| Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development Y Lu, F Shiau, W Yi, S Lu, Q Wu, JD Pearson, A Kallman, S Zhong, ... Developmental cell 53 (4), 473-491. e9, 2020 | 232 | 2020 |
| Binary pan-cancer classes with distinct vulnerabilities defined by pro-or anti-cancer YAP/TEAD activity JD Pearson, K Huang, M Pacal, SR McCurdy, S Lu, A Aubry, T Yu, ... Cancer Cell 39 (8), 1115-1134. e12, 2021 | 129 | 2021 |
| A glucose meter interface for point-of-care gene circuit-based diagnostics E Amalfitano, M Karlikow, M Norouzi, K Jaenes, S Cicek, F Masum, ... Nature Communications 12 (1), 724, 2021 | 97 | 2021 |
| CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities ES Knudsen, V Kumarasamy, R Nambiar, JD Pearson, P Vail, ... Cell reports 38 (9), 2022 | 89 | 2022 |
| Identification of two novel phenotypically distinct breast cancer cell subsets based on Sox2 transcription activity F Wu, J Zhang, P Wang, X Ye, K Jung, KM Bone, JD Pearson, RJ Ingham, ... Cellular signalling 24 (11), 1989-1998, 2012 | 53 | 2012 |
| NPM‐ALK: The prototypic member of a family of oncogenic fusion tyrosine kinases JD Pearson, JKH Lee, JTC Bacani, R Lai, RJ Ingham Journal of signal transduction 2012 (1), 123253, 2012 | 51 | 2012 |
| A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2 MM Aynaud, JJ Hernandez, S Barutcu, U Braunschweig, K Chan, ... Nature communications 12 (1), 1405, 2021 | 46 | 2021 |
| Aberrant expression and biological significance of Sox2, an embryonic stem cell transcriptional factor, in ALK-positive anaplastic large cell lymphoma P Gelebart, SA Hegazy, P Wang, KM Bone, M Anand, D Sharon, M Hitt, ... Blood cancer journal 2 (8), e82-e82, 2012 | 46 | 2012 |
| NPM-ALK and the JunB transcription factor regulate the expression of cytotoxic molecules in ALK-positive, anaplastic large cell lymphoma JD Pearson, JKH Lee, JTC Bacani, R Lai, RJ Ingham International journal of clinical and experimental pathology 4 (2), 124, 2011 | 40 | 2011 |
| Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods JD Pearson, D Trcka, S Lu, SJ Hyduk, M Jen, MM Aynaud, JJ Hernández, ... Virology journal 18 (1), 99, 2021 | 38* | 2021 |
| Functional genomics identifies new synergistic therapies for retinoblastoma A Aubry, JD Pearson, K Huang, I Livne-Bar, M Ahmad, M Jagadeesan, ... Oncogene 39 (31), 5338-5357, 2020 | 32 | 2020 |
| Targeting the ubiquitin–proteasome system using the UBA1 inhibitor TAK-243 is a potential therapeutic strategy for small-cell lung cancer S Majeed, MK Aparnathi, KCJ Nixon, V Venkatasubramanian, F Rahman, ... Clinical Cancer Research 28 (9), 1966-1978, 2022 | 28 | 2022 |
| Alpha-sarcin catalytic activity is not required for cytotoxicity SC Alford, JD Pearson, A Carette, RJ Ingham, PL Howard Bmc Biochemistry 10, 1-11, 2009 | 28 | 2009 |
| Translational feasibility and efficacy of nasal photodynamic disinfection of SARS-CoV-2 L Pires, BC Wilson, R Bremner, A Lang, J Larouche, R McDonald, ... Scientific reports 12 (1), 14438, 2022 | 22 | 2022 |
| Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application S Lu, D Duplat, P Benitez-Bolivar, C León, SD Villota, ... PLoS One 17 (5), e0268340, 2022 | 20 | 2022 |
| Expression of granzyme B sensitizes ALK+ ALCL tumour cells to apoptosis-inducing drugs JD Pearson, J Zhang, Z Wu, KD Thew, KJ Rowe, JTC Bacani, RJ Ingham Molecular cancer 13, 1-14, 2014 | 20 | 2014 |
| The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein JD Pearson, Z Mohammed, JTC Bacani, R Lai, RJ Ingham BMC cancer 12, 1-14, 2012 | 20 | 2012 |
| The NEMP family supports metazoan fertility and nuclear envelope stiffness Y Tsatskis, R Rosenfeld, JD Pearson, C Boswell, Y Qu, K Kim, L Fabian, ... Science Advances 6 (35), eabb4591, 2020 | 17 | 2020 |
| InVision: An optimized tissue clearing approach for three-dimensional imaging and analysis of intact rodent eyes A Gurdita, PEB Nickerson, NT Pokrajac, A Ortín-Martínez, ELS Tsai, ... Iscience 24 (8), 2021 | 13 | 2021 |
| Cleavage of the JunB transcription factor by caspases generates a carboxyl-terminal fragment that inhibits activator protein-1 transcriptional activity JKH Lee, JD Pearson, BE Maser, RJ Ingham Journal of Biological Chemistry 288 (30), 21482-21495, 2013 | 10 | 2013 |