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Andras Kotschy
Andras Kotschy
Servier Research Institute of Medicinal Chemistry
Zweryfikowany adres z servier.com
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The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
A Kotschy, Z Szlavik, J Murray, J Davidson, AL Maragno, ...
Nature 538 (7626), 477-482, 2016
11012016
Sonogashira coupling of aryl halides catalyzed by palladium on charcoal
Z Novák, A Szabó, J Répási, A Kotschy
The Journal of Organic Chemistry 68 (8), 3327-3329, 2003
2242003
Tandem Sonogashira coupling: An efficient tool for the synthesis of diarylalkynes
Z Novák, P Nemes, A Kotschy
Organic letters 6 (26), 4917-4920, 2004
1572004
Aromatic character of the benzene ring present in various topological environments in benzenoid hydrocarbons. Nonequivalence of indices of aromaticity
TM Krygowski, A Ciesielski, CW Bird, A Kotschy
Journal of chemical information and computer sciences 35 (2), 203-210, 1995
1531995
Modular synthesis of heterocyclic carbene precursors
A Paczal, AC Bényei, A Kotschy
The Journal of Organic Chemistry 71 (16), 5969-5979, 2006
1282006
The chemistry behind ADCs
V Kostova, P Désos, JB Starck, A Kotschy
Pharmaceuticals 14 (5), 442, 2021
1152021
First cross-coupling reactions on tetrazines
Z Novák, A Kotschy
Organic letters 5 (19), 3495-3497, 2003
932003
Selective nucleophilic substitutions on tetrazines
Z Novak, B Bostal, M Csekei, K Lorincz, A Kotschy
Heterocycles-Sendai Institute of Heterocyclic Chemistry 60 (12), 2653-2668, 2003
882003
Discovery of S64315, a potent and selective Mcl-1 inhibitor
Z Szlavik, M Csekei, A Paczal, ZB Szabo, S Sipos, G Radics, ...
Journal of Medicinal Chemistry 63 (22), 13762-13795, 2020
792020
Efficient copper-catalyzed trifluoromethylation of aromatic and heteroaromatic iodides: The beneficial anchoring effect of borates
Z Gonda, S Kovacs, C Wéber, T Gáti, A Mészáros, A Kotschy, Z Novák
Organic letters 16 (16), 4268-4271, 2014
792014
Development of a one-pot sequential Sonogashira coupling for the synthesis of benzofurans
M Csékei, Z Novák, A Kotschy
Tetrahedron 64 (37), 8992-8996, 2008
772008
Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans
F De Ceuninck, C Kargar, C Ilic, A Caliez, JO Rolin, T Umbdenstock, ...
British journal of pharmacology 168 (2), 339-353, 2013
732013
Structure-guided discovery of a selective Mcl-1 inhibitor with cellular activity
Z Szlávik, L Ondi, M Csékei, A Paczal, ZB Szabó, G Radics, J Murray, ...
Journal of Medicinal Chemistry 62 (15), 6913-6924, 2019
692019
The first total synthesis of Cicerfuran utilizing a one-pot synthesis of hydroxylated benzofurans
Z Novák, G Timári, A Kotschy
Tetrahedron 59 (38), 7509-7513, 2003
662003
Asymmetric synthesis in ionic liquids
A Paczal, A Kotschy
Monatshefte für Chemie-Chemical Monthly 138, 1115-1123, 2007
582007
Establishing drug discovery and identification of hit series for the anti-apoptotic proteins, Bcl-2 and Mcl-1
JB Murray, J Davidson, I Chen, B Davis, P Dokurno, CJ Graham, R Harris, ...
ACS omega 4 (5), 8892-8906, 2019
562019
Sequential and domino Sonogashira coupling: Efficient tools for the synthesis of diarylalkynes
A Nagy, Z Novák, A Kotschy
Journal of organometallic chemistry 690 (20), 4453-4461, 2005
562005
The azaphilic addition of organometallic reagents on tetrazines: scope and limitations
J Faragó, Z Novák, G Schlosser, A Csámpai, A Kotschy
Tetrahedron 60 (9), 1991-1996, 2004
512004
Ethynyl-cyclohexanol: an efficient acetylene surrogate in Sonogashira coupling
M Csékei, Z Novák, A Kotschy
Tetrahedron 64 (6), 975-982, 2008
482008
Heterocycles from transition metal catalysis: formation and functionalization
A Kotschy, G Timári
Springer Science & Business Media, 2005
482005
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