APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A L Wong, FS Vizeacoumar, FJ Vizeacoumar, L Chelico Nucleic Acids Research 49 (1), 322-339, 2021 | 22 | 2021 |
Single-nucleotide polymorphism of the DNA cytosine deaminase APOBEC3H haplotype I leads to enzyme destabilization and correlates with lung cancer MA Hix, L Wong, B Flath, L Chelico, GA Cisneros NAR cancer 2 (3), zcaa023, 2020 | 15 | 2020 |
RNA-mediated dimerization of the human deoxycytidine deaminase APOBEC3H influences enzyme activity and interaction with nucleic acids Y Feng, L Wong, M Morse, I Rouzina, MC Williams, L Chelico Journal of molecular biology 430 (24), 4891-4907, 2018 | 14 | 2018 |
Competition for DNA binding between the genome protector replication protein A and the genome modifying APOBEC3 single-stranded DNA deaminases L Wong, A Sami, L Chelico Nucleic Acids Research 50 (21), 12039-12057, 2022 | 12 | 2022 |
Enhancing the throughput and multiplexing capabilities of next generation sequencing for efficient implementation of pooled shRNA and CRISPR screens MF Islam, A Watanabe, L Wong, C Lazarou, FS Vizeacoumar, ... Scientific Reports 7 (1), 1040, 2017 | 3 | 2017 |
Similar deamination activities but different phenotypic outcomes induced by APOBEC3 enzymes in breast epithelial cells M Granadillo Rodríguez, L Wong, L Chelico Frontiers in Genome Editing 5, 1196697, 2023 | 1 | 2023 |
Induced mutagenesis by the DNA cytosine deaminase APOBEC3H Haplotype I protects against lung cancer MA Hix, L Wong, B Flath, L Chelico, GA Cisneros bioRxiv, 2020.02. 28.970509, 2020 | 1 | 2020 |