The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models A Kotschy, Z Szlavik, J Murray, J Davidson, AL Maragno, ... Nature 538 (7626), 477-482, 2016 | 1101 | 2016 |
Sonogashira coupling of aryl halides catalyzed by palladium on charcoal Z Novák, A Szabó, J Répási, A Kotschy The Journal of Organic Chemistry 68 (8), 3327-3329, 2003 | 224 | 2003 |
Tandem Sonogashira coupling: An efficient tool for the synthesis of diarylalkynes Z Novák, P Nemes, A Kotschy Organic letters 6 (26), 4917-4920, 2004 | 157 | 2004 |
Aromatic character of the benzene ring present in various topological environments in benzenoid hydrocarbons. Nonequivalence of indices of aromaticity TM Krygowski, A Ciesielski, CW Bird, A Kotschy Journal of chemical information and computer sciences 35 (2), 203-210, 1995 | 153 | 1995 |
Modular synthesis of heterocyclic carbene precursors A Paczal, AC Bényei, A Kotschy The Journal of Organic Chemistry 71 (16), 5969-5979, 2006 | 128 | 2006 |
The chemistry behind ADCs V Kostova, P Désos, JB Starck, A Kotschy Pharmaceuticals 14 (5), 442, 2021 | 115 | 2021 |
First cross-coupling reactions on tetrazines Z Novák, A Kotschy Organic letters 5 (19), 3495-3497, 2003 | 93 | 2003 |
Selective nucleophilic substitutions on tetrazines Z Novak, B Bostal, M Csekei, K Lorincz, A Kotschy Heterocycles-Sendai Institute of Heterocyclic Chemistry 60 (12), 2653-2668, 2003 | 88 | 2003 |
Discovery of S64315, a potent and selective Mcl-1 inhibitor Z Szlavik, M Csekei, A Paczal, ZB Szabo, S Sipos, G Radics, ... Journal of Medicinal Chemistry 63 (22), 13762-13795, 2020 | 79 | 2020 |
Efficient copper-catalyzed trifluoromethylation of aromatic and heteroaromatic iodides: The beneficial anchoring effect of borates Z Gonda, S Kovacs, C Wéber, T Gáti, A Mészáros, A Kotschy, Z Novák Organic letters 16 (16), 4268-4271, 2014 | 79 | 2014 |
Development of a one-pot sequential Sonogashira coupling for the synthesis of benzofurans M Csékei, Z Novák, A Kotschy Tetrahedron 64 (37), 8992-8996, 2008 | 77 | 2008 |
Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans F De Ceuninck, C Kargar, C Ilic, A Caliez, JO Rolin, T Umbdenstock, ... British journal of pharmacology 168 (2), 339-353, 2013 | 73 | 2013 |
Structure-guided discovery of a selective Mcl-1 inhibitor with cellular activity Z Szlávik, L Ondi, M Csékei, A Paczal, ZB Szabó, G Radics, J Murray, ... Journal of Medicinal Chemistry 62 (15), 6913-6924, 2019 | 69 | 2019 |
The first total synthesis of Cicerfuran utilizing a one-pot synthesis of hydroxylated benzofurans Z Novák, G Timári, A Kotschy Tetrahedron 59 (38), 7509-7513, 2003 | 66 | 2003 |
Asymmetric synthesis in ionic liquids A Paczal, A Kotschy Monatshefte für Chemie-Chemical Monthly 138, 1115-1123, 2007 | 58 | 2007 |
Establishing drug discovery and identification of hit series for the anti-apoptotic proteins, Bcl-2 and Mcl-1 JB Murray, J Davidson, I Chen, B Davis, P Dokurno, CJ Graham, R Harris, ... ACS omega 4 (5), 8892-8906, 2019 | 56 | 2019 |
Sequential and domino Sonogashira coupling: Efficient tools for the synthesis of diarylalkynes A Nagy, Z Novák, A Kotschy Journal of organometallic chemistry 690 (20), 4453-4461, 2005 | 56 | 2005 |
The azaphilic addition of organometallic reagents on tetrazines: scope and limitations J Faragó, Z Novák, G Schlosser, A Csámpai, A Kotschy Tetrahedron 60 (9), 1991-1996, 2004 | 51 | 2004 |
Ethynyl-cyclohexanol: an efficient acetylene surrogate in Sonogashira coupling M Csékei, Z Novák, A Kotschy Tetrahedron 64 (6), 975-982, 2008 | 48 | 2008 |
Heterocycles from transition metal catalysis: formation and functionalization A Kotschy, G Timári Springer Science & Business Media, 2005 | 48 | 2005 |