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Paula Morales
Paula Morales
Zweryfikowany adres z iqm.csic.es - Strona główna
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Cannabinoid Ligands Targeting TRP Channels
C Muller, P Morales, P Reggio
Frontiers in Molecular Neuroscience 111, Article 487, 2019
6142019
Molecular targets of the phytocannabinoids: a complex picture
P Morales, DP Hurst, PH Reggio
Phytocannabinoids: Unraveling the complex Chemistry and Pharmacology of …, 2017
6112017
An overview on medicinal chemistry of synthetic and natural derivatives of cannabidiol
P Morales, PH Reggio, N Jagerovic
Frontiers in pharmacology 8, 422, 2017
2092017
An Update on Non-CB1, Non-CB2 Cannabinoid Related G-Protein-Coupled Receptors
P Morales, PH Reggio
Cannabis and cannabinoid research 2 (1), 265-273, 2017
2052017
Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders
G Navarro, P Morales, C Rodríguez-Cueto, J Fernández-Ruiz, ...
Frontiers in Neuroscience 10, 406, 2016
1642016
Allosteric Modulators of the CB1 Cannabinoid Receptor: A Structural Update Review
P Morales, P Goya, N Jagerovic, L Hernandez-Folgado
Cannabis and Cannabinoid Research 1 (1), 22-30, 2016
1112016
Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes
G Navarro, I Reyes-Resina, R Rivas-Santisteban, VS de Medina, ...
Biochemical pharmacology 157, 148-158, 2018
992018
Structural Insights into CB1 Receptor Biased Signaling
R Al-Zoubi, P Morales, P Reggio
International Journal of Molecular Sciences 20 (8), 1837, 2019
922019
Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update
P Morales, L Hernandez-Folgado, P Goya, N Jagerovic
Expert opinion on therapeutic patents 26 (7), 843-856, 2016
912016
Emerging strategies targeting CB 2 cannabinoid receptor: Biased agonism and allosterism
P Morales, P Goya, N Jagerovic
Biochemical Pharmacology 157, 8-17, 2018
592018
Towards a better understanding of the cannabinoid-related orphan receptors GPR3, GPR6, and GPR12
P Morales, I Isawi, PH Reggio
Drug metabolism reviews 50 (1), 74-93, 2018
582018
Synthetic cannabinoid quinones: Preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity
P Morales, D Vara, M Gomez-Canas, MC Zúñiga, C Olea-Azar, P Goya, ...
European Journal of Medicinal Chemistry 70, 111-119, 2013
582013
Therapeutic exploitation of GPR18: beyond the cannabinoids? Miniperspective
P Morales, A Lago-Fernandez, DP Hurst, N Sotudeh, E Brailoiu, ...
Journal of medicinal chemistry 63 (23), 14216-14227, 2020
552020
Advances towards the discovery of GPR55 ligands
P Morales, N Jagerovic
Current medicinal chemistry 23 (20), 2087-2100, 2016
532016
Chromenopyrazole, a versatile cannabinoid scaffold with in vivo activity in a model of multiple sclerosis
P Morales, M Gómez-Cañas, G Navarro, DP Hurst, FJ Carrillo-Salinas, ...
Journal of medicinal chemistry 59 (14), 6753-6771, 2016
472016
Selective, Nontoxic CB2 Cannabinoid o-Quinone with in Vivo Activity against Triple-Negative Breast Cancer
P Morales, S Blasco-Benito, C Andradas, M Gómez-Cañas, JM Flores, ...
Journal of medicinal chemistry 58 (5), 2256-2264, 2015
472015
Potential metabolic and behavioural roles of the putative endocannabinoid receptors GPR18, GPR55 and GPR119 in feeding
RE Ramírez-Orozco, R García-Ruiz, P Morales, CM Villalón, ...
Current neuropharmacology 17 (10), 947-960, 2019
462019
Chromenopyrazoles: Non‐psychoactive and Selective CB1 Cannabinoid Agonists with Peripheral Antinociceptive Properties
J Cumella, L Hernández‐Folgado, R Girón, E Sánchez, P Morales, ...
ChemMedChem 7 (3), 452-463, 2012
432012
Relevance of Peroxisome Proliferator Activated Receptors in Multitarget Paradigm Associated with the Endocannabinoid System
A Lago-Fernandez, S Zarzo-Arias, N Jagerovic, P Morales
International Journal of Molecular Sciences 22 (3), 1001, 2021
412021
A Molecular Modeling Approach to Identify Novel Inhibitors of the Major Facilitator Superfamily of Efflux Pump Transporters
S Zarate, P Morales, K Świderek, V Bolanos-Garcia, A Bastida
Antibiotics 8 (1), 25, 2019
412019
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