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Liselot Dewachter
Liselot Dewachter
F.R.S.-FNRS & de Duve Institute, UCLouvain (Belgium)
Zweryfikowany adres z uclouvain.be
Tytuł
Cytowane przez
Cytowane przez
Rok
Obg and membrane depolarization are part of a microbial bet-hedging strategy that leads to antibiotic tolerance
N Verstraeten, WJ Knapen, CI Kint, V Liebens, B Van den Bergh, ...
Molecular cell 59 (1), 9-21, 2015
3382015
Bacterial heterogeneity and antibiotic survival: understanding and combatting persistence and heteroresistance
L Dewachter, M Fauvart, J Michiels
Molecular cell 76 (2), 255-267, 2019
1972019
The persistence-inducing toxin HokB forms dynamic pores that cause ATP leakage
D Wilmaerts, M Bayoumi, L Dewachter, W Knapen, JT Mika, J Hofkens, ...
MBio 9 (4), 10.1128/mbio. 00744-18, 2018
872018
An integrative view of cell cycle control in Escherichia coli
L Dewachter, N Verstraeten, M Fauvart, J Michiels
FEMS Microbiology Reviews 42 (2), 116-136, 2018
862018
HokB monomerization and membrane repolarization control persister awakening
D Wilmaerts, L Dewachter, PJ De Loose, C Bollen, N Verstraeten, ...
Molecular cell 75 (5), 1031-1042. e4, 2019
742019
The dynamic transition of persistence toward the viable but nonculturable state during stationary phase is driven by protein aggregation
L Dewachter, C Bollen, D Wilmaerts, E Louwagie, P Herpels, P Matthay, ...
MBio 12 (4), 10.1128/mbio. 00703-21, 2021
662021
Protein aggregation as a bacterial strategy to survive antibiotic treatment
C Bollen, L Dewachter, J Michiels
Frontiers in molecular biosciences 8, 669664, 2021
582021
Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis
B Van den Bergh, H Schramke, JE Michiels, TEP Kimkes, JL Radzikowski, ...
Nature communications 13 (1), 546, 2022
372022
Deep mutational scanning of essential bacterial proteins can guide antibiotic development
L Dewachter, AN Brooks, K Noon, C Cialek, A Clark-ElSayed, T Schalck, ...
nature communications 14 (1), 241, 2023
292023
A single-amino-acid substitution in Obg activates a new programmed cell death pathway in Escherichia coli
L Dewachter, N Verstraeten, D Monteyne, CI Kint, W Versées, ...
MBio 6 (6), 10.1128/mbio. 01935-15, 2015
282015
A mutant isoform of ObgE causes cell death by interfering with cell division
L Dewachter, N Verstraeten, M Jennes, T Verbeelen, J Biboy, D Monteyne, ...
Frontiers in microbiology 8, 1193, 2017
212017
Reactive oxygen species do not contribute to ObgE*-mediated programmed cell death
L Dewachter, P Herpels, N Verstraeten, M Fauvart, J Michiels
Scientific Reports 6 (1), 33723, 2016
202016
Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq
L Dewachter, J Dénéréaz, X Liu, V de Bakker, C Costa, M Baldry, ...
Elife 11, e75607, 2022
192022
Biochemical determinants of ObgE‐mediated persistence
N Verstraeten, S Gkekas, CI Kint, B Deckers, B Van den Bergh, P Herpels, ...
Molecular microbiology 112 (5), 1593-1608, 2019
102019
The bacterial cell cycle checkpoint protein Obg and its role in programmed cell death
L Dewachter, N Verstraeten, M Fauvart, J Michiels
Microbial cell 3 (6), 255, 2016
92016
GTP binding is necessary for the activation of a toxic mutant isoform of the essential GTPase ObgE
L Dewachter, B Deckers, E Martin, P Herpels, S Gkekas, W Versées, ...
International journal of molecular sciences 21 (1), 16, 2019
42019
YbiB: a novel interactor of the GTPase ObgE
B Deckers, S Vercauteren, V De Kock, C Martin, T Lazar, P Herpels, ...
Nucleic acids research 51 (7), 3420-3435, 2023
32023
Composition and liquid-to-solid maturation of protein aggregates contribute to bacterial dormancy development and recovery
C Bollen, S Louwagie, F Deroover, W Duverger, L Khodaparast, ...
Nature Communications 16 (1), 1046, 2025
2025
The role of the essential GTPase ObgE in regulating lipopolysaccharide synthesis in Escherichia coli
L Dewachter, B Deckers, I Mares-Mejía, E Louwagie, S Vercauteren, ...
Nature communications 15 (1), 9684, 2024
2024
The rise and future of CRISPR-based approaches for high-throughput genomics
S Vercauteren, S Fiesack, L Maroc, N Verstraeten, L Dewachter, ...
FEMS microbiology reviews 48 (5), fuae020, 2024
2024
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