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Justin Taylor, M.D.
Justin Taylor, M.D.
Associate Professor, Sylvester Comprehensive Cancer Center, University of Miami School of Medicine
Zweryfikowany adres z miami.edu - Strona główna
Tytuł
Cytowane przez
Cytowane przez
Rok
H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers
M Seiler, A Yoshimi, R Darman, B Chan, G Keaney, M Thomas, ...
Nature medicine 24 (4), 497-504, 2018
5142018
Pirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study
AR Mato, NN Shah, W Jurczak, CY Cheah, JM Pagel, JA Woyach, ...
The Lancet 397 (10277), 892-901, 2021
4362021
Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins
SCW Lee, H Dvinge, E Kim, H Cho, JB Micol, YR Chung, BH Durham, ...
Nature medicine 22 (6), 672-678, 2016
3912016
Diagnosis and classification of hematologic malignancies on the basis of genetics
J Taylor, W Xiao, O Abdel-Wahab
Blood, The Journal of the American Society of Hematology 130 (4), 410-423, 2017
2962017
Somatic mutations and cell identity linked by Genotyping of Transcriptomes
AS Nam, KT Kim, R Chaligne, F Izzo, C Ang, J Taylor, RM Myers, ...
Nature 571 (7765), 355-360, 2019
2892019
Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations
AM Intlekofer, AH Shih, B Wang, A Nazir, AS Rustenburg, SK Albanese, ...
Nature 559 (7712), 125-129, 2018
2812018
Synthetic lethal and convergent biological effects of cancer-associated spliceosomal gene mutations
SCW Lee, K North, E Kim, E Jang, E Obeng, SX Lu, B Liu, D Inoue, ...
Cancer cell 34 (2), 225-241. e8, 2018
2312018
Spliceosomal disruption of the non-canonical BAF complex in cancer
D Inoue, GL Chew, B Liu, BC Michel, J Pangallo, AR D’Avino, T Hitchman, ...
Nature 574 (7778), 432-436, 2019
2112019
Mechanisms of Resistance to Noncovalent Bruton’s Tyrosine Kinase Inhibitors
E Wang, X Mi, MC Thompson, S Montoya, RQ Notti, J Afaghani, ...
New England Journal of Medicine 386 (8), 735-743, 2022
1802022
Diagnosis and Treatment of Myelodysplastic Syndromes: A Review
MA Sekeres, J Taylor
JAMA 328 (9), 872-880, 2022
1372022
Phase I First-in-Human Dose Escalation Study of the oral SF3B1 modulator H3B-8800 in myeloid neoplasms
DP Steensma, M Wermke, VM Klimek, PL Greenberg, P Font, ...
Leukemia 35 (12), 3542-3550, 2021
1362021
Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations
BH Durham, B Getta, S Dietrich, J Taylor, H Won, JM Bogenberger, ...
Blood, The Journal of the American Society of Hematology 130 (14), 1644-1648, 2017
1222017
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition
D Inoue, JT Polaski, J Taylor, P Castel, S Chen, S Kobayashi, SJ Hogg, ...
Nature Genetics 53 (5), 707-718, 2021
952021
Multicenter analysis of outcomes in blastic plasmacytoid dendritic cell neoplasm offers a pretargeted therapy benchmark
J Taylor, M Haddadin, VA Upadhyay, E Grussie, N Mehta-Shah, ...
Blood, The Journal of the American Society of Hematology 134 (8), 678-687, 2019
952019
Altered nuclear export signal recognition as a driver of oncogenesis
J Taylor, M Sendino, AN Gorelick, A Pastore, MT Chang, AV Penson, ...
Cancer discovery 9 (10), 1452-1467, 2019
902019
Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML
A Yoshimi, ME Balasis, A Vedder, K Feldman, Y Ma, H Zhang, SCW Lee, ...
Blood, The Journal of the American Society of Hematology 130 (4), 397-407, 2017
872017
Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis
K Togami, SS Chung, V Madan, CAG Booth, CM Kenyon, L Cabal-Hierro, ...
Cancer Discovery 12 (2), 522-541, 2022
732022
Advances in Acute Myeloid Leukemia: Recently Approved Therapies and Drugs in Development
M Stanchina, D Soong, B Zheng-Lin, JM Watts, J Taylor
Cancers 12 (11), 3225, 2020
722020
Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia
AC Leeksma, J Taylor, B Wu, JR Gardner, J He, M Nahas, M Gonen, ...
Leukemia 33 (2), 390-402, 2019
672019
Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies
J Taylor, D Pavlick, A Yoshimi, C Marcelus, SS Chung, JF Hechtman, ...
The Journal of clinical investigation 128 (9), 3819-3825, 2018
652018
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