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Xiaolan Deng
Xiaolan Deng
City of Hope, Beckman Research Institute, Department of System Biology
Zweryfikowany adres z coh.org
Tytuł
Cytowane przez
Cytowane przez
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Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
H Huang, H Weng, W Sun, X Qin, H Shi, H Wu, BS Zhao, A Mesquita, ...
Nature cell biology 20 (3), 285-295, 2018
23662018
R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling
R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ...
Cell 172 (1), 90-105. e23, 2018
9862018
METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification
H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ...
Cell stem cell 22 (2), 191-205. e9, 2018
8892018
RNA N6-methyladenosine modification in cancers: current status and perspectives
X Deng, R Su, H Weng, H Huang, Z Li, J Chen
Cell research 28 (5), 507-517, 2018
6882018
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally
H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ...
Nature 567 (7748), 414-419, 2019
5882019
Targeting FTO suppresses cancer stem cell maintenance and immune evasion
R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ...
Cancer cell 38 (1), 79-96. e11, 2020
5852020
RNA demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia
C Shen, Y Sheng, AC Zhu, S Robinson, X Jiang, L Dong, H Chen, R Su, ...
Cell stem cell 27 (1), 64-80. e9, 2020
3212020
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
Y Qing, L Dong, L Gao, C Li, Y Li, L Han, E Prince, B Tan, X Deng, ...
Molecular cell 81 (5), 922-939. e9, 2021
2442021
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
R Su, L Dong, Y Li, M Gao, PC He, W Liu, J Wei, Z Zhao, L Gao, L Han, ...
Nature cell biology 24 (2), 205-216, 2022
2232022
Role of N6-methyladenosine modification in cancer
X Deng, R Su, X Feng, M Wei, J Chen
Current opinion in genetics & development 48, 1-7, 2018
2082018
The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
H Weng, F Huang, Z Yu, Z Chen, E Prince, Y Kang, K Zhou, W Li, J Hu, ...
Cancer Cell 40 (12), 1566-1582. e10, 2022
1602022
The roles and implications of RNA m6A modification in cancer
X Deng, Y Qing, D Horne, H Huang, J Chen
Nature Reviews Clinical Oncology 20 (8), 507-526, 2023
1492023
Critical enzymatic functions of FTO in obesity and cancer
X Deng, R Su, S Stanford, J Chen
Frontiers in endocrinology 9, 396, 2018
1402018
FTO in cancer: functions, molecular mechanisms, and therapeutic implications
Y Li, R Su, X Deng, Y Chen, J Chen
Trends in cancer 8 (7), 598-614, 2022
1342022
Cancer precision medicine: from cancer screening to drug selection and personalized immunotherapy
X Deng, Y Nakamura
Trends in pharmacological sciences 38 (1), 15-24, 2017
942017
RNA-binding proteins in regulating mRNA stability and translation: roles and mechanisms in cancer
W Li, X Deng, J Chen
Seminars in cancer biology 86, 664-677, 2022
802022
RNA modifications in cancer: functions, mechanisms, and therapeutic implications
H Huang, H Weng, X Deng, J Chen
Annual Review of Cancer Biology 4 (1), 221-240, 2020
802020
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
L Han, L Dong, K Leung, Z Zhao, Y Li, L Gao, Z Chen, J Xue, Y Qing, W Li, ...
Cell Stem Cell 30 (1), 52-68. e13, 2023
762023
QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
Z Zhao, Y Qing, L Dong, L Han, D Wu, Y Li, W Li, J Xue, K Zhou, M Sun, ...
Cell 186 (15), 3208-3226. e27, 2023
692023
Impact of temperature exposure on stability of drugs in a real-world out-of-hospital setting
S De Winter, P Vanbrabant, NTT Vi, X Deng, I Spriet, A Van Schepdael, ...
Annals of emergency medicine 62 (4), 380-387. e1, 2013
672013
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