke, I Douglas, MD Shields, UF Power Human Respiratory Syncytial Virus: Methods and Protocols, 119-139, 2016 | 33 | 2016 |
Contribution of host defence proteins and peptides to Host-Microbiota interactions in chronic inflammatory lung diseases AM Van der Does, GD Amatngalim, B Keijser, PS Hiemstra, R Villenave Vaccines 6 (3), 49, 2018 | 13 | 2018 |