Chk1 is an essential kinase that is regulated by Atr and required for the G2/M DNA damage checkpoint Q Liu, S Guntuku, XS Cui, S Matsuoka, D Cortez, K Tamai, G Luo, ... Genes & development 14 (12), 1448-1459, 2000 | 2211 | 2000 |
ATR: an essential regulator of genome integrity KA Cimprich, D Cortez Nature reviews Molecular cell biology 9 (8), 616-627, 2008 | 2207 | 2008 |
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures Y Wang, D Cortez, P Yazdi, N Neff, SJ Elledge, J Qin Genes & development 14 (8), 927-939, 2000 | 1637 | 2000 |
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks D Cortez, Y Wang, J Qin, SJ Elledge Science 286 (5442), 1162-1166, 1999 | 1409 | 1999 |
ATR and ATRIP: partners in checkpoint signaling D Cortez, S Guntuku, J Qin, SJ Elledge Science 294 (5547), 1713-1716, 2001 | 1289 | 2001 |
Replication fork stability confers chemoresistance in BRCA-deficient cells A Ray Chaudhuri, E Callen, X Ding, E Gogola, AA Duarte, JE Lee, ... Nature 535 (7612), 382-387, 2016 | 927 | 2016 |
The essential kinase ATR: ensuring faithful duplication of a challenging genome JC Saldivar, D Cortez, KA Cimprich Nature reviews Molecular cell biology 18 (10), 622-636, 2017 | 845 | 2017 |
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress RS Tibbetts, D Cortez, KM Brumbaugh, R Scully, D Livingston, SJ Elledge, ... Genes & development 14 (23), 2989-3002, 2000 | 700 | 2000 |
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin L Zou, D Cortez, SJ Elledge Genes & development 16 (2), 198-208, 2002 | 647 | 2002 |
A requirement for NF-κB activation in Bcr–Abl-mediated transformation JY Reuther, GW Reuther, D Cortez, AM Pendergast, AS Baldwin Genes & development 12 (7), 968-981, 1998 | 527 | 1998 |
Analysis of protein dynamics at active, stalled, and collapsed replication forks BM Sirbu, FB Couch, JT Feigerle, S Bhaskara, SW Hiebert, D Cortez Genes & development 25 (12), 1320-1327, 2011 | 499 | 2011 |
ATR phosphorylates SMARCAL1 to prevent replication fork collapse FB Couch, CE Bansbach, R Driscoll, JW Luzwick, GG Glick, R Bétous, ... Genes & development 27 (14), 1610-1623, 2013 | 473 | 2013 |
Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control S Bhaskara, BJ Chyla, JM Amann, SK Knutson, D Cortez, ZW Sun, ... Molecular cell 30 (1), 61-72, 2008 | 456 | 2008 |
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain DA Mordes, GG Glick, R Zhao, D Cortez Genes & development 22 (11), 1478-1489, 2008 | 452 | 2008 |
Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases D Cortez, G Glick, SJ Elledge Proceedings of the National Academy of Sciences 101 (27), 10078-10083, 2004 | 448 | 2004 |
ATR signalling: more than meeting at the fork EA Nam, D Cortez Biochemical Journal 436 (3), 527-536, 2011 | 416 | 2011 |
The replication checkpoint prevents two types of fork collapse without regulating replisome stability H Dungrawala, KL Rose, KP Bhat, KN Mohni, GG Glick, FB Couch, ... Molecular cell 59 (6), 998-1010, 2015 | 413 | 2015 |
Rapid activation of ATR by ionizing radiation requires ATM and Mre11 JS Myers, D Cortez Journal of Biological Chemistry 281 (14), 9346-9350, 2006 | 411 | 2006 |
Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis D Cortez, L Kadlec, AM Pendergast Molecular and cellular biology 15 (10), 5531-5541, 1995 | 402 | 1995 |
Common mechanisms of PIKK regulation CA Lovejoy, D Cortez DNA repair 8 (9), 1004-1008, 2009 | 383 | 2009 |