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Mengyang Fan
Mengyang Fan
Postdoctoral Research Fellow, Dana Farber Cancer Institute, Harvard Medical School
Zweryfikowany adres z dfci.harvard.edu
Tytuł
Cytowane przez
Cytowane przez
Rok
Treatment-induced tumor dormancy through YAP-mediated transcriptional reprogramming of the apoptotic pathway
KJ Kurppa, Y Liu, C To, T Zhang, M Fan, A Vajdi, EH Knelson, Y Xie, ...
Cancer cell 37 (1), 104-122. e12, 2020
4072020
CuI/oxalic diamide catalyzed coupling reaction of (hetero) aryl chlorides and amines
W Zhou, M Fan, J Yin, Y Jiang, D Ma
Journal of the American Chemical Society 137 (37), 11942-11945, 2015
2372015
Palladium-catalyzed direct functionalization of 2-aminobutanoic acid derivatives: application of a convenient and versatile auxiliary.
M Fan, D Ma
Angewandte Chemie International Edition 52 (46), 2013
1802013
Assembly of primary (hetero) arylamines via CuI/oxalic diamide-catalyzed coupling of aryl chlorides and ammonia
M Fan, W Zhou, Y Jiang, D Ma
Organic Letters 17 (23), 5934-5937, 2015
1452015
CuI/Oxalamide catalyzed couplings of (Hetero) aryl chlorides and phenols for diaryl ether formation
M Fan, W Zhou, Y Jiang, D Ma
Angewandte Chemie International Edition 55 (21), 6211-6215, 2016
1332016
Copper-catalyzed diaryl ether formation from (hetero) aryl halides at low catalytic loadings
Y Zhai, X Chen, W Zhou, M Fan, Y Lai, D Ma
The Journal of Organic Chemistry 82 (9), 4964-4969, 2017
612017
Assembly of Indoline-2-carboxylate-Embodied Dipeptides via Pd-Catalyzed C(sp2)–H Bond Direct Functionalization
YP He, C Zhang, M Fan, Z Wu, D Ma
Organic Letters 17 (3), 496-499, 2015
562015
Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling
M Fan, W Lu, J Che, NP Kwiatkowski, Y Gao, HS Seo, SB Ficarro, ...
Elife 11, e78810, 2022
462022
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor
N Darabedian, W Ji, M Fan, S Lin, HS Seo, EV Vinogradova, TM Yaron, ...
Nature chemical biology 19 (7), 815-824, 2023
342023
Total Synthesis of Lapidilectine B Enabled by Manganese (III)‐Mediated Oxidative Cyclization of Indoles
Y Gao, M Fan, Q Geng, D Ma
Chemistry–A European Journal 24 (25), 6547-6550, 2018
302018
Structure-based design of Y-shaped covalent TEAD inhibitors
W Lu, M Fan, W Ji, J Tse, I You, SB Ficarro, I Tavares, J Che, AY Kim, ...
Journal of medicinal chemistry 66 (7), 4617-4632, 2023
162023
Spatiotemporal quantification of HER2-targeting antibody–drug conjugate bystander activity and enhancement of solid tumor penetration
Q Wei, T Yang, J Zhu, Z Zhang, L Yang, Y Zhang, C Hu, J Chen, J Wang, ...
Clinical Cancer Research 30 (5), 984-997, 2024
102024
Discovery of novel macrocyclic derivatives as potent and selective cyclin-dependent kinase 2 inhibitors
P Niu, Y Tao, Q Meng, Y Huang, S Li, K Ding, D Ma, Z Ye, M Fan
Bioorganic & Medicinal Chemistry 104, 117711, 2024
62024
Amino pyrimidine compounds useful as SSAO inhibitors
M Fan, L Qin, Y Wei, G Zhou, J Zhou
US Patent 10,278,970, 2019
62019
Discovery and optimization of thieno [3, 2-d] pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
H Zhang, G Lin, S Jia, Y Zhang, J Wu, Y Tao, W Huang, M Song, K Ding, ...
European Journal of Medicinal Chemistry 263, 115955, 2024
42024
Transcriptional enhanced associate domain (tead) transcription factor inhibitors and uses thereof
NS Gray, T Zhang, Y Liu, M Fan, Y Gao
US Patent App. 17/285,791, 2022
42022
Design, synthesis and evaluation of thieno [3, 2-d] pyrimidine derivatives as novel potent CDK7 inhibitors
H Zhang, G Lin, S Jia, J Wu, Y Zhang, Y Tao, W Huang, M Song, K Ding, ...
Bioorganic Chemistry 148, 107456, 2024
32024
Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors
P Niu, Y Tao, G Lin, H Xu, Q Meng, K Yang, W Huang, M Song, K Ding, ...
Journal of Medicinal Chemistry 67 (8), 6099-6118, 2024
32024
Blocker-SELEX: a structure-guided strategy for developing inhibitory aptamers disrupting undruggable transcription factor interactions
T Li, X Liu, H Qian, S Zhang, Y Hou, Y Zhang, G Luo, X Zhu, Y Tao, M Fan, ...
Nature Communications 15 (1), 6751, 2024
22024
Discovery and optimization of (2-naphthylthio) acetic acid derivative as selective Bfl-1 inhibitor
P Niu, H Xu, M Fan
Bioorganic & Medicinal Chemistry Letters 101, 129658, 2024
22024
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