| Multiplexed quantitative proteomic analysis of HEK293 provides insights into molecular changes associated with the cell density effect, transient transfection, and virus-like … J Lavado-García, I Jorge, L Cervera, J Vázquez, F Gòdia Journal of Proteome Research 19 (3), 1085-1099, 2020 | 40 | 2020 |
| The cell density effect in animal cell-based bioprocessing: Questions, insights and perspectives J Lavado-García, P Pérez-Rubio, L Cervera, F Gòdia Biotechnology advances 60, 108017, 2022 | 29 | 2022 |
| Characterization of HIV‐1 virus‐like particles and determination of Gag stoichiometry for different production platforms J Lavado‐García, I Jorge, A Boix‐Besora, J Vázquez, F Gòdia, L Cervera Biotechnology and bioengineering 118 (7), 2660-2675, 2021 | 29 | 2021 |
| Optimization, production, purification and characterization of HIV-1 GAG-based virus-like particles functionalized with SARS-CoV-2 A Boix-Besora, E Lorenzo, J Lavado-García, F Gòdia, L Cervera Vaccines 10 (2), 250, 2022 | 27 | 2022 |
| An alternative perfusion approach for the intensification of virus-like particle production in HEK293 cultures J Lavado-García, L Cervera, F Gòdia Frontiers in Bioengineering and Biotechnology 8, 617, 2020 | 26 | 2020 |
| Molecular characterization of the coproduced extracellular vesicles in HEK293 during virus-like particle production J Lavado-Garcia, I Gonzalez-Dominguez, L Cervera, I Jorge, J Vazquez, ... Journal of proteome research 19 (11), 4516-4532, 2020 | 22 | 2020 |
| Metabolic engineering of HEK293 cells to improve transient transfection and cell budding of HIV‐1 virus‐like particles J Lavado‐García, A Díaz‐Maneh, N Canal‐Paulí, P Pérez‐Rubio, F Gòdia, ... Biotechnology and Bioengineering 118 (4), 1630-1644, 2021 | 20 | 2021 |
| Micrometric DNA/PEI polyplexes correlate with higher transient gene expression yields in HEK 293 cells I González-Domínguez, E Puente-Massaguer, J Lavado-García, ... New Biotechnology 68, 87-96, 2022 | 15 | 2022 |
| Expression of spidroin proteins in the silk glands of golden orb‐weaver spiders I Jorge, V Ruiz, J Lavado‐García, J Vázquez, C Hayashi, FJ Rojo, ... Journal of Experimental Zoology Part B: Molecular and Developmental …, 2022 | 11 | 2022 |
| Differential N‐ and O‐glycosylation signatures of HIV‐1 Gag virus‐like particles and coproduced extracellular vesicles J Lavado‐García, T Zhang, L Cervera, F Gòdia, M Wuhrer Biotechnology and Bioengineering 119 (5), 1207-1221, 2022 | 11 | 2022 |
| An alternative perfusion approach for the intensification of virus-like particle production in HEK293 cultures. Front Bioeng Biotechnol 8: 617 J Lavado-García, L Cervera, F Gòdia | 8 | 2020 |
| Extracellular vesicle depletion and UGCG overexpression mitigate the cell density effect in HEK293 cell culture transfection P Pérez-Rubio, J Lavado-García, L Bosch-Molist, EL Romero, L Cervera, ... Molecular Therapy Methods & Clinical Development 32 (1), 2024 | 7 | 2024 |
| Unravelling the essential elements for recombinant adeno-associated virus (rAAV) production in animal cell-based platforms D Catalán-Tatjer, K Tzimou, LK Nielsen, J Lavado-García Biotechnology Advances, 108370, 2024 | 4 | 2024 |
| Unlocking DOE potential by selecting the most appropriate design for rAAV optimization K Tzimou, D Catalán-Tatjer, LK Nielsen, J Lavado-García Molecular Therapy Methods & Clinical Development 32 (4), 2024 | 2 | 2024 |
| Internalization of PEI-based complexes in transient transfection of HEK293 cells is triggered by coalescence of membrane heparan sulfate proteoglycans like Glypican-4 P Pérez-Rubio, M Vendrell-Flotats, EL Romero, K Enemark-Rasmussen, ... Biomedicine & Pharmacotherapy 176, 116893, 2024 | 2 | 2024 |
| Targeted knockdown of ATM, ATR, and PDEδ increases Gag HIV-1 VLP production in HEK293 cells A Díaz-Maneh, P Pérez-Rubio, CR Granes, L Bosch-Molist, ... Applied Microbiology and Biotechnology 109 (1), 1, 2025 | | 2025 |
| Systematic insights into cell density-dependent transcriptional responses upon medium replacements P Pérez-Rubio, EL Romero, L Cervera, F Gòdia, LK Nielsen, ... Biomedicine & Pharmacotherapy 181, 117640, 2024 | | 2024 |
| Evaluating apoptotic gene efficiency for CHO culture performance using targeted integration D Catalán-Tatjer, SK Ganesan, I Martínez-Monge, LM Grav, ... bioRxiv, 2024.05. 29.596411, 2024 | | 2024 |
| Optimizing triple transfection for enhanced rAAV production: A Response Surface Methodology approach J Lavado García, D Catalán-Tatjer, K Tzimou, LK Nielsen | | 2024 |
| An efficient plasmid ratio optimization for rAAV production can be achieved using a mixture design K Tzimou, D Catalán-Tatjer, J Lavado-García, L Keld Nielsen | | 2024 |