Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues H Ishikawa, DA Colby, S Seto, P Va, A Tam, H Kakei, TJ Rayl, I Hwang, ... Journal of the American Chemical Society 131 (13), 4904-4916, 2009 | 403 | 2009 |
Direct Coupling of Catharanthine and Vindoline to Provide Vinblastine: Total Synthesis of (+)- and ent-(−)-Vinblastine H Ishikawa, DA Colby, DL Boger Journal of the American Chemical Society 130 (2), 420-421, 2008 | 218 | 2008 |
Cleavage of Carbon− Carbon Bonds through the Mild Release of Trifluoroacetate: Generation of α, α-Difluoroenolates for Aldol Reactions C Han, EH Kim, DA Colby Journal of the American Chemical Society 133 (15), 5802-5805, 2011 | 174 | 2011 |
Application of the pentafluorosulfanyl group as a bioisosteric replacement MF Sowaileh, RA Hazlitt, DA Colby ChemMedChem 12 (18), 1481-1490, 2017 | 140 | 2017 |
Recent applications of α-carbonyl sulfoxonium ylides in rhodium-and iridium-catalyzed C–H functionalizations X Wu, S Sun, JT Yu, J Cheng Synlett 30 (01), 21-29, 2019 | 118 | 2019 |
Evaluation of Difluoromethyl Ketones as Agonists of the γ-Aminobutyric Acid Type B (GABAB) Receptor C Han, AE Salyer, EH Kim, X Jiang, RE Jarrard, MS Powers, AM Kirchhoff, ... Journal of Medicinal Chemistry 56 (6), 2456-2465, 2013 | 109 | 2013 |
Amino-derivatives of the sesquiterpene lactone class of natural products as prodrugs JR Woods, H Mo, AA Bieberich, T Alavanja, DA Colby MedChemComm 4 (1), 27-33, 2013 | 109 | 2013 |
The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma EJ Gunn, JT Williams, DT Huynh, MJ Iannotti, C Han, FJ Barrios, ... Leukemia & lymphoma 52 (6), 1085-1097, 2011 | 103 | 2011 |
Fluorinated Amino-Derivatives of the Sesquiterpene Lactone, Parthenolide, as 19F NMR Probes in Deuterium-Free Environments JR Woods, H Mo, AA Bieberich, T Alavanja, DA Colby Journal of medicinal chemistry 54 (22), 7934-7941, 2011 | 87 | 2011 |
Synthesis of α-Halo-α, α-difluoromethyl Ketones by a Trifluoroacetate Release/Halogenation Protocol JP John, DA Colby The Journal of organic chemistry 76 (21), 9163-9168, 2011 | 81 | 2011 |
Semisynthetic derivatives of sesquiterpene lactones by palladium-catalyzed arylation of the α-methylene-γ-lactone substructure C Han, FJ Barrios, MV Riofski, DA Colby The Journal of Organic Chemistry 74 (18), 7176-7179, 2009 | 79 | 2009 |
Total synthesis and evaluation of cytostatin, its C10− C11 diastereomers, and additional key analogues: impact on PP2A inhibition BG Lawhorn, SB Boga, SE Wolkenberg, DA Colby, CM Gauss, ... Journal of the American Chemical Society 128 (51), 16720-16732, 2006 | 70 | 2006 |
On the successful use of inquiry-driven experiments in the organic chemistry laboratory CN Hammond, JR Mohrig, DA Colby Journal of Chemical Education 84 (6), 992, 2007 | 64 | 2007 |
Exploiting the facile release of trifluoroacetate for the α-methylenation of the sterically hindered carbonyl groups on (+)-sclareolide and (−)-eburnamonine MV Riofski, JP John, MM Zheng, J Kirshner, DA Colby The Journal of organic chemistry 76 (10), 3676-3683, 2011 | 62 | 2011 |
Activation of the γ-Aminobutyric Acid Type B (GABAB) Receptor by Agonists and Positive Allosteric Modulators: Miniperspective KM Brown, KK Roy, GH Hockerman, RJ Doerksen, DA Colby Journal of medicinal chemistry 58 (16), 6336-6347, 2015 | 55 | 2015 |
In vitro characterization of transport and metabolism of the alkaloids: vincamine, vinpocetine and eburnamonine TE Fandy, I Abdallah, M Khayat, DA Colby, HE Hassan Cancer chemotherapy and pharmacology 77, 259-267, 2016 | 50 | 2016 |
Synthesis of the C10–C17 fragment of aurisides and callipeltosides M Romero-Ortega, DA Colby, HF Olivo Tetrahedron letters 43 (36), 6439-6441, 2002 | 46 | 2002 |
Amidinate salt of hexafluoroacetone hydrate for the preparation of fluorinated compounds by the release of trifluoroacetate MV Riofski, AD Hart, DA Colby Organic Letters 15 (1), 208-211, 2013 | 43 | 2013 |
Proposed actions for the US Food and Drug Administration to implement to minimize adverse effects associated with energy drink consumption J Thorlton, DA Colby, P Devine American Journal of Public Health 104 (7), 1175-1180, 2014 | 38 | 2014 |
A practical deuterium-free NMR method for the rapid determination of 1-octanol/water partition coefficients of pharmaceutical agents H Mo, KM Balko, DA Colby Bioorganic & medicinal chemistry letters 20 (22), 6712-6715, 2010 | 36 | 2010 |