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Rowena Martin
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Functional profiling of a Plasmodium genome reveals an abundance of essential genes
E Bushell, AR Gomes, T Sanderson, B Anar, G Girling, C Herd, T Metcalf, ...
Cell 170 (2), 260-272. e8, 2017
5692017
Chloroquine transport via the malaria parasite’s chloroquine resistance transporter
RE Martin, RV Marchetti, AI Cowan, SM Howitt, S Bröer, K Kirk
science 325 (5948), 1680-1682, 2009
4172009
Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies
MI Veiga, SK Dhingra, PP Henrich, J Straimer, N Gnädig, AC Uhlemann, ...
Nature communications 7 (1), 11553, 2016
3062016
Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance
PG Bray, RE Martin, L Tilley, SA Ward, K Kirk, DA Fidock
Molecular microbiology 56 (2), 323-333, 2005
3022005
The malaria parasite's chloroquine resistance transporter is a member of the drug/metabolite transporter superfamily
RE Martin, K Kirk
Molecular biology and evolution 21 (10), 1938-1949, 2004
2922004
The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum
RE Martin, RI Henry, JL Abbey, JD Clements, K Kirk
Genome biology 6, 1-22, 2005
2252005
Transport of the essential nutrient isoleucine in human erythrocytes infected with the malaria parasite Plasmodium falciparum
RE Martin, K Kirk
Blood 109 (5), 2217-2224, 2007
1672007
Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite
KJ Saliba, RE Martin, A Bröer, RI Henry, C Siobhan McCarthy, MJ Downie, ...
Nature 443 (7111), 582-585, 2006
1222006
Membrane transport proteins of the malaria parasite
RE Martin, H Ginsburg, K Kirk
Molecular microbiology 74 (3), 519-528, 2009
1052009
Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics
RL Summers, MN Nash, RE Martin
Cellular and Molecular Life Sciences 69, 1967-1995, 2012
1012012
Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite’s food vacuole and alter drug sensitivities
S Pulcini, HM Staines, AH Lee, SH Shafik, G Bouyer, CM Moore, ...
Scientific reports 5 (1), 14552, 2015
982015
The natural function of the malaria parasite’s chloroquine resistance transporter
SH Shafik, SA Cobbold, K Barkat, SN Richards, NS Lancaster, M Llinás, ...
Nature communications 11 (1), 3922, 2020
862020
A lactate and formate transporter in the intraerythrocytic malaria parasite, Plasmodium falciparum
RV Marchetti, AM Lehane, SH Shafik, M Winterberg, RE Martin, K Kirk
Nature communications 6 (1), 6721, 2015
832015
Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant Plasmodium falciparum and inhibit chloroquine transport via the P. falciparum …
VK Zishiri, MC Joshi, R Hunter, K Chibale, PJ Smith, RL Summers, ...
Journal of medicinal chemistry 54 (19), 6956-6968, 2011
822011
Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite’s chloroquine resistance transporter
RL Summers, A Dave, TJ Dolstra, S Bellanca, RV Marchetti, MN Nash, ...
Proceedings of the National Academy of Sciences 111 (17), E1759-E1767, 2014
812014
Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents
S Gemma, C Camodeca, M Brindisi, S Brogi, G Kukreja, S Kunjir, ...
Journal of medicinal chemistry 55 (23), 10387-10404, 2012
732012
The transportome of the malaria parasite
RE Martin
Biological Reviews 95 (2), 305-332, 2020
622020
The malaria parasite's lactate transporter PfFNT is the target of antiplasmodial compounds identified in whole cell phenotypic screens
SV Hapuarachchi, SA Cobbold, SH Shafik, ASM Dennis, MJ McConville, ...
PLoS pathogens 13 (2), e1006180, 2017
592017
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure–activity relationships, in vivo studies, and preliminary toxicity profiling
S Gemma, C Camodeca, S Sanna Coccone, BP Joshi, M Bernetti, ...
Journal of medicinal chemistry 55 (15), 6948-6967, 2012
562012
Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites
S Bellanca, RL Summers, M Meyrath, A Dave, MN Nash, M Dittmer, ...
Journal of Biological Chemistry 289 (52), 36336-36351, 2014
522014
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