Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine LS Ross, SK Dhingra, S Mok, T Yeo, KJ Wicht, K Kümpornsin, ... Nature communications 9 (1), 3314, 2018 | 238 | 2018 |
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention RL Summers, CFA Pasaje, JP Pisco, J Striepen, MR Luth, K Kumpornsin, ... Cell chemical biology 29 (2), 191-201. e8, 2022 | 66 | 2022 |
The antimalarial natural product salinipostin A identifies essential α/β serine hydrolases involved in lipid metabolism in P. falciparum parasites E Yoo, CJ Schulze, BH Stokes, O Onguka, T Yeo, S Mok, NF Gnädig, ... Cell chemical biology 27 (2), 143-157. e5, 2020 | 60 | 2020 |
Origin of robustness in generating drug-resistant malaria parasites K Kümpornsin, C Modchang, A Heinberg, EH Ekland, P Jirawatcharadech, ... Molecular biology and evolution 31 (7), 1649-1660, 2014 | 52 | 2014 |
Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine D Loesbanluechai, N Kotanan, C de Cozar, T Kochakarn, MR Ansbro, ... International Journal for Parasitology: Drugs and Drug Resistance 9, 16-22, 2019 | 46 | 2019 |
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy SC Xie, RD Metcalfe, E Dunn, CJ Morton, SC Huang, T Puhalovich, Y Du, ... Science 376 (6597), 1074-1079, 2022 | 42 | 2022 |
A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin D Qiu, JV Pei, JEO Rosling, V Thathy, D Li, Y Xue, JD Tanner, ... Nature communications 13 (1), 5746, 2022 | 40 | 2022 |
Genomic surveillance of SARS-CoV-2 in Thailand reveals mixed imported populations, a local lineage expansion and a virus with truncated ORF7a K Joonlasak, EM Batty, T Kochakarn, B Panthan, K Kümpornsin, ... Virus Research 292, 198233, 2021 | 36 | 2021 |
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum K Kümpornsin, T Kochakarn, T Yeo, J Okombo, MR Luth, J Hoshizaki, ... Nature Communications 14 (1), 3059, 2023 | 30 | 2023 |
Fitness Loss under Amino Acid Starvation in Artemisinin-Resistant Plasmodium falciparum Isolates from Cambodia D Bunditvorapoom, T Kochakarn, N Kotanan, C Modchang, K Kümpornsin, ... Scientific reports 8 (1), 12622, 2018 | 29 | 2018 |
Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine. Nat Commun 9: 3314 LS Ross, SK Dhingra, S Mok, T Yeo, KJ Wicht, K Kümpornsin, ... | 27 | 2018 |
Biochemical and functional characterization of Plasmodium falciparum GTP cyclohydrolase I K Kümpornsin, N Kotanan, P Chobson, T Kochakarn, P Jirawatcharadech, ... Malaria journal 13, 1-11, 2014 | 24 | 2014 |
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum F Rocamora, P Gupta, ES Istvan, MR Luth, EF Carpenter, K Kümpornsin, ... ACS Infectious Diseases 7 (4), 811-825, 2021 | 17 | 2021 |
Comparative genome analysis between southeast Asian and south American Zika viruses T Kochakarn, N Kotanan, K Kümpornsin, D Loesbanluechai, ... Asian Pacific Journal of Tropical Medicine 9 (11), 1048-1054, 2016 | 17 | 2016 |
Plasmodium falciparum malaria: Convergent evolutionary trajectories towards delayed clearance following artemisinin treatment P Wilairat, K Kümpornsin, T Chookajorn Medical Hypotheses 90, 19-22, 2016 | 17 | 2016 |
Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites P Ponsuwanna, T Kochakarn, D Bunditvorapoom, K Kümpornsin, TD Otto, ... Malaria Journal 15, 1-14, 2016 | 16 | 2016 |
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target ES Istvan, F Guerra, M Abraham, KS Huang, F Rocamora, H Zhao, L Xu, ... Science translational medicine 15 (686), eadc9249, 2023 | 14 | 2023 |
Characterization of band 3–ankyrin–Protein 4.2 complex by biochemical and mass spectrometry approaches K Kümpornsin, S Jiemsup, S Yongkiettrakul, T Chookajorn Biochemical and Biophysical Research Communications 406 (3), 332-335, 2011 | 13 | 2011 |
Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine. Nat Commun. 2018; 9: 3314 LS Ross, SK Dhingra, S Mok, T Yeo, KJ Wicht, K Kumpornsin DOI: https://doi. org/10.1038/s41467-018-05652-0. PMID: https://www. ncbi …, 0 | 13 | |
A nuclear targeting system in Plasmodium falciparum K Wittayacom, C Uthaipibull, K Kumpornsin, R Tinikul, T Kochakarn, ... Malaria Journal 9, 1-5, 2010 | 12 | 2010 |