MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate AS Ireland, AM Micinski, DW Kastner, B Guo, SJ Wait, KB Spainhower, ... Cancer cell 38 (1), 60-78. e12, 2020 | 383 | 2020 |
The lineage-defining transcription factors SOX2 and NKX2-1 determine lung cancer cell fate and shape the tumor immune microenvironment G Mollaoglu, A Jones, SJ Wait, A Mukhopadhyay, S Jeong, R Arya, ... Immunity 49 (4), 764-779. e9, 2018 | 183 | 2018 |
MYC-driven small-cell lung cancer is metabolically distinct and vulnerable to arginine depletion MD Chalishazar, SJ Wait, F Huang, AS Ireland, A Mukhopadhyay, Y Lee, ... Clinical Cancer Research 25 (16), 5107-5121, 2019 | 174 | 2019 |
New approaches to SCLC therapy: from the laboratory to the clinic JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ... Journal of Thoracic Oncology 15 (4), 520-540, 2020 | 170 | 2020 |
ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer RR Olsen, AS Ireland, DW Kastner, SM Groves, KB Spainhower, K Pozo, ... Genes & Development 35 (11-12), 847-869, 2021 | 54 | 2021 |
Opto-MASS: a high-throughput engineering platform for genetically encoded fluorescent sensors enabling all-optical in vivo detection of monoamines and opioids M Rappleye, A Gordon-Fennel, DC Castro, AK Matarasso, CA Zamorano, ... BioRxiv, 2022.06. 01.494241, 2022 | 13 | 2022 |
Inhibition of karyopherin β1-mediated nuclear import disrupts oncogenic lineage-defining transcription factor activity in small cell lung cancer DP Kelenis, KE Rodarte, RK Kollipara, K Pozo, SP Choudhuri, ... Cancer research 82 (17), 3058-3073, 2022 | 12 | 2022 |
Machine learning-guided engineering of genetically encoded fluorescent calcium indicators SJ Wait, M Expòsit, S Lin, M Rappleye, JD Lee, SA Colby, L Torp, ... Nature Computational Science 4 (3), 224-236, 2024 | 6 | 2024 |
Optogenetic microwell array screening system: a high-throughput engineering platform for genetically encoded fluorescent indicators M Rappleye, SJ Wait, JD Lee, JC Siebart, L Torp, N Smith, J Muster, ... ACS sensors 8 (11), 4233-4244, 2023 | 6 | 2023 |
Far-red and sensitive sensor for monitoring real time H2O2 dynamics with subcellular resolution and in multi-parametric imaging applications JD Lee, A Nguyen, ZR Jin, A Moghadasi, CE Gibbs, SJ Wait, KM Evitts, ... bioRxiv, 2024 | 3 | 2024 |
Machine learning ensemble directed engineering of genetically encoded fluorescent calcium indicators SJ Wait, M Rappleye, JD Lee, ME Goy, N Smith, A Berndt Research Square, 2023 | 2 | 2023 |
ASCL1 represses a latent osteogenic program in small cell lung Cancer in multiple cells of origin RR Olsen, DW Kastner, AS Ireland, SM Groves, K Pozo, CP Whitney, ... bioRxiv, 2020.11. 11.362632, 2020 | 1 | 2020 |
IA21 ASCL1 represses a latent osteogenic program in small-cell lung cancer arising from multiple cells of origin RR Olsen, DW Kastner, AS Ireland, K Pozo, CP Whitney, MR Guthrie, ... Journal of Thoracic Oncology 15 (2), S7, 2020 | 1 | 2020 |
Far-red and sensitive sensor for monitoring real time H2O2 dynamics with subcellular resolution and in multi-parametric imaging applications A Berndt, J Lee, A Nguyen, Z Jin, A Moghadasi, C Gibbs, S Wait, K Evitts, ... Research Square, 2024 | | 2024 |
Application of Machine Learning to Direct Calcium Indicator Engineering SJ Wait, JD Lee, M Rappleye, A Berndt Optics and the Brain, BM4B. 2, 2023 | | 2023 |
Abstract PO-120: MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate AS Ireland, AM Micinski, DW Kastner, B Guo, SJ Wait, KB Spainhower, ... Cancer Research 80 (21_Supplement), PO-120-PO-120, 2020 | | 2020 |
Abstract B72: Lineage specifiers SOX2 and NKX2-1 inversely regulate tumor cell fate and neutrophil recruitment in lung cancer G Mollaoglu, A Jones, S Wait, A Mukhopadhyay, S Jeong, R Arya, ... Cancer Immunology Research 8 (4_Supplement), B72-B72, 2020 | | 2020 |
Lineage specifiers SOX2 and NKX2-1 inversely regulate tumor cell fate and neutrophil recruitment in lung cancer. G Mollaoglu, A Jones, S Wait, A Mukhopadhyay, S Jeong, R Arya, ... CANCER IMMUNOLOGY RESEARCH 8 (4), 117-117, 2020 | | 2020 |
A08 MYC-Driven SCLC Has Unique Metabolic Vulnerabilities SJ Wait, MD Chalishazar, F Huang, JS Bomalaski, RJ DeBerardinis, ... Journal of Thoracic Oncology 15 (2), S14, 2020 | | 2020 |
New Approaches to SCLC Therapy: From the Laboratory JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ... | | 2020 |