Accurate prediction of protein structures and interactions using a three-track neural network M Baek, F DiMaio, I Anishchenko, J Dauparas, S Ovchinnikov, GR Lee, ... Science 373 (6557), 871-876, 2021 | 4489 | 2021 |
BAP1 loss defines a new class of renal cell carcinoma S Peña-Llopis, S Vega-Rubín-de-Celis, A Liao, N Leng, A Pavía-Jiménez, ... Nature genetics 44 (7), 751-759, 2012 | 1033 | 2012 |
Identification of a candidate therapeutic autophagy-inducing peptide S Shoji-Kawata, R Sumpter, M Leveno, GR Campbell, Z Zou, L Kinch, ... Nature 494 (7436), 201-206, 2013 | 842 | 2013 |
Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote Z Zhao, Y Tuakli-Wosornu, TA Lagace, L Kinch, NV Grishin, JD Horton, ... The American Journal of Human Genetics 79 (3), 514-523, 2006 | 792 | 2006 |
A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis S He, C McPhaul, JZ Li, R Garuti, L Kinch, NV Grishin, JC Cohen, ... Journal of Biological Chemistry 285 (9), 6706-6715, 2010 | 750 | 2010 |
Structure prediction for CASP8 with all‐atom refinement using Rosetta S Raman, R Vernon, J Thompson, M Tyka, R Sadreyev, J Pei, D Kim, ... Proteins: Structure, Function, and Bioinformatics 77 (S9), 89-99, 2009 | 614 | 2009 |
EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance Y Wei, Z Zou, N Becker, M Anderson, R Sumpter, G Xiao, L Kinch, ... Cell 154 (6), 1269-1284, 2013 | 587 | 2013 |
Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer Y Wang, PJ Kuan, C Xing, JT Cronkhite, F Torres, RL Rosenblatt, ... The American Journal of Human Genetics 84 (1), 52-59, 2009 | 567 | 2009 |
Secreted kinase phosphorylates extracellular proteins that regulate biomineralization VS Tagliabracci, JL Engel, J Wen, SE Wiley, CA Worby, LN Kinch, J Xiao, ... Science 336 (6085), 1150-1153, 2012 | 492 | 2012 |
AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling ML Yarbrough, Y Li, LN Kinch, NV Grishin, HL Ball, K Orth science 323 (5911), 269-272, 2009 | 491 | 2009 |
An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis AA Salahudeen, JW Thompson, JC Ruiz, HW Ma, LN Kinch, Q Li, ... Science 326 (5953), 722-726, 2009 | 470 | 2009 |
Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response X Jiang, LN Kinch, CA Brautigam, X Chen, F Du, NV Grishin, ZJ Chen Immunity 36 (6), 959-973, 2012 | 453 | 2012 |
ECOD: an evolutionary classification of protein domains H Cheng, RD Schaeffer, Y Liao, LN Kinch, J Pei, S Shi, BH Kim, ... PLoS computational biology 10 (12), e1003926, 2014 | 387 | 2014 |
Spectrum of diverse genomic alterations define non–clear cell renal carcinoma subtypes S Durinck, EW Stawiski, A Pavía-Jiménez, Z Modrusan, P Kapur, ... Nature genetics 47 (1), 13-21, 2015 | 375 | 2015 |
A single kinase generates the majority of the secreted phosphoproteome VS Tagliabracci, SE Wiley, X Guo, LN Kinch, E Durrant, J Wen, J Xiao, ... Cell 161 (7), 1619-1632, 2015 | 341 | 2015 |
C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation Y Liu, X Ye, F Jiang, C Liang, D Chen, J Peng, LN Kinch, NV Grishin, ... Science 325 (5941), 750-753, 2009 | 311 | 2009 |
Crystal structure of the human sterol transporter ABCG5/ABCG8 JY Lee, LN Kinch, DM Borek, J Wang, J Wang, IL Urbatsch, XS Xie, ... Nature 533 (7604), 561-564, 2016 | 296 | 2016 |
Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop RE Infante, A Radhakrishnan, L Abi-Mosleh, LN Kinch, ML Wang, ... Journal of Biological Chemistry 283 (2), 1064-1075, 2008 | 283 | 2008 |
Large-scale determination of previously unsolved protein structures using evolutionary information S Ovchinnikov, L Kinch, H Park, Y Liao, J Pei, DE Kim, H Kamisetty, ... elife 4, e09248, 2015 | 282 | 2015 |
Structure, lipid scrambling activity and role in autophagosome formation of ATG9A S Maeda, H Yamamoto, LN Kinch, CM Garza, S Takahashi, C Otomo, ... Nature structural & molecular biology 27 (12), 1194-1201, 2020 | 263 | 2020 |