Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR J Cehajic-Kapetanovic, K Xue, C Martinez-Fernandez de la Camara, ... Nature medicine 26 (3), 354-359, 2020 | 310 | 2020 |
Visual acuity after retinal gene therapy for choroideremia TL Edwards, JK Jolly, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ... New England Journal of Medicine 374 (20), 1996-1998, 2016 | 231 | 2016 |
First-in-human study of the safety and viability of intraocular robotic surgery TL Edwards, K Xue, HCM Meenink, MJ Beelen, GJL Naus, MP Simunovic, ... Nature biomedical engineering 2 (9), 649-656, 2018 | 215 | 2018 |
Deep-learning models for the detection and incidence prediction of chronic kidney disease and type 2 diabetes from retinal fundus images K Zhang, X Liu, J Xu, J Yuan, W Cai, T Chen, K Wang, Y Gao, S Nie, X Xu, ... Nature biomedical engineering 5 (6), 533-545, 2021 | 213 | 2021 |
The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2−/− ung−/− mice K Xue, C Rada, MS Neuberger The Journal of experimental medicine 203 (9), 2085-2094, 2006 | 213 | 2006 |
Assessment of the electronic retinal implant alpha AMS in restoring vision to blind patients with end-stage retinitis pigmentosa TL Edwards, CL Cottriall, K Xue, MP Simunovic, JD Ramsden, E Zrenner, ... Ophthalmology 125 (3), 432-443, 2018 | 201 | 2018 |
Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia K Xue, JK Jolly, AR Barnard, A Rudenko, AP Salvetti, MI Patrício, ... Nature medicine 24 (10), 1507-1512, 2018 | 196 | 2018 |
Technique of retinal gene therapy: delivery of viral vector into the subretinal space K Xue, M Groppe, AP Salvetti, RE MacLaren Eye 31 (9), 1308-1316, 2017 | 182 | 2017 |
Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1 SG Conticello, K Ganesh, K Xue, M Lu, C Rada, MS Neuberger Molecular cell 31 (4), 474-484, 2008 | 170 | 2008 |
Current status and future trends of clinical diagnoses via image-based deep learning J Xu, K Xue, K Zhang Theranostics 9 (25), 7556, 2019 | 107 | 2019 |
Characterizing the natural history of visual function in choroideremia using microperimetry and multimodal retinal imaging JK Jolly, K Xue, TL Edwards, M Groppe, RE MacLaren Investigative ophthalmology & visual science 58 (12), 5575-5583, 2017 | 96 | 2017 |
A deep-learning system predicts glaucoma incidence and progression using retinal photographs F Li, Y Su, F Lin, Z Li, Y Song, S Nie, J Xu, L Chen, S Chen, H Li, K Xue, ... The Journal of Clinical Investigation 132 (11), 2022 | 93 | 2022 |
Correlation of optical coherence tomography and autofluorescence in the outer retina and choroid of patients with choroideremia K Xue, M Oldani, JK Jolly, TL Edwards, M Groppe, SM Downes, ... Investigative Ophthalmology & Visual Science 57 (8), 3674-3684, 2016 | 83 | 2016 |
The spectrum of CHM gene mutations in choroideremia and their relationship to clinical phenotype MP Simunovic, JK Jolly, K Xue, TL Edwards, M Groppe, SM Downes, ... Investigative ophthalmology & visual science 57 (14), 6033-6039, 2016 | 82 | 2016 |
Optimized glycemic control of type 2 diabetes with reinforcement learning: a proof-of-concept trial G Wang, X Liu, Z Ying, G Yang, Z Chen, Z Liu, M Zhang, H Yan, Y Lu, ... Nature Medicine 29 (10), 2633-2642, 2023 | 80 | 2023 |
Antisense oligonucleotide therapeutics in clinical trials for the treatment of inherited retinal diseases K Xue, RE MacLaren Expert Opinion on Investigational Drugs 29 (10), 1163-1170, 2020 | 59 | 2020 |
A network meta-analysis of retreatment rates following bevacizumab, ranibizumab, aflibercept, and laser for retinopathy of prematurity E Chang, AS Josan, R Purohit, CK Patel, K Xue Ophthalmology 129 (12), 1389-1401, 2022 | 55 | 2022 |
Structural and functional recovery following limited iatrogenic macular detachment for retinal gene therapy MP Simunovic, K Xue, JK Jolly, RE MacLaren JAMA ophthalmology 135 (3), 234-241, 2017 | 54 | 2017 |
First-in-human robot-assisted subretinal drug delivery under local anesthesia J Cehajic-Kapetanovic, K Xue, TL Edwards, TC Meenink, MJ Beelen, ... American Journal of Ophthalmology 237, 104-113, 2022 | 52 | 2022 |
Deep-learning-enabled protein–protein interaction analysis for prediction of SARS-CoV-2 infectivity and variant evolution G Wang, X Liu, K Wang, Y Gao, G Li, DT Baptista-Hon, XH Yang, K Xue, ... Nature Medicine 29 (8), 2007-2018, 2023 | 51 | 2023 |