Mechanistic landscape of membrane-permeabilizing peptides S Guha, J Ghimire, E Wu, WC Wimley Chemical reviews 119 (9), 6040-6085, 2019 | 235 | 2019 |
Applications and evolution of melittin, the quintessential membrane active peptide S Guha, RP Ferrie, J Ghimire, CR Ventura, E Wu, L Sun, SY Kim, ... Biochemical pharmacology 193, 114769, 2021 | 111 | 2021 |
Synthetic molecular evolution of host cell-compatible, antimicrobial peptides effective against drug-resistant, biofilm-forming bacteria CG Starr, J Ghimire, S Guha, JP Hoffmann, Y Wang, L Sun, ... Proceedings of the National Academy of Sciences 117 (15), 8437-8448, 2020 | 68 | 2020 |
Broad-spectrum antiviral entry inhibition by interfacially active peptides AR Hoffmann, S Guha, E Wu, J Ghimire, Y Wang, J He, RF Garry, ... Journal of Virology 94 (23), 10.1128/jvi. 01682-20, 2020 | 31 | 2020 |
Integrated design of a membrane‐lytic peptide‐based intravenous nanotherapeutic suppresses triple‐negative breast cancer CH Chen, YH Liu, A Eskandari, J Ghimire, LCW Lin, ZS Fang, WC Wimley, ... Advanced Science 9 (13), 2105506, 2022 | 15 | 2022 |
Ebola virus delta peptide is an enterotoxin LI Melnik, S Guha, J Ghimire, AR Smither, BJ Beddingfield, AR Hoffmann, ... Cell Reports 38 (1), 2022 | 11 | 2022 |
The Remarkable Innate Resistance of Burkholderia bacteria to Cationic Antimicrobial Peptides: Insights into the Mechanism of AMP Resistance J Ghimire, S Guha, BJ Nelson, LA Morici, WC Wimley The Journal of membrane biology 255 (4), 503-511, 2022 | 10 | 2022 |
Optimization of host cell-compatible, antimicrobial peptides effective against biofilms and clinical isolates of drug-resistant bacteria J Ghimire, RJ Hart, A Soldano, CH Chen, S Guha, JP Hoffmann, KM Hall, ... ACS Infectious Diseases 9 (4), 952-965, 2023 | 8 | 2023 |
FOXO3 deficiency in neutrophils drives colonic inflammation and tumorigenesis J Ghimire, R Iftikhar, HM Penrose, P Snarski, E Ruiz, SD Savkovic International Journal of Molecular Sciences 24 (11), 9730, 2023 | 5 | 2023 |
Obesity-facilitated colon cancer progression is mediated by increased diacylglycerol O-acyltransferases 1 and 2 levels J Ghimire, ME Collins, P Snarski, AN King, E Ruiz, R Iftikhar, HM Penrose, ... Gastroenterology 168 (2), 286-299. e6, 2025 | 3 | 2025 |
Epiploic adipose tissue (EPAT) in obese individuals promotes colonic tumorigenesis: A novel model for EPAT-dependent colorectal cancer progression R Iftikhar, P Snarski, AN King, J Ghimire, E Ruiz, F Lau, SD Savkovic Cancers 15 (3), 977, 2023 | 3 | 2023 |
45 TUMOR PROMOTING ROLE OF EPIPLOIC ADIPOSE TISSUE IN COLON OF OBESE INDIVIDUALS IS MEDIATED VIA LIPID DROPLETS ASSOCIATED ADIPOSE TRIGLYCERIDE LIPASE (ATGL) P Snarski, M Naeem, R Iftikhar, J Ghimire, SD Savkovic Gastroenterology 166 (5), S-18, 2024 | 1 | 2024 |
Synthetic molecular evolution to identify hemocompatible antimicrobial peptides effective against drug-resistant, biofilm-forming bacteria J Ghimire, CG Starr, S Guha, JP Hoffmann, Y Wang, BJ Nelson, ... Biophysical Journal 120 (3), 143a, 2021 | 1 | 2021 |
FOXO3: at the crossroads of metabolic, inflammatory, and tumorigenic remodeling in the colon P Snarski, J Ghimire, SD Savkovic American Journal of Physiology-Gastrointestinal and Liver Physiology 326 (3 …, 2024 | | 2024 |
Peptide compositions and methods of use thereof WC Wimley, CG Starr, G Shantanu, J Ghimire US Patent App. 17/796,950, 2023 | | 2023 |
Su1257 EPIPLOIC ADIPOSE TISSUE (EPAT) IN OBESE INDIVIDUALS PROMOTES COLONIC TUMORIGENESIS: A NOVEL COLORECTAL MICROPHYSIOLOGICAL MODEL FOR STUDYING EPAT MEDIATED PROCESSIS IN … P Snarski, R Iftikhar, A King, J Ghimire, E Ruiz, F Lau, SD Savkovic Gastroenterology 164 (6), S-567, 2023 | | 2023 |
756 ELEVATED DIACYLGLYCEROL O-ACYLTRANSFERASES 1 AND 2 (DGAT1/2) REINFORCE A NEGATIVE REGULATORY LOOP OF LIPID DROPLETS AND FOXO3 TRANSCRIPTION FACTOR THAT DRIVES METABOLIC AND … J Ghimire, ME Collins, A King, R Iftikhar, HM Penrose, P Snarski, ... Gastroenterology 164 (6), S-157, 2023 | | 2023 |
Delivering the Cyclic Peptide Phalloidin to the Cell Cytosol by Membrane Translocating Carrier Peptides RP Ferrie, J Ghimire, T Fuselier, WC Wimley Biophysical Journal 120 (3), 142a, 2021 | | 2021 |
Use of Rational Engineering and Combinatorial Library Screening to Enhance Synthetically Evolved Antimicrobial Peptides J Ghimire Tulane University, 2021 | | 2021 |
Discovering Novel Hemocompatible Antimicrobial Peptides using High-throughput Screening and Rational Variation J Ghimire, CG Starr, WC Wimley, S Guha, JP Hoffmann, Y Wang, ... Biophysical Journal 118 (3), 235a, 2020 | | 2020 |