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David A Brown
David A Brown
Senior Vice President, Stealth BioTherapeutics
Zweryfikowany adres z stealthbt.com
Tytuł
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Cytowane przez
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Mitochondrial function as a therapeutic target in heart failure
DA Brown, JB Perry, ME Allen, HN Sabbah, BL Stauffer, SR Shaikh, ...
Nature Reviews Cardiology 14 (4), 238-250, 2017
7462017
Cardiac mitochondria and arrhythmias
DA Brown, B O'Rourke
Cardiovascular research 88 (2), 241-249, 2010
2552010
Short-term treadmill running in the rat: what kind of stressor is it?
DA Brown, MS Johnson, CJ Armstrong, JM Lynch, NM Caruso, LB Ehlers, ...
Journal of applied physiology 103 (6), 1979-1985, 2007
2512007
Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart
DA Brown, KN Jew, GC Sparagna, TI Musch, RL Moore
Journal of Applied Physiology 95 (6), 2510-2518, 2003
2162003
Susceptibility of the heart to ischaemia–reperfusion injury and exercise‐induced cardioprotection are sex‐dependent in the rat
DA Brown, JM Lynch, CJ Armstrong, NM Caruso, LB Ehlers, MS Johnson, ...
The Journal of physiology 564 (2), 619-630, 2005
2122005
Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat
DA Brown, AJ Chicco, KN Jew, MS Johnson, JM Lynch, PA Watson, ...
The Journal of physiology 569 (3), 913-924, 2005
1992005
Reduction of ischemia/reperfusion injury with bendavia, a mitochondria‐targeting cytoprotective peptide
RA Kloner, SL Hale, W Dai, RC Gorman, T Shuto, KJ Koomalsingh, ...
Journal of the American Heart Association 1 (3), e001644, 2012
1892012
Exercise-induced cardiac preconditioning: how exercise protects your achy-breaky heart
CR Frasier, RL Moore, DA Brown
Journal of Applied Physiology 111 (3), 905-915, 2011
1622011
From mitochondrial dynamics to arrhythmias
MA Aon, S Cortassa, FG Akar, DA Brown, L Zhou, B O’rourke
The international journal of biochemistry & cell biology 41 (10), 1940-1948, 2009
1372009
Cardiac arrhythmias induced by glutathione oxidation can be inhibited by preventing mitochondrial depolarization
DA Brown, MA Aon, CR Frasier, RC Sloan, AH Maloney, EJ Anderson, ...
Journal of molecular and cellular cardiology 48 (4), 673-679, 2010
1362010
Mitochondrial permeability transition in the diabetic heart: contributions of thiol redox state and mitochondrial calcium to augmented reperfusion injury
RC Sloan, F Moukdar, CR Frasier, HD Patel, PA Bostian, RM Lust, ...
Journal of molecular and cellular cardiology 52 (5), 1009-1018, 2012
1342012
Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise
PA Watson, JEB Reusch, SA McCune, LA Leinwand, SW Luckey, ...
American journal of physiology-heart and circulatory physiology 293 (1 …, 2007
1192007
Effects of 4′-chlorodiazepam on cellular excitation–contraction coupling and ischaemia–reperfusion injury in rabbit heart
DA Brown, MA Aon, FG Akar, T Liu, N Sorarrain, B O’Rourke
Cardiovascular research 79 (1), 141-149, 2008
1162008
Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia
DA Brown, SL Hale, CP Baines, CL Rio, RL Hamlin, Y Yueyama, ...
Journal of cardiovascular pharmacology and therapeutics 19 (1), 121-132, 2014
1122014
Role of mitochondrial dysfunction in cardiac glycoside toxicity
T Liu, DA Brown, B O'Rourke
Journal of molecular and cellular cardiology 49 (5), 728-736, 2010
1092010
Sex differences in myocardial infarct size are abolished by sarcolemmal KATP channel blockade in rat
MS Johnson, RL Moore, DA Brown
American Journal of Physiology-Heart and Circulatory Physiology 290 (6 …, 2006
1092006
The role of cardiolipin concentration and acyl chain composition on mitochondrial inner membrane molecular organization and function
ER Pennington, K Funai, DA Brown, SR Shaikh
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019
1062019
Redox-dependent increases in glutathione reductase and exercise preconditioning: role of NADPH oxidase and mitochondria
CR Frasier, F Moukdar, HD Patel, RC Sloan, LM Stewart, RJ Alleman, ...
Cardiovascular research 98 (1), 47-55, 2013
1062013
Exercise increases SOCS‐3 expression in rat skeletal muscle: potential relationship to IL‐6 expression
EE Spangenburg, DA Brown, MS Johnson, RL Moore
The Journal of Physiology 572 (3), 839-848, 2006
1002006
The “Goldilocks Zone” from a redox perspective—Adaptive vs. deleterious responses to oxidative stress in striated muscle
RJ Alleman, LA Katunga, MAM Nelson, DA Brown, EJ Anderson
Frontiers in physiology 5, 358, 2014
972014
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