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IOANNA A. ROTA
IOANNA A. ROTA
Zweryfikowany adres z paediatrics.ox.ac.uk
Tytuł
Cytowane przez
Cytowane przez
Rok
Exploring the MHC-peptide matrix of central tolerance in the human thymus
E Adamopoulou, S Tenzer, N Hillen, P Klug, IA Rota, S Tietz, M Gebhardt, ...
Nature communications 4 (1), 2039, 2013
1052013
The histone deacetylase inhibitor trichostatin a promotes apoptosis and antitumor immunity in glioblastoma cells
E Hoering, O Podlech, B Silkenstedt, IA Rota, E Adamopoulou, ...
Anticancer research 33 (4), 1351-1360, 2013
612013
PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function
M Morotti, AJ Grimm, HC Hope, M Arnaud, M Desbuisson, N Rayroux, ...
Nature, 1-9, 2024
542024
FOXN1 deficient nude severe combined immunodeficiency
IA Rota, F Dhalla
Orphanet journal of rare diseases 12, 1-12, 2017
532017
Mechanistic drivers of Müllerian duct development and differentiation into the oviduct
L Santana Gonzalez, IA Rota, M Artibani, M Morotti, Z Hu, N Wietek, ...
Frontiers in cell and developmental biology 9, 605301, 2021
352021
Isolation of myeloid dendritic cells and epithelial cells from human thymus
C Stoeckle, IA Rota, E Tolosa, C Haller, A Melms, E Adamopoulou
Journal of visualized experiments: JoVE, 50951, 2013
312013
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells
J Corria-Osorio, SJ Carmona, E Stefanidis, M Andreatta, Y Ortiz-Miranda, ...
Nature Immunology 24 (5), 869-883, 2023
302023
Expanding the nude SCID/CID phenotype associated with FOXN1 homozygous, compound heterozygous, or heterozygous mutations
G Giardino, SO Sharapova, P Ciznar, F Dhalla, L Maragliano, ...
Journal of Clinical Immunology 41, 756-768, 2021
222021
Keratinocyte growth factor impairs human thymic recovery from lymphopenia
AJ Coles, L Azzopardi, O Kousin-Ezewu, HK Mullay, SAJ Thompson, ...
JCI insight 4 (12), 2019
222019
The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity
JA Newman, H Aitkenhead, AE Gavard, IA Rota, AE Handel, ...
Journal of Biological Chemistry 295 (10), 2948-2958, 2020
212020
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency
IA Rota, AE Handel, S Maio, F Klein, F Dhalla, ME Deadman, S Cheuk, ...
Science Advances 7 (49), eabj9247, 2021
192021
Developmental dynamics of the neural crest–mesenchymal axis in creating the thymic microenvironment
AE Handel, S Cheuk, F Dhalla, S Maio, T Hübscher, I Rota, ME Deadman, ...
Science Advances 8 (19), eabm9844, 2022
122022
Infection risk dictates immunological divergence among populations in a Mediterranean lizard
K Sagonas, IA Rota, OE Tsitsilonis, P Pafilis, ED Valakos
Journal of Evolutionary Biology 29 (9), 1680-1688, 2016
102016
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
BE Oftedal, S Maio, AE Handel, MPJ White, D Howie, S Davis, N Prevot, ...
Communications biology 4 (1), 681, 2021
92021
The structural basis for forkhead box family specificity revealed by the crystal structure of human FOXN1 in complex with DNA
JA Newman, H Aitkenhead, A Gravard, IA Rota, AE Handel, GA Hollander, ...
bioRxiv, 428011, 2018
62018
Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT
AR Smith, IA Rota, S Maio, MJ Massaad, TC Lund, LD Notarangelo, ...
Blood Advances 1 (23), 2083-2087, 2017
42017
A FOXN1 mutation competitively displaces wild-type FOXN1 from higher-order nuclear condensates to cause immunodeficiency
IA Rota, AE Handel, F Klein, S Maio, F Dhalla, ME Deadman, S Cheuk, ...
bioRxiv, 2021.03. 28.437237, 2021
2021
Functional characterisation of a novel heterozygous mutation in the transcriptional activation domain of the human FOXN1 gene
I Rota
University of Oxford, 2019
2019
Exploring the basis of central tolerance: what do dendritic cells present in the human thymus?
E Adamopoulou, S Tenzer, N Hillen, P Klug, IA Rota, S Tietz, M Gebhardt, ...
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