Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca2+/Calmodulin-Dependent Protein Kinase II δ Signaling in … T Suetomi, A Willeford, CS Brand, Y Cho, RS Ross, S Miyamoto, ... Circulation 138 (22), 2530-2544, 2018 | 267 | 2018 |
Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the … S Kobayashi, M Yano, T Suetomi, M Ono, H Tateishi, M Mochizuki, X Xu, ... Journal of the American College of Cardiology 53 (21), 1993-2005, 2009 | 219 | 2009 |
Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor H Uchinoumi, M Yano, T Suetomi, M Ono, X Xu, H Tateishi, T Oda, ... Circulation research 106 (8), 1413-1424, 2010 | 188 | 2010 |
Dantrolene, a therapeutic agent for malignant hyperthermia, inhibits catecholaminergic polymorphic ventricular tachycardia in a RyR2R2474S/+ knock-in mouse model S Kobayashi, M Yano, H Uchinoumi, T Suetomi, T Susa, M Ono, X Xu, ... Circulation Journal 74 (12), 2579-2584, 2010 | 147 | 2010 |
CaMKIIδ-mediated inflammatory gene expression and inflammasome activation in cardiomyocytes initiate inflammation and induce fibrosis A Willeford, T Suetomi, A Nickle, HM Hoffman, S Miyamoto, JH Brown JCI insight 3 (12), e97054, 2018 | 122 | 2018 |
Defective domain–domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts H Tateishi, M Yano, M Mochizuki, T Suetomi, M Ono, X Xu, H Uchinoumi, ... Cardiovascular research 81 (3), 536-545, 2009 | 108 | 2009 |
Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca2+ release in heart failure M Ono, M Yano, A Hino, T Suetomi, X Xu, T Susa, H Uchinoumi, ... Cardiovascular research 87 (4), 609-617, 2010 | 107 | 2010 |
Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction X Xu, M Yano, H Uchinoumi, A Hino, T Suetomi, M Ono, H Tateishi, T Oda, ... Biochemical and biophysical research communications 394 (3), 660-666, 2010 | 106 | 2010 |
Inflammation in nonischemic heart disease: initiation by cardiomyocyte CaMKII and NLRP3 inflammasome signaling T Suetomi, S Miyamoto, JH Brown American Journal of Physiology-Heart and Circulatory Physiology 317 (5 …, 2019 | 87 | 2019 |
CaMKIIδ subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-κB and TNF-α CBB Gray, T Suetomi, S Xiang, S Mishra, EA Blackwood, CC Glembotski, ... Journal of molecular and cellular cardiology 103, 48-55, 2017 | 79 | 2017 |
Mutation-Linked Defective Interdomain Interactions Within Ryanodine Receptor Cause Aberrant Ca2+ Release Leading to Catecholaminergic Polymorphic … T Suetomi, M Yano, H Uchinoumi, M Fukuda, A Hino, M Ono, X Xu, ... Circulation 124 (6), 682-694, 2011 | 73 | 2011 |
Three-dimensional optical coherence tomography assessment of coronary wire re-crossing position during bifurcation stenting T Okamura, J Yamada, T Nao, T Suetomi, T Maeda, K Shiraishi, T Miura, ... EuroIntervention 7 (7), 886-887, 2011 | 38 | 2011 |
Enhanced binding of calmodulin to the ryanodine receptor corrects contractile dysfunction in failing hearts A Hino, M Yano, T Kato, M Fukuda, T Suetomi, M Ono, W Murakami, ... Cardiovascular research 96 (3), 433-443, 2012 | 35 | 2012 |
A low-dose β1-blocker in combination with milrinone improves intracellular Ca2+ handling in failing cardiomyocytes by inhibition of milrinone-induced diastolic Ca2+ leakage … S Kobayashi, T Susa, H Ishiguchi, T Myoren, W Murakami, T Kato, ... PLoS One 10 (1), e0114314, 2015 | 27 | 2015 |
Stabilization of RyR2 maintains right ventricular function, reduces the development of ventricular arrhythmias, and improves prognosis in pulmonary hypertension S Tanaka, T Yamamoto, M Mikawa, J Nawata, S Fujii, Y Nakamura, T Kato, ... Heart Rhythm 19 (6), 986-997, 2022 | 13 | 2022 |
RyR2-targeting therapy prevents left ventricular remodeling and ventricular tachycardia in post-infarction heart failure S Fujii, S Kobayashi, Y Chang, J Nawata, R Yoshitomi, S Tanaka, ... Journal of Molecular and Cellular Cardiology 178, 36-50, 2023 | 11 | 2023 |
Differences of side branch jailing between left main–left anterior descending artery stenting and left main–left circumflex artery stenting with Nobori biolimus-eluting stent F Nakao, T Okamura, T Suetomi, J Yamada, T Nakamura, T Ueda, T Oda, ... Heart and vessels 31, 1895-1903, 2016 | 8 | 2016 |
Stabilizing cardiac ryanodine receptor with dantrolene treatment prevents left ventricular remodeling in pressure-overloaded heart failure mice Y Yano, S Kobayashi, T Uchida, Y Chang, J Nawata, S Fujii, Y Nakamura, ... Biochemical and Biophysical Research Communications 642, 175-184, 2023 | 6 | 2023 |
A Marked increase in myocardial oxidative stress associated with sympathetic hyperactivity is related to transient myocardial dysfunction in patients with takotsubo cardiomyopathy T Nanno, S Kobayashi, S Oda, H Ishiguchi, T Myoren, Y Miyazaki, ... Circulation 132 (suppl_3), A14124-A14124, 2015 | 6 | 2015 |
Serial changes in the quantitative flow ratio in patients with intermediate residual stenosis after percutaneous coronary intervention H Takenaka, T Okamura, Y Miyazaki, T Fujimura, A Ono, T Nakamura, ... Heart and Vessels 37 (3), 363-373, 2022 | 5 | 2022 |