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SAMUEL M. LEVI
SAMUEL M. LEVI
Zweryfikowany adres z pfizer.com
Tytuł
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Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma
XH Ma, SF Piao, S Dey, Q Mcafee, G Karakousis, J Villanueva, LS Hart, ...
The Journal of clinical investigation 124 (3), 1406-1417, 2014
4872014
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
Q McAfee, Z Zhang, A Samanta, SM Levi, XH Ma, S Piao, JP Lynch, ...
Proceedings of the National Academy of Sciences 109 (21), 8253-8258, 2012
4442012
A unified approach to targeting the lysosome's degradative and growth signaling roles
VW Rebecca, MC Nicastri, N McLaughlin, C Fennelly, Q McAfee, ...
Cancer discovery 7 (11), 1266-1283, 2017
1792017
Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells
VM Hubbard-Lucey, Y Shono, K Maurer, ML West, NV Singer, ...
Immunity 41 (4), 579-591, 2014
1102014
Highly selective β-mannosylations and β-rhamnosylations catalyzed by bis-thiourea
Q Li, SM Levi, EN Jacobsen
Journal of the American Chemical Society 142 (27), 11865-11872, 2020
872020
Site-selective, stereocontrolled glycosylation of minimally protected sugars
Q Li, SM Levi, CC Wagen, AE Wendlandt, EN Jacobsen
Nature 608 (7921), 74-79, 2022
732022
Autophagy inhibition enhances sunitinib efficacy in clear cell ovarian carcinoma
L DeVorkin, M Hattersley, P Kim, J Ries, J Spowart, MS Anglesio, SM Levi, ...
Molecular Cancer Research 15 (3), 250-258, 2017
722017
Catalytic activation of glycosyl phosphates for stereoselective coupling reactions
SM Levi, Q Li, AR Rötheli, EN Jacobsen
Proceedings of the National Academy of Sciences 116 (1), 35-39, 2019
712019
Palladium-catalyzed C− CN activation for intramolecular cyanoesterification of alkynes
NR Rondla, SM Levi, JM Ryss, RA Vanden Berg, CJ Douglas
Organic Letters 13 (8), 1940-1943, 2011
602011
Discovery of diaminopyrimidine carboxamide HPK1 inhibitors as preclinical immunotherapy tool compounds
BA Vara, SM Levi, A Achab, DA Candito, X Fradera, CA Lesburg, ...
ACS Medicinal Chemistry Letters 12 (4), 653-661, 2021
402021
Reductive sp3–sp2 Coupling Reactions Enable Late-Stage Modification of Pharmaceuticals
KM Mennie, BA Vara, SM Levi
Organic Letters 22 (2), 556-559, 2020
202020
Unifying catalysis framework to dissect proteasomal degradation paradigms
FP Rodriguez-Rivera, SM Levi
ACS Central Science 7 (7), 1117-1125, 2021
192021
Catalyst‐Controlled Glycosylation
SM Levi, EN Jacobsen*
Organic Reactions, 801-852, 2004
142004
Diaminopyrimidine carboxamide inhibitors of hpk1
A Achab, DA Candito, A Donofrio, X Fradera, S Kawamura, SM Levi, B Li, ...
US Patent App. 18/251,259, 2023
12023
Site-Selective, Stereocontrolled Glycosylation Catalyzed by Bis-Thioureas
Q Li, SM Levi, CC Wagen, AE Wendlandt, EN Jacobsen
12022
Site-Selective, Stereocontrolled Glycosylation Catalyzed by Bis-Thioureas
E Jacobsen, Q Li, S Levi, C Wagen, A Wendlandt
2022
Catalyst-controlled regio-and stereoselective glycosylation
Q Li, S Levi, E Jacobsen
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Stereo-and Regioselective Glycosylation
SM Levi
Harvard University, 2019
2019
Discovery of a novel series of aminopyrazine-based A2a antagonists for the treatment of Parkinson's disease: Integration of an intramolecular H-bonding strategy in the design …
R Kuang, H Wu, A Ali, P Ting, S Levi, M Lo, E Metzger, T Henderson, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
The Design and Synthesis of Chloroquine Derivatives to Block Autophagy in Cancer Cells
SM Levi
University of Pennsylvania, 2014
2014
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