| The spliceosome is a therapeutic vulnerability in MYC-driven cancer TYT Hsu, LM Simon, NJ Neill, R Marcotte, A Sayad, CS Bland, ... Nature 525 (7569), 384-388, 2015 | 505 | 2015 |
| Functional genomic landscape of human breast cancer drivers, vulnerabilities, and resistance R Marcotte, A Sayad, KR Brown, F Sanchez-Garcia, J Reimand, M Haider, ... Cell 164 (1), 293-309, 2016 | 481 | 2016 |
| Essential gene profiles in breast, pancreatic, and ovarian cancer cells R Marcotte, KR Brown, F Suarez, A Sayad, K Karamboulas, ... Cancer discovery 2 (2), 172-189, 2012 | 388 | 2012 |
| The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells J Petschnigg, B Groisman, M Kotlyar, M Taipale, Y Zheng, CF Kurat, ... Nature methods 11 (5), 585-592, 2014 | 204 | 2014 |
| A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities FJ Vizeacoumar, R Arnold, FS Vizeacoumar, M Chandrashekhar, ... Molecular systems biology 9 (1), 696, 2013 | 116 | 2013 |
| Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer CA Chang, J Jen, S Jiang, A Sayad, AS Mer, KR Brown, AML Nixon, ... Cancer discovery 12 (4), 1022-1045, 2022 | 79 | 2022 |
| High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation HL MacGregor, A Sayad, A Elia, BX Wang, SR Katz, PA Shaw, BA Clarke, ... Journal for ImmunoTherapy of Cancer 7, 1-17, 2019 | 68 | 2019 |
| Coenzyme A fuels T cell anti-tumor immunity MS Paul, SD Saibil, SJ Han, K Israni-Winger, SC Lien, RC Laister, ... Cell metabolism 33 (12), 2415-2427. e6, 2021 | 65 | 2021 |
| COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines JLY Koh, KR Brown, A Sayad, D Kasimer, T Ketela, J Moffat Nucleic acids research 40 (D1), D957-D963, 2012 | 63 | 2012 |
| Essential gene profiles in breast, pancreatic, and ovarian cancer cells. Cancer Discov. 2012; 2: 172–189. doi: 10.1158/2159-8290 R Marcotte, KR Brown, F Suarez, A Sayad, K Karamboulas, ... CD-11-0224.[Europe PMC free article][Abstract][CrossRef][Academic Search], 2012 | 59 | 2012 |
| SHP2 is required for BCR-ABL1-induced hematologic neoplasia S Gu, A Sayad, G Chan, W Yang, Z Lu, C Virtanen, RA Van Etten, ... Leukemia 32 (1), 203-213, 2018 | 46 | 2018 |
| IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function M St. Paul, SD Saibil, SC Lien, SJ Han, A Sayad, DT Mulder, ... Cancer immunology research 8 (3), 321-333, 2020 | 43 | 2020 |
| Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer HL MacGregor, C Garcia-Batres, A Sayad, A Elia, HK Berman, A Toker, ... Oncoimmunology 8 (12), e1665460, 2019 | 34 | 2019 |
| Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1 S Gu, WW Chan, G Mohi, J Rosenbaum, A Sayad, Z Lu, C Virtanen, S Li, ... Blood, The Journal of the American Society of Hematology 127 (14), 1803-1813, 2016 | 30 | 2016 |
| A genomically characterized collection of high-grade serous ovarian cancer xenografts for preclinical testing P Cybulska, JM Stewart, A Sayad, C Virtanen, PA Shaw, B Clarke, ... The American Journal of Pathology 188 (5), 1120-1131, 2018 | 29 | 2018 |
| Computational modeling of ovarian cancer dynamics suggests optimal strategies for therapy and screening S Gu, S Lheureux, A Sayad, P Cybulska, L Hogen, I Vyarvelska, D Tu, ... Proceedings of the National Academy of Sciences 118 (25), e2026663118, 2021 | 18 | 2021 |
| Overproduction of IFNγ by Cbl-b–Deficient CD8+ T Cells Provides Resistance against Regulatory T Cells and Induces Potent Antitumor Immunity SJ Han, ZQ Liu, DC Chung, MS Paul, CR Garcia-Batres, A Sayad, ... Cancer Immunology Research 10 (4), 437-452, 2022 | 11 | 2022 |
| Proteomic dynamics of breast cancer cell lines identifies potential therapeutic protein targets R Sun, W Ge, Y Zhu, A Sayad, A Luna, M Lyu, S Liang, L Tobalina, ... Molecular & Cellular Proteomics 22 (8), 2023 | 10 | 2023 |
| Integrated genomic, transcriptomic, and RNA-interference analysis of genes in somatic copy number gains in pancreatic ductal adenocarcinoma N Samuel, A Sayad, G Wilson, M Lemire, KR Brown, L Muthuswamy, ... Pancreas 42 (6), 1016-1026, 2013 | 8 | 2013 |
| Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire DG Millar, SYC Yang, A Sayad, Q Zhao, LT Nguyen, K Warner, ... Cancer Immunology, Immunotherapy 72 (7), 2375-2392, 2023 | 7 | 2023 |
Jason MoffatSenior Scientist & Program Head, Genetics & Genome Biology, Sickkids Hospital; Professor, UofTZweryfikowany adres z utoronto.ca
