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Spencer Szczesny
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Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates
Z Gong, SE Szczesny, SR Caliari, EE Charrier, O Chaudhuri, X Cao, Y Lin, ...
Proceedings of the National Academy of Sciences 115 (12), E2686-E2695, 2018
2732018
Interfibrillar shear stress is the loading mechanism of collagen fibrils in tendon
SE Szczesny, DM Elliott
Acta biomaterialia 10 (6), 2582-2590, 2014
2072014
Biaxial tensile testing and constitutive modeling of human supraspinatus tendon
SE Szczesny, JM Peloquin, DH Cortes, JA Kadlowec, LJ Soslowsky, ...
992012
The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction
SE Szczesny, RL Mauck
Journal of Biomechanical Engineering 139 (2), 021006, 2017
822017
Mechanically induced chromatin condensation requires cellular contractility in mesenchymal stem cells
SJ Heo, WM Han, SE Szczesny, BD Cosgrove, DM Elliott, DA Lee, ...
Biophysical journal 111 (4), 864-874, 2016
752016
Investigating mechanisms of tendon damage by measuring multi-scale recovery following tensile loading
AH Lee, SE Szczesny, MH Santare, DM Elliott
Acta biomaterialia 57, 363-372, 2017
722017
Evidence that interfibrillar load transfer in tendon is supported by small diameter fibrils and not extrafibrillar tissue components
SE Szczesny, KL Fetchko, GR Dodge, DM Elliott
Journal of Orthopaedic Research 35 (10), 2127-2134, 2017
662017
Quantification of interfibrillar shear stress in aligned soft collagenous tissues via notch tension testing
SE Szczesny, JL Caplan, P Pedersen, DM Elliott
Scientific reports 5 (1), 14649, 2015
662015
Cross-linking chemistry of tyramine-modified hyaluronan hydrogels alters mesenchymal stem cell early attachment and behavior
C Loebel, SE Szczesny, BD Cosgrove, M Alini, M Zenobi-Wong, ...
Biomacromolecules 18 (3), 855-864, 2017
652017
Experimental and computational investigation of altered mechanical properties in myocardium after hydrogel injection
ET Kichula, H Wang, SM Dorsey, SE Szczesny, DM Elliott, JA Burdick, ...
Annals of biomedical engineering 42, 1546-1556, 2014
642014
Biaxial mechanics and inter‐lamellar shearing of stem‐cell seeded electrospun angle‐ply laminates for annulus fibrosus tissue engineering
TP Driscoll, RH Nakasone, SE Szczesny, DM Elliott, RL Mauck
Journal of orthopaedic research 31 (6), 864-870, 2013
622013
Regional variation in human supraspinatus tendon proteoglycans: decorin, biglycan, and aggrecan
PE Matuszewski, YL Chen, SE Szczesny, SP Lake, DM Elliott, ...
Connective tissue research 53 (5), 343-348, 2012
622012
Incorporating plasticity of the interfibrillar matrix in shear lag models is necessary to replicate the multiscale mechanics of tendon fascicles
SE Szczesny, DM Elliott
Journal of the mechanical behavior of biomedical materials 40, 325-338, 2014
582014
Crimped nanofibrous biomaterials mimic microstructure and mechanics of native tissue and alter strain transfer to cells
SE Szczesny, TP Driscoll, HY Tseng, PC Liu, SJ Heo, RL Mauck, ...
ACS biomaterials science & engineering 3 (11), 2869-2876, 2017
552017
Exposure to buffer solution alters tendon hydration and mechanics
BN Safa, KD Meadows, SE Szczesny, DM Elliott
Journal of biomechanics 61, 18-25, 2017
492017
Fatigue loading of tendon results in collagen kinking and denaturation but does not change local tissue mechanics
SE Szczesny, C Aeppli, A David, RL Mauck
Journal of biomechanics 71, 251-256, 2018
482018
Macroporous hydrogels for stable sequestration and sustained release of vascular endothelial growth factor and basic fibroblast growth factor using nucleic acid aptamers
L Abune, N Zhao, J Lai, B Peterson, S Szczesny, Y Wang
ACS biomaterials science & engineering 5 (5), 2382-2390, 2019
422019
Expansion of mesenchymal stem cells on electrospun scaffolds maintains stemness, mechano‐responsivity, and differentiation potential
SJ Heo, SE Szczesny, DH Kim, KS Saleh, RL Mauck
Journal of Orthopaedic Research® 36 (2), 808-815, 2018
402018
Altered lumbar spine structure, biochemistry, and biomechanical properties in a canine model of mucopolysaccharidosis type VII
LJ Smith, JT Martin, SE Szczesny, KP Ponder, ME Haskins, DM Elliott
Journal of Orthopaedic Research 28 (5), 616-622, 2010
382010
DTAF dye concentrations commonly used to measure microscale deformations in biological tissues alter tissue mechanics
SE Szczesny, RS Edelstein, DM Elliott
PloS one 9 (6), e99588, 2014
332014
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