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| EGF receptor is required for KRAS-induced pancreatic tumorigenesis CM Ardito, BM Grüner, KK Takeuchi, C Lubeseder-Martellato, ... Cancer cell 22 (3), 304-317, 2012 | 567 | 2012 |
| Pancreatic cancer: Advances and challenges CJ Halbrook, CA Lyssiotis, MP di Magliano, A Maitra Cell 186 (8), 1729-1754, 2023 | 550 | 2023 |
| Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ... Cell metabolism 29 (6), 1390-1399. e6, 2019 | 392 | 2019 |
| Employing metabolism to improve the diagnosis and treatment of pancreatic cancer CJ Halbrook, CA Lyssiotis Cancer cell 31 (1), 5-19, 2017 | 391 | 2017 |
| Regulatory T-cell depletion alters the tumor microenvironment and accelerates pancreatic carcinogenesis Y Zhang, J Lazarus, NG Steele, W Yan, HJ Lee, ZC Nwosu, CJ Halbrook, ... Cancer discovery 10 (3), 422-439, 2020 | 336 | 2020 |
| Inhibition of hedgehog signaling alters fibroblast composition in pancreatic cancer NG Steele, G Biffi, SB Kemp, Y Zhang, D Drouillard, LJ Syu, Y Hao, ... Clinical Cancer Research 27 (7), 2023-2037, 2021 | 226 | 2021 |
| Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth AS Krall, PJ Mullen, F Surjono, M Momcilovic, EW Schmid, CJ Halbrook, ... Cell metabolism 33 (5), 1013-1026. e6, 2021 | 211 | 2021 |
| GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ... Nature communications 12 (1), 4860, 2021 | 191 | 2021 |
| Purine metabolism regulates DNA repair and therapy resistance in glioblastoma W Zhou, Y Yao, AJ Scott, K Wilder-Romans, JJ Dresser, CK Werner, ... Nature communications 11 (1), 3811, 2020 | 170 | 2020 |
| Endoplasmic reticulum–associated degradation regulates mitochondrial dynamics in brown adipocytes Z Zhou, M Torres, H Sha, CJ Halbrook, F Van den Bergh, RB Reinert, ... Science 368 (6486), 54-60, 2020 | 142 | 2020 |
| PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice CYC Wu, ES Carpenter, KK Takeuchi, CJ Halbrook, LV Peverley, H Bien, ... Gastroenterology 147 (6), 1405-1416. e7, 2014 | 130 | 2014 |
| Identification and manipulation of biliary metaplasia in pancreatic tumors KE DelGiorno, JC Hall, KK Takeuchi, FC Pan, CJ Halbrook, ... Gastroenterology 146 (1), 233-244. e5, 2014 | 124 | 2014 |
| PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance N Roy, KK Takeuchi, JM Ruggeri, P Bailey, D Chang, J Li, L Leonhardt, ... Genes & development 30 (24), 2669-2683, 2016 | 107 | 2016 |
| Hyaluronic acid fuels pancreatic cancer cell growth PK Kim, CJ Halbrook, SA Kerk, M Radyk, S Wisner, DM Kremer, ... Elife 10, e62645, 2021 | 88 | 2021 |
| Uridine-derived ribose fuels glucose-restricted pancreatic cancer ZC Nwosu, MH Ward, P Sajjakulnukit, P Poudel, C Ragulan, S Kasperek, ... Nature 618 (7963), 151-158, 2023 | 81 | 2023 |
| Interleukin 22 signaling regulates acinar cell plasticity to promote pancreatic tumor development in mice MP Lanfranca, Y Zhang, A Girgis, S Kasselman, J Lazarus, I Kryczek, ... Gastroenterology 158 (5), 1417-1432. e11, 2020 | 80 | 2020 |
| Arginase 1 is a key driver of immune suppression in pancreatic cancer RE Menjivar, ZC Nwosu, W Du, KL Donahue, HS Hong, C Espinoza, ... Elife 12, e80721, 2023 | 74 | 2023 |
| Barriers and opportunities for gemcitabine in pancreatic cancer therapy AK Beutel, CJ Halbrook American Journal of Physiology-Cell Physiology 324 (2), C540-C552, 2023 | 63 | 2023 |
| Mitogen-activated protein kinase kinase activity maintains acinar-to-ductal metaplasia and is required for organ regeneration in pancreatitis CJ Halbrook, HJ Wen, JM Ruggeri, KK Takeuchi, Y Zhang, ... Cellular and molecular gastroenterology and hepatology 3 (1), 99-118, 2017 | 63 | 2017 |