Hippo pathway in organ size control, tissue homeostasis, and cancer FX Yu, B Zhao, KL Guan Cell 163 (4), 811-828, 2015 | 2188 | 2015 |
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling FX Yu, B Zhao, N Panupinthu, JL Jewell, I Lian, LH Wang, J Zhao, H Yuan, ... Cell 150 (4), 780-791, 2012 | 1764 | 2012 |
The Hippo pathway: regulators and regulations FX Yu, KL Guan Genes & development 27 (4), 355-371, 2013 | 1413 | 2013 |
Differential regulation of mTORC1 by leucine and glutamine JL Jewell, YC Kim, RC Russell, FX Yu, HW Park, SW Plouffe, ... Science 347 (6218), 194-198, 2015 | 771 | 2015 |
Alternative Wnt signaling activates YAP/TAZ HW Park, YC Kim, BO Yu, T Moroishi, JS Mo, SW Plouffe, Z Meng, KC Lin, ... Cell 162 (4), 780-794, 2015 | 733 | 2015 |
A gp130–Src–YAP module links inflammation to epithelial regeneration K Taniguchi, LW Wu, SI Grivennikov, PR De Jong, I Lian, FX Yu, K Wang, ... Nature 519 (7541), 57-62, 2015 | 654 | 2015 |
MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway Z Meng, T Moroishi, V Mottier-Pavie, SW Plouffe, CG Hansen, AW Hong, ... Nature communications 6 (1), 8357, 2015 | 534 | 2015 |
Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP FX Yu, J Luo, JS Mo, G Liu, YC Kim, Z Meng, L Zhao, G Peyman, ... Cancer cell 25 (6), 822-830, 2014 | 499 | 2014 |
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis T Moroishi, HW Park, B Qin, Q Chen, Z Meng, SW Plouffe, K Taniguchi, ... Genes & development 29 (12), 1271-1284, 2015 | 364 | 2015 |
Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation FX Yu, Y Zhang, HW Park, JL Jewell, Q Chen, Y Deng, D Pan, SS Taylor, ... Genes & development 27 (11), 1223-1232, 2013 | 357 | 2013 |
RAP2 mediates mechanoresponses of the Hippo pathway Z Meng, Y Qiu, KC Lin, A Kumar, JK Placone, C Fang, KC Wang, S Lu, ... Nature 560 (7720), 655-660, 2018 | 356 | 2018 |
Regulation of the Hippo–YAP pathway by protease-activated receptors (PARs) JS Mo, FX Yu, R Gong, JH Brown, KL Guan Genes & development 26 (19), 2138-2143, 2012 | 324 | 2012 |
Estrogen regulates Hippo signaling via GPER in breast cancer X Zhou, S Wang, Z Wang, X Feng, P Liu, XB Lv, F Li, FX Yu, Y Sun, ... The Journal of clinical investigation 125 (5), 2123-2135, 2015 | 237* | 2015 |
Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma TT Tang, AW Konradi, Y Feng, X Peng, M Ma, J Li, FX Yu, KL Guan, ... Molecular cancer therapeutics 20 (6), 986-998, 2021 | 166 | 2021 |
Claudin-18–mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis B Zhou, P Flodby, J Luo, DR Castillo, Y Liu, FX Yu, A McConnell, ... The Journal of clinical investigation 128 (3), 970-984, 2018 | 153 | 2018 |
The Hippo pathway in tissue homeostasis and regeneration Y Wang, A Yu, FX Yu Protein & cell 8 (5), 349-359, 2017 | 149 | 2017 |
Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis L Fu, Y Hu, M Song, Z Liu, W Zhang, FX Yu, J Wu, S Wang, ... PLoS biology 17 (4), e3000201, 2019 | 142 | 2019 |
Hippo pathway regulation of gastrointestinal tissues FX Yu, Z Meng, SW Plouffe, KL Guan Annual review of physiology 77 (1), 201-227, 2015 | 142 | 2015 |
Oncogenic activation of the PI3K/Akt pathway promotes cellular glucose uptake by downregulating the expression of thioredoxin-interacting protein SY Hong, FX Yu, Y Luo, T Hagen Cellular signalling 28 (5), 377-383, 2016 | 113 | 2016 |
GPCR-hippo signaling in cancer J Luo, FX Yu Cells 8 (1), 31, 2019 | 100 | 2019 |