Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial S Ramakrishnan, DV Nicolau, B Langford, M Mahdi, H Jeffers, ... The Lancet Respiratory Medicine 9 (7), 763-772, 2021 | 471 | 2021 |
Cellular senescence as a mechanism and target in chronic lung diseases PJ Barnes, J Baker, LE Donnelly American journal of respiratory and critical care medicine 200 (5), 556-564, 2019 | 455 | 2019 |
Oxidative stress dependent microRNA-34a activation via PI3Kα reduces the expression of sirtuin-1 and sirtuin-6 in epithelial cells JR Baker, C Vuppusetty, T Colley, AI Papaioannou, P Fenwick, ... Scientific reports 6 (1), 35871, 2016 | 175 | 2016 |
MicroRNA-570 is a novel regulator of cellular senescence and inflammaging JR Baker, C Vuppusetty, T Colley, S Hassibi, PS Fenwick, LE Donnelly, ... The FASEB Journal 33 (2), 1605, 2018 | 88 | 2018 |
The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure S Yanagisawa, JR Baker, C Vuppusetty, T Koga, T Colley, P Fenwick, ... PloS one 13 (3), e0193921, 2018 | 71 | 2018 |
Decreased phosphatase PTEN amplifies PI3K signaling and enhances proinflammatory cytokine release in COPD S Yanagisawa, JR Baker, C Vuppusetty, P Fenwick, LE Donnelly, K Ito, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 313 (2 …, 2017 | 66 | 2017 |
Decreased serum sirtuin-1 in COPD S Yanagisawa, AI Papaioannou, A Papaporfyriou, JR Baker, ... Chest 152 (2), 343-352, 2017 | 61 | 2017 |
Senotherapy: a new horizon for COPD therapy JR Baker, LE Donnelly, PJ Barnes Chest 158 (2), 562-570, 2020 | 54 | 2020 |
Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis JR Baker, M Mahdi, DV Nicolau, S Ramakrishnan, PJ Barnes, JL Simpson, ... The Lancet Respiratory Medicine 10 (6), 545-556, 2022 | 53 | 2022 |
Downregulation of microRNA-126 augments DNA damage response in cigarette smokers and patients with chronic obstructive pulmonary disease KE Paschalaki, A Zampetaki, JR Baker, MA Birrell, RD Starke, MG Belvisi, ... American journal of respiratory and critical care medicine 197 (5), 665-668, 2018 | 46 | 2018 |
IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice CK Koss, CT Wohnhaas, JR Baker, C Tilp, M Przibilla, C Lerner, S Frey, ... Communications biology 4 (1), 172, 2021 | 44 | 2021 |
Autophagy in asthma and chronic obstructive pulmonary disease PJ Barnes, J Baker, LE Donnelly Clinical Science 136 (10), 733-746, 2022 | 37 | 2022 |
Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes J Baker, AMD Falconer, DJ Wilkinson, GN Europe-Finner, GJ Litherland, ... PloS one 13 (4), e0195864, 2018 | 36 | 2018 |
Cigarette smoke-induced impairment of autophagy in macrophages increases galectin-8 and inflammation Y Kono, T Colley, M To, AI Papaioannou, N Mercado, JR Baker, Y To, ... Scientific reports 11 (1), 335, 2021 | 34 | 2021 |
Update in chronic obstructive pulmonary disease 2019 P Alter, JR Baker, N Dauletbaev, LE Donnelly, C Pistenmaa, B Schmeck, ... American journal of respiratory and critical care medicine 202 (3), 348-355, 2020 | 33 | 2020 |
Hepcidin is essential for alveolar macrophage function and is disrupted by smoke in a murine chronic obstructive pulmonary disease model E Perez, JR Baker, S Di Giandomenico, P Kermani, J Parker, K Kim, ... The Journal of Immunology 205 (9), 2489-2498, 2020 | 18 | 2020 |
Virus-induced asthma exacerbations: SIRT1 targeted approach Y Fukuda, K Akimoto, T Homma, JR Baker, K Ito, PJ Barnes, H Sagara Journal of Clinical Medicine 9 (8), 2623, 2020 | 18 | 2020 |
Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease N Mercado, T Colley, JR Baker, C Vuppussetty, Y Kono, C Clarke, ... FASEB BioAdvances 1 (11), 688-705, 2019 | 18 | 2019 |
Leukocyte function in COPD: clinical relevance and potential for drug therapy JR Baker, LE Donnelly International journal of chronic obstructive pulmonary disease, 2227-2242, 2021 | 14 | 2021 |
Update in chronic obstructive pulmonary disease 2020 AI Ritchie, JR Baker, TM Parekh, JP Allinson, SP Bhatt, LE Donnelly, ... American journal of respiratory and critical care medicine 204 (1), 14-22, 2021 | 14 | 2021 |