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Elizabeth Jaffee
Elizabeth Jaffee
Johns Hopkins University School of Medicine
Verifisert e-postadresse på jhmi.edu - Startside
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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
47822008
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor …
G Dranoff, E Jaffee, A Lazenby, P Golumbek, H Levitsky, K Brose, ...
Proceedings of the National Academy of Sciences 90 (8), 3539-3543, 1993
34451993
Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
AYC Huang, P Golumbek, M Ahmadzadeh, E Jaffee, D Pardoll, H Levitsky
Science 264 (5161), 961-965, 1994
15441994
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ...
Science 324 (5924), 217-217, 2009
10522009
Mechanisms of immune evasion by tumors
CG Drake, E Jaffee, DM Pardoll
Advances in immunology 90, 51-81, 2006
9142006
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene …
P Argani, C Iacobuzio-Donahue, B Ryu, C Rosty, M Goggins, RE Wilentz, ...
Clinical cancer research 7 (12), 3862-3868, 2001
7282001
Novel allogeneic granulocyte-macrophage colony-stimulating factor–secreting tumor vaccine for pancreatic cancer: a phase I trial of safety and immune activation
EM Jaffee, RH Hruban, B Biedrzycki, D Laheru, K Schepers, PR Sauter, ...
Journal of Clinical Oncology 19 (1), 145-156, 2001
7012001
Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer
DT Le, A Wang-Gillam, V Picozzi, TF Greten, T Crocenzi, G Springett, ...
Journal of clinical oncology 33 (12), 1325-1333, 2015
6902015
Compromised HOXA5 function can limit p53 expression in human breast tumours
V Raman, SA Martensen, D Reisman, E Evron, WF Odenwald, E Jaffee, ...
Nature 405 (6789), 974-978, 2000
6452000
Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer
DT Le, E Lutz, JN Uram, EA Sugar, B Onners, S Solt, L Zheng, LA Diaz Jr, ...
Journal of immunotherapy 36 (7), 382-389, 2013
6272013
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
CA Iacobuzio-Donahue, A Maitra, M Olsen, AW Lowe, NT Van Heek, ...
The American journal of pathology 162 (4), 1151-1162, 2003
5812003
Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation
ER Lutz, AA Wu, E Bigelow, R Sharma, G Mo, K Soares, S Solt, A Dorman, ...
Cancer immunology research 2 (7), 616-631, 2014
5552014
Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2 …
JPH Machiels, RT Reilly, LA Emens, AM Ercolini, RY Lei, D Weintraub, ...
Cancer research 61 (9), 3689-3697, 2001
5532001
Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by ex Vivo Granulocyte-Macrophage Colony-stimulating Factor Gene Transfer
JW Simons, EM Jaffee, CE Weber, HI Levitsky, WG Nelson, MA Carducci, ...
Cancer research 57 (8), 1537-1546, 1997
5391997
Galectin-3 Shapes Antitumor Immune Responses by Suppressing CD8+ T Cells via LAG-3 and Inhibiting Expansion of Plasmacytoid Dendritic Cells
T Kouo, L Huang, AB Pucsek, M Cao, S Solt, T Armstrong, E Jaffee
Cancer immunology research 3 (4), 412-423, 2015
5342015
The determinants of tumour immunogenicity
T Blankenstein, PG Coulie, E Gilboa, EM Jaffee
Nature Reviews Cancer 12 (4), 307-313, 2012
5292012
The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product.
AY Huang, PH Gulden, AS Woods, MC Thomas, CD Tong, WEI Wang, ...
Proceedings of the National Academy of Sciences 93 (18), 9730-9735, 1996
5131996
Recruitment of latent pools of high-avidity CD8+ T cells to the antitumor immune response
AM Ercolini, BH Ladle, EA Manning, LW Pfannenstiel, TD Armstrong, ...
Journal of Experimental Medicine 201 (10), 1591-1602, 2005
4812005
PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors
KC Soares, AA Rucki, AA Wu, K Olino, Q Xiao, Y Chai, A Wamwea, ...
Journal of immunotherapy 38 (1), 1-11, 2015
4662015
A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma: a phase II trial of safety, efficacy …
L Eric, CJ Yeo, KD Lillemoe, B Biedrzycki, B Kobrin, J Herman, E Sugar, ...
Annals of surgery 253 (2), 328-335, 2011
4572011
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